Glycosyl compounds
Medchemexpress LLC D(+)-Trehalose dihydrate | 6138-23-4 | 378.3 g/mol | 5 G
D-(+)-Trehalose dihydrate is an orally active disaccharide that exhibits anti-desiccant and cryopreservative activities. It functions as an osmolyte and stress protectant, aiding in carbon storage and transport. This product can be utilized as a food ingredient and pharmaceutical excipient.
- Orally active disaccharide
- Anti-desiccant activity
- Cryopreservative activity
- Acts as an osmolyte
- Stress protectant
- Aids in carbon storage and transport
- Suitable for use as a food ingredient
- Suitable for use as a pharmaceutical excipient
Medchemexpress LLC SP-D Rhesus Macaque 10ug | 10ug
The SP-D protein plays a critical role in the lung s defense mechanisms against inhaled microorganisms organic antigens and toxins This multifunctional protein interacts with a variety of compounds including bacterial lipopolysaccharides oligosaccharides and fatty acids to modulate leukocyte activity in immune responses SP-D Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived SP-D protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Lactose (Standard) | 63-42-3 | 99.9% | 100 MG
Lactose (Standard) is an analytical standard of Lactose, intended for research and analytical applications. It is a β-galactoside consisting of galactose and glucose residues, commonly found as the main carbohydrate in mammalian breast milk. As a macronutrient and inducer of host innate immune responses, it possesses immune modulatory functions.
- Used as an analytical standard.
- Supports qualitative, quantitative, and methodological research experiments.
- Suitable for use in HPLC, GC, and MS applications.
Medchemexpress LLC KVA-D-88 | 2410550-31-9 | 99.8% | 382.19 | C17H11Cl2F2N3O | 5 MG
KVA-D-88 is a small-molecule, selective phosphodiesterase 4B (PDE4B) inhibitor supplied for research use in pharmacology and neuroscience studies. It has been used in vivo to investigate modulation of reward-related behaviors and cAMP signaling pathways.
- Selective inhibition of PDE4B, useful for target-specific studies.
- High chemical purity suitable for research assays.
- Powder form facilitates formulation and dosing flexibility.
- Stable under recommended low-temperature storage conditions.
- Reported molecular weight and formula available for analytical confirmation.
Medchemexpress LLC D-(+)-Trehalose dihydrate | 6138-23-4 | 378.33 | 1 ML
D-(+)-Trehalose dihydrate, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipient. It is a safe, naturally occurring disaccharide.
- Isolated from Saccharomyces cerevisiae
- Can be used as a food ingredient
- Can be used as a pharmaceutical excipient
- Naturally occurring disaccharide
Medchemexpress LLC Sucrose octasulfate sodium | 74135-10-7 | 98.0% | 1158.66 | 500 MG
Sucrose octasulfate sodium, a sulfated oligosaccharide derivative, acts as a matrix metalloproteinase (MMP) inhibitor. It stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach, directly affecting D cells in the gastric mucosa, which contributes to its ulcer-healing effect. This compound can be used as a pharmaceutical excipient, significantly improving wound closure in diabetic foot ulcers (nerve ischemia) and venous leg ulcers, and is also used in chronic wound healing studies.
- MMP inhibitor
- Stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach
- Exerts ulcer-healing effects by releasing endogenous gastric somatostatin
- Can be used as a pharmaceutical excipient
- Significantly improves wound closure in diabetic foot ulcers and venous leg ulcers
- Useful for chronic wound healing studies
Medchemexpress LLC Prosaikogenin D | 103629-72-7 | 5 MG
Prosaikogenin D is a triterpene compound isolated from the roots of *Buleurum bicaule Helm*. This solid, white to off-white compound exhibits anti-cancer activity, notably suppressing the proliferation of A549 cells with an IC50 of 57.2 μg/mL in in vitro studies.
- High purity of 99.62%.
- In vitro soluble in DMSO at 100 mg/mL.
- In vivo clear solutions at ≥ 5 mg/mL with specific solvent protocols.
