Organometallic Compounds
Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG
N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Applications in cancer-programmed cell death
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 10 G
Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Utilized in the synthesis of PROTACs.
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
Medchemexpress LLC Azido-PEG5-azide | 356046-26-9 | 99.98% | 332.36 | 500 MG
Azido-PEG5-azide is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- For research use only
Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | 99.9% | 368.47 | 250 MG
BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity: 99.94%
- Molecular weight: 368.47
- Chemical formula: C19H32N2O5
- CAS number: 1841134-72-2
- Appearance: Colorless to light yellow liquid
- Density: 1.14±0.1 g/cm3
- Used in PROTAC synthesis
- Contains a BCN group for SPAAC reactions
Medchemexpress LLC N3-PEG3-CH2CH2-Boc | 252881-73-5 | ≥98.0% | 303.35 g·mol⁻¹ | C13H25N3O5 | 250 MG
N3-PEG3-CH2CH2-Boc is a Boc-protected, azide-terminated PEG3 linker used in conjugation chemistry for synthesizing PROTACs and antibody-drug conjugates. It contains a three-unit polyethylene glycol spacer with an azide functional group that enables click chemistry reactions such as copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC).
- Boc-protected azide terminus for selective conjugation.
- Three-unit PEG spacer provides flexibility and improves solubility.
- Compatible with CuAAC and SPAAC click reaction methodologies.
- High purity suitable for synthetic applications (≥98.0%).
- Available in multiple pack sizes, including 250 MG.
Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 1 MG
(S,R,S)-AHPC-C2-PEG3-BCN is a VHL ligand used for the synthesis of PROTACs. This product is intended for research use only.
- VHL ligand
- Used for the synthesis of PROTACs
- For research use only
Medchemexpress LLC N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid | 2183440-74-4 | 98.1% | C29H55N5O13 | 10MG
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based linker designed for use in click chemistry and bioconjugation workflows. It features a terminal azide and orthogonally protected amine, providing versatility for PROTAC assembly and other synthetic applications.
- Terminal azide for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC).
- PEG3 spacer provides flexibility and improved solubility.
- Boc-protected amine on PEG2 enables selective deprotection and further modification.
- Carboxylic acid terminus allows conjugation via standard amide coupling.
- High purity suitable for synthetic and bioconjugation workflows.