Glycosyl compounds
Medchemexpress LLC Sapintoxin D | 80998-07-8 | 99.9% | 1 MG
Sapintoxin D is a fluorescent phorbol ester used for studying the activation of protein kinase C (PKC). It acts as a calcium-dependent PKC activator and exhibits antiviral activity against HIV2 ROD, HIV1 3B in MT4 cells, and chikungunya virus in Vero cells. Its molecular weight is 539.62, and its formula is C30H37NO8. It appears as a white to off-white solid and is derived from Plants Euphorbiaceae Shirakiopsis indica (Willd.) Esser. It is intended for research use only.
- Fluorescent phorbol ester
- Utilized for studying the activation of protein kinase C (PKC)
- Calcium-dependent PKC activator
- Demonstrated antiviral activity against HIV2 ROD and HIV1 3B in MT4 cells
- Demonstrated antiviral activity against chikungunya virus in Vero cells
- White to off-white solid appearance
- Derived from Plants Euphorbiaceae Shirakiopsis indica
- For research use only
Medchemexpress LLC Alpha Sarcoglycan Antibody (YA2068) | 10 UL
The alpha Sarcoglycan Antibody (YA2068) is a Rabbit-derived, non-conjugated IgG monoclonal antibody designed to target alpha Sarcoglycan. Alpha Sarcoglycan is a component of the sarcoglycan complex, which forms a structural link between the F-actin cytoskeleton and the extracellular matrix.
- Applications include WB, IHC-P, and IP
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Store at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Liquid appearance
- Rabbit host
- Reactivity with human, mouse, and rat samples
- Non-conjugated
- Affinity purified
Medchemexpress LLC Fluorescein Di-β-D-Glucuronide | 134869-04-8 | HY-D1460 | 96.6% | 684.55 | 5 MG
Fluorescein Di-β-D-Glucuronide is a fluorescent probe used for non-invasive imaging of intestinal bacterial β-glucuronidase activity in nude mice. It reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, facilitating pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies.
- Fluorescent probe
- Utilized for non-invasive imaging of intestinal bacterial β-glucuronidase activity
- Reveals in vitro and in vivo activity of intestinal bacterial β-glucuronidase
- Facilitates pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors
- Classified as Fluorescent Dye, Enzyme Labeling, Protease Substrate
- Relevant to Disease Areas: Infection, β-glucuronidase, Bacterial
Medchemexpress LLC Galactose 1-phosphate Potassium salt | 19046-60-7 | 99.0% | 336.32 | 25 MG
Galactose 1-phosphate Potassium salt is an intermediate involved in galactose metabolism and nucleotide sugars. It acts as an inhibitor for several enzymatic activities, including phosphoglucomutase, glucose-6-phosphate phosphatase, glucose-6-phosphate dehydrogenase, glycogen phosphorylase, UDP-glucose pyrophosphorylase, and inositol monophosphatase. It is intended for research use only.
- Intermediate in galactose metabolism and nucleotide sugars.
- Inhibitor of various enzymatic activities (phosphoglucomutase, glucose-6-phosphate phosphatase, glucose-6-phosphate dehydrogenase, glycogen phosphorylase, UDP-glucose pyrophosphorylase, and inositol monophosphatase).
- Available in solid and solution forms.
- High purity (99.0%).
Medchemexpress LLC Prostaglandin D Synthase Antibody (YA1739) | 100 UL
Prostaglandin D Synthase Antibody (YA1739) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Prostaglandin D Synthase. This protein acts as a glutathione-independent prostaglandin D synthase, converting prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2). PGD2 plays various roles as a neuromodulator, a trophic factor in the central nervous system, and is involved in smooth muscle contraction/relaxation, as well as being a potent inhibitor of platelet aggregation. The related gene is primarily expressed in the brain, with studies suggesting its involvement in regulating non-rapid eye movement sleep.
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Liquid appearance
- Reactivity with human, mouse, and rat
- Applications: WB, IHC-P, IHC-F, ICC/IF
Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 98.0% | 148.11 | 1 ML
D-α-Hydroxyglutaric acid is the primary metabolite that accumulates in the neurometabolic disorder D-2-hydroxyglutaric aciduria. It acts as a weak competitive antagonist of α-ketoglutarate (α-KG), inhibiting multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. This compound increases reactive oxygen species (ROS) production, binds to and inhibits ATP synthase, and suppresses mTOR signaling. It also accumulates in human cancers with neomorphic mutations in IDH1 and IDH2 genes.
- Weak competitive antagonist of α-ketoglutarate (α-KG).
- Inhibits multiple α-KG-dependent dioxygenases.
- Increases reactive oxygen species (ROS) production.
- Binds to and inhibits ATP synthase.
- Suppresses mTOR signaling.
- Accumulates in human cancers with IDH1 and IDH2 gene mutations.
![Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 500 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659706.jpg-250.jpg)
Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 500 G
Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 500g, is a high-quality reagent used extensively in molecular biology and biochemistry laboratories. This ultra-pure formulation ensures minimal contaminants, making it ideal for experiments that require precise pH control and minimal interference from impurities. Tris Base is commonly used to prepare Tris-buffered solutions for protein purification, enzyme assays, and nucleic acid research. The 500g size is perfect for mid-sized laboratories or for researchers requiring consistent buffer preparation for electrophoresis, PCR, and other biochemical assays. Its ability to maintain pH stability in a wide range of conditions makes it a versatile reagent in the lab.
![Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 5 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659707.jpg-250.jpg)
Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 5 Kg
Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 5kg, is a high-purity reagent used in a variety of biochemical and molecular applications, particularly for preparing buffer solutions. Tris Base is essential for maintaining a stable pH in biological and chemical experiments, which makes it indispensable in protein analysis, electrophoresis, and enzyme activity studies. The 5kg size is ideal for larger laboratories or those involved in frequent buffer preparation. Its ultra-pure quality ensures minimal interference with sensitive experiments, making it suitable for protein purification, DNA analysis, and other molecular biology techniques where precise pH control is necessary.
![Alkali Scientific 1 O Methyl α D mannopyranoside [Methyl α D Mannopyranoside], 100 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659627.jpg-250.jpg)
Alkali Scientific 1 O Methyl α D mannopyranoside [Methyl α D Mannopyranoside], 100 G
Methyl α-D-Mannopyranoside (100g) is a high-quality carbohydrate reagent used in laboratory experiments that require a stable and reliable source of this sugar derivative. Methyl α-D-Mannopyranoside is used in biochemical research for the study of glycosidic bonds, carbohydrate-protein interactions, and in the synthesis of oligosaccharides and glycoproteins. This reagent is commonly employed in research on carbohydrate chemistry, enzymology, and cell biology. The 100g bottle is ideal for medium to large-scale experiments, offering an essential carbohydrate derivative for researchers studying molecular interactions, glycosylation, and other sugar-related biochemical processes.
![Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 1 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659787.jpg-250.jpg)
Alkali Scientific Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane], 1 Kg
Tris Base Ultra Pure, 1 kilogram, is a highly purified form of TRIS (tris(hydroxymethyl)aminomethane), commonly used in laboratory applications that require a stable buffering agent. This large 1kg container is ideal for high-throughput laboratories or research facilities that prepare significant volumes of buffer solutions for ongoing experiments. Tris is essential in maintaining a stable pH in molecular biology and biochemistry, especially in nucleic acid extraction, enzyme reactions, and electrophoresis. The ultra-pure grade ensures that the product is free from impurities, making it suitable for sensitive techniques where contamination could compromise experimental results.
Alkali Scientific p Nitrophenyl α D mannopyranoside, 1 G
p-Nitrophenyl α-D Mannopyranoside, 1g, is used in biochemical assays to measure α-mannosidase activity. The substrate is cleaved by α-mannosidase, producing a yellow color that indicates enzyme activity, allowing researchers to monitor and quantify the enzyme's action. This reagent is valuable in the study of carbohydrate metabolism and enzyme kinetics, and it is commonly used in genetic research and microbiology to investigate enzyme functions. The 1g quantity is ideal for smaller laboratory assays and experimental setups, providing enough material for repeated trials. It offers a simple, reliable method for studying enzyme-substrate interactions and the functionality of α-mannosidase in various biological contexts.
Medchemexpress LLC Leniolisib (phosphate) | 1354691-97-6 | 99.10% | 548.45 | 25 MG
Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. It has potential for treating immunodeficiency disorders.
- Potent and selective PI3Kδ inhibitor.
- Potential for immunodeficiency disorders treatment.
- Suppresses increased pathway activity (measured as phosphorylation of AKT or S6) caused by APDS mutant p110δ in a concentration-dependent manner.
Alkali Scientific p Nitrophenyl α D mannopyranoside, 500 Mg
p-Nitrophenyl α-D Mannopyranoside, 500mg, is a biochemical reagent used for studying α-mannosidase activity. This compound serves as a substrate for α-mannosidase, where the enzyme cleaves the bond between the p-nitrophenyl group and the α-D-mannopyranoside molecule, releasing a yellow product. This colorimetric reaction is commonly used in enzyme assays to study enzyme kinetics, carbohydrate metabolism, and for genetic research. The 500mg size is suitable for multiple experiments or larger-scale studies. It is commonly used in laboratory assays to monitor enzyme activity, particularly in microbiological studies and enzyme research, providing a reliable and simple method for enzyme analysis.
Alkali Scientific 2 Nitrophenyl β D Xylopyranoside, 500 Milligrams
2-Nitrophenyl β-D-xylopyranoside (500 mg) is a substrate used for studying xylanase activity in enzymatic assays. Xylanases, which break down xylan (a hemicellulose), can cleave this substrate, producing p-nitrophenol that is easily measured by its absorbance at 405 nm. This reagent is crucial for biochemists studying the hydrolysis of hemicellulose, a major component of plant cell walls. It has applications in areas such as agricultural research, biofuel production, and the characterization of enzymes that degrade plant biomass. The 500 mg quantity makes it suitable for both small- and large-scale enzyme activity testing.
Alkali Scientific D (+) Trehalose Dihydrate, 50 G
D (+) Trehalose Dihydrate, 50g, is a carbohydrate stabilizing agent used to protect cells, proteins, and enzymes during environmental stress such as dehydration, freezing, and oxidative conditions. Trehalose stabilizes cellular structures, preserves protein functions, and protects sensitive biological molecules from degradation. This 50g bottle is ideal for smaller-scale research projects and biochemical applications where cell protection and sample preservation are critical. It is commonly used in fields such as cryobiology, drug formulation, and the preservation of enzymes and microbial cultures during long-term storage, providing a reliable solution for stabilizing biological samples.