OSI-930 is a small-molecule tyrosine kinase inhibitor selective for c-Kit, KDR (VEGFR2), and CSF-1R (c-Fms). It is used in preclinical research to probe kinase signaling, inhibit angiogenesis, and study antitumor effects; the compound is supplied in solid and solution formats for laboratory use.
- Selective inhibitor of c-Kit, KDR (VEGFR2), and CSF-1R.
- Potent biochemical activity with low-nanomolar IC50 values (example: KDR ≈9 nM).
- Supplied in solid and solution forms, available in small research pack sizes.
- Molecular weight 443.44 g/mol; formula C22H16F3N3O2S.
- High purity (≈98% by RP-HPLC), suitable for preclinical assays.