Organometallic Compounds
Medchemexpress LLC Ms-PEG5-t-butyl ester | 870487-48-2 | C16H32O9S | 25 MG
Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are molecules that contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for a target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTAC linker
- PEG-based structure
- Target PROTACs
- Pathway PROTAC
- Used in the synthesis of PROTACs
Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 250 MG
Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | >95.0% | C19H32N2O5 | 10MG
BCN-exo-PEG3-NH2 is a BCN-functionalized PEG3 amine linker used in bioorthogonal conjugation and PROTAC linker synthesis. It provides a strained alkyne handle and a terminal primary amine to enable modular coupling strategies, and is commonly supplied in research-scale quantities at high reported purity.
- Provides a strained alkyne (BCN) for rapid bioorthogonal click reactions.
- Contains a PEG3 spacer for flexibility and improved solubility.
- Features a terminal primary amine for amide or reductive amination conjugation.
- Suitable for linker construction in targeted degradation and bioconjugation workflows.
- Supplied in research-scale quantities with supplier-reported high purity.
Medchemexpress LLC DBCO-S-S-PEG3-biotin | 1430408-09-5 | 96.9% | 869.12 | 25 MG
DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains a DBCO group for SPAAC reactions
- Used in the synthesis of PROTACs
Medchemexpress LLC 4,7,10,16,19,22-Hexaoxa-13-azapentacosanedioic acid, 1,25-bis(1,1-dimethylethyl) ester | 1814901-03-5 | 98.0% | C26H51NO10 | 250 MG
NH-bis(PEG3-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which are molecules designed to selectively degrade target proteins by utilizing the intracellular ubiquitin-proteasome system.
- Used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets the protein of interest.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC DNP-PEG3-azide | 951671-87-7 | 99.2% | C14H20N6O7 | 25 MG
DNP-PEG3-azide is a PEG-based PROTAC linker crucial for the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an azide group that enables both copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. It is a light yellow to yellow viscous liquid with a high purity of 99.18%.
Medchemexpress LLC Azido-PEG3-C3-OH | 1807512-36-2 | 98.0% | C9H19N3O4 | 250 MG
Azido-PEG3-C3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This click chemistry reagent features an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Azido-PEG5-triethoxysilane | 3025193-22-7 | 95.0% | C22H46N4O9Si | 50 MG
Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group, enabling it to participate in various cycloaddition reactions. PROTACs are designed to degrade target proteins via the intracellular ubiquitin-proteasome system.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Medchemexpress LLC Bromoacetamido-PEG3-azide | 940005-81-2 | ≥97.0% | C10H19BrN4O4 | 25 MG
Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- Facilitates selective degradation of target proteins through the intracellular ubiquitin-proteasome system
- Intended for research use only
Medchemexpress LLC N-(Boc-PEG3)-N-bis(PEG2-alcohol) | 2055042-60-7 | > 96.0% | C25H52N2O11 | 100 MG
N-(Boc-PEG3)-N-bis(PEG2-alcohol) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein.
- Composed of two distinct ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase and the other targets a specific protein.
- Leverages the intracellular ubiquitin-proteasome system.
- Achieves selective degradation of target proteins.
Medchemexpress LLC M-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 10 G
m-PEG5-Br is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting the protein of interest. These compounds function by exploiting the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
Medchemexpress LLC N-(Azido-PEG3)-N-Boc-PEG4-Boc | 2112731-94-7 | C28H54N4O11 | 100 MG
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker. It is a click chemistry reagent that contains an Azide group.
- Can be used in the synthesis of PROTACs.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Medchemexpress LLC m-PEG5-NH2 | 5498-83-9 | MFCD00010996 | 99.0% | C11H25NO5 | 1 G
m-PEG5-NH2 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs function by connecting two ligands-one for an E3 ubiquitin ligase and another for a target protein-to leverage the intracellular ubiquitin-proteasome system for selective protein degradation. The product has a purity of 99.02%.
- Peg-based protac linker
- Used in the synthesis of protacs
- Facilitates protein degradation via the ubiquitin-proteasome system
- High purity
Medchemexpress LLC NH-bis(PEG3-Boc) | 1814901-03-5 | 98.0% | C26H51NO10 | 50 MG
NH-bis(PEG3-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules connect two different ligands: one for an E3 ubiquitin ligase and another for a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- PEG-based linker
- Essential for PROTAC synthesis
- Enables targeted protein degradation
Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 5 G
Aminooxy-PEG3-C2-NH-Boc is a PROTAC linker, specifically a PEG- and Alkyl/ether-based linker, utilized in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They function by connecting two different ligands: one that binds to an E3 ubiquitin ligase and another that targets a specific protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Connects a ligand for an E3 ubiquitin ligase to a target protein
- Facilitates selective degradation of target proteins