- Isolated from the roots of *Buleurum bicaule Helm*.
- Exhibits anti-cancer activity.
- For research use only.
Medchemexpress LLC CHMFL-PI4K-127 | 2377604-81-2 | C18H15ClN4O3S | 100 MG
CHMFL-PI4K-127 (compound 15g) is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor with an IC50 of 0.9 nM. It demonstrates potent activity against 3D7 Plasmodium falciparum, exhibiting an EC50 of 25.1 nM. This compound shows antimalaria efficacy, displaying high selectivity against PfPI4K over human lipid and protein kinases. In vivo studies in rodent models demonstrated significant antimalarial activities in a dose-dependent manner, generating curative effects in the blood stage at 80 mg/kg and full protection in the liver stage at 1 mg/kg.
- Potent and highly selective PfPI4K inhibitor
- Orally active
- Shows antimalaria efficacy
- High selectivity against PfPI4K over human lipid and protein kinases
- Significant antimalarial activities in rodent models
Medchemexpress LLC Garcinone D | 107390-08-9 | 10 MM 1 ML
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC50 for CDK2/CyclinE1 is 28.23 μM). It promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression, and enhancing the Nrf2/HO-1 signaling pathway. Additionally, it blocks the tumor cell cycle by inhibiting CDK2/CyclinE1 and can inhibit prostate and breast cancer.
- Activator of STAT3/Cyclin D1 and Nrf2/HO-1 pathways
- Inhibitor of CDK2/CyclinE1
- Promotes neural stem cell proliferation
- Blocks tumor cell cycle
- Regulates C17.2 neural stem cell viability
- Promotes G1-S phase transition and arrests cell cycle in S phase in C17.2 neural stem cells
- Increases p-STAT3, Cyclin D1, Nrf2, and HO-1 proteins in C17.2 neural stem cells
Apexbio Technology LLC Inosine 58-63-9 10mM (in 1mL DMSO)
Inosine (58-63-9) is an endogenous purine nucleoside It participates in purine catabolic and salvage pathways facilitating nucleotide synthesis and uric acid formation Inosine is structurally composed of hypoxanthine linked to a ribose sugar moiety It is also present in specific tRNA anticodons influencing translational processes Inosine exerts its biological activity by serving as an intermediate in purine metabolism and modulating nucleotide recycling and tRNA modifications In biochemical and cell biology studies inosine is utilized as a tool compound to investigate purine metabolism nucleotide recycling pathways tRNA modifications receptor-mediated signaling and immune regulation in vitro Reported IC50 values may vary depending on biological models and experimental conditions applied Based on these pharmacological properties inosine holds research potential in studies of purine metabolism nucleotide synthesis RNA biology and immune regulation
Medchemexpress LLC 2-O-α-D-Glucopyranosyl-L-ascorbic Acid | 129499-78-1 | 50 MG
2-O-α-D-Glucopyranosyl-L-ascorbic Acid | 129499-78-1 | 50 MG
Cambridge Isotope Laboratories Benzo[c]phenanthrene (13C6 99%) 100 ug/mL in nonane 1 2 mL
Benzo[c]phenanthrene (13C6 99%) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC a-D-Galactose pentaa 50g
-D-Galactose pentaacetate (Pentaacetyl- -D-galactopyranose) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC D-(+)-Phenyllactic acid | 7326-19-4 | 99.9% | 166.18 | 1 ML
D-(+)-Phenyllactic acid is an antibacterial agent excreted by Geotrichum candidum. It inhibits a range of Gram-positive and Gram-negative bacteria found in humans and foodstuffs. This product is for research use only and not sold to patients.
- Inhibits Mcl-1 and Bim interaction with an IC50 of 0.161 μM.
- Inhibits cell viability of SKBR-3 with an EC50 of 112.69 nM.
- Exhibits broad-spectrum antibacterial effect against L. monocytogenes, S. aureus, E. faecalis, and K. oxytoca.
- White to off-white solid.
- Soluble in DMSO and H₂O.