Glycosyl compounds
Medchemexpress LLC IL-12 beta Rat HEK 50ug
IL-12 beta Protein also known as natural killer cell stimulatory factor 2 is a common subunit (p40) of IL-12 and IL-23 IL-12 is a inflammatory factor expressed by activated macrophages and involves in Th1-type immune response against cancer[1] IL-12 beta Protein located outside the cell membrane involves in singalling mediated by Jak-STAT[3] IL-12 beta Protein consists of 335 amino acids (M1-S335) with a lg-like domain (43-90 a a) IL-12 beta Protein Rat (M1-S335) is produced in HEK293 cells with a C-Terminal His-tag
Medchemexpress LLC BETA-1 | 2924598-24-1 | C37H28IN3S2 | 5 MG
BETA-1 is the first twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule. It emits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria. BETA-1 can be utilized for simultaneous and dual-color imaging of LDs and mitochondria both in vivo and in vitro.
- Emits cyan fluorescence in lipid droplets (LDs).
- Emits red fluorescence in mitochondria.
- Can be used for simultaneous and dual-color imaging of LDs and mitochondria in vivo and in vitro.
Medchemexpress LLC Interleukin-10 receptor subunit beta, mouse recombinant (HEK293, His-tag) | >98.0% | 500 UG
Recombinant mouse interleukin-10 receptor subunit beta expressed in HEK293 cells and supplied as a C-terminal His-tagged, purified protein for research use. Characterization data such as purity, molecular weight, and formulation are available from the supplier.
Medchemexpress LLC Beta III Tubulin Antibody (YA4243) | 50 kDa | 10 UL
Beta III Tubulin Antibody (YA4243) is a monoclonal antibody targeting beta III Tubulin. It is also known as tubulin, beta 3; MC1R; and TUBB4. This antibody is reactive with human, mouse, and rat samples.
- Suitable for various applications including Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (FC), and Enzyme-Linked Immunosorbent Assay (ELISA).
- Monoclonal antibody with high specificity.
- Predicted and observed molecular weight is 50 kDa.
Medchemexpress LLC Octyl α-D-glucopyranoside | 29781-80-4 | 98.0% | 292.37 | 1 ML
Octyl α-D-glucopyranoside is a biochemical reagent suitable for life science-related research, functioning as a biological material or organic compound. It is provided in a solid form, appearing as white to off-white, and has a molecular weight of 292.37. It is intended for research use only.
- Biochemical reagent for life science research.
- Can be used as a biological material or organic compound.
- Available as a white to off-white solid.
- For research use only.
Medchemexpress LLC NRG1-beta 1 Human 500ug
NRG1-beta 1 Protein a specific ligand for ERBB3 belongs to a family of structurally related polypeptide growth factors NRG1-beta 1 Protein can regulate cell proliferation differentiation apoptosis and migration NRG1-beta 1 Protein plays an important role in tumors and neurological diseases and also has certain neuroprotective activity NRG-1 Protein Human is a recombinant NRG1-beta 1 protein expressed by E coli without tags[1][2][3][4][5]
Medchemexpress LLC Ethyl β-D-glucopyranoside | 3198-49-0 | 5 MG
Ethyl β-D-glucopyranoside (compound 10) is an ethyl derivative that can be isolated from the ethanolic extract of Scabiosa stellata LS. It is intended for research use only.
- Store at 4°C, protected from light.
- If in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
Medchemexpress LLC Beta-Cortol | 667-65-2 | 99.9% | 368.51 | 1 ML
Beta-Cortol is an O-glycosylated compound and cortisol metabolite, isolated from the leaves of mulberry cultivar Yu 711. Its concentration significantly decreases when the plant is subjected to drought stress. It functions as a biomarker, as serum Beta-Cortol levels in early non-small cell lung cancer models are downregulated to 1/8 of the preoperative level after tumor resection. Due to these notable changes under specific pathological conditions, Beta-Cortol is broadly utilized in studies concerning early non-small cell lung cancer.
- O-glycosylated compound and cortisol metabolite.
- Isolated from the leaves of mulberry cultivar Yu 711.
- Concentration decreases significantly in plants under drought stress.
- Biomarker for early non-small cell lung cancer, with serum levels dropping to 1/8 of preoperative levels after tumor resection.
- Widely used in studies related to early non-small cell lung cancer.
Medchemexpress LLC TGF beta Receptor II Antibody | 50 UL
The TGF beta Receptor II Antibody is a Rabbit-derived, non-conjugated IgG polyclonal antibody designed to target TGF beta Receptor II. This transmembrane protein is crucial for binding TGF-beta, forming a complex that phosphorylates proteins to regulate gene transcription. It plays a significant role in cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumor genesis. Mutations in the associated gene have been linked to various health conditions including Marfan Syndrome and Loeys-Deitz Aortic Aneurysm Syndrome.
- Rabbit-derived polyclonal antibody
- Non-conjugated IgG isotype
- Targets TGF beta Receptor II
- Reactive with human, mouse, and rat samples
- Applications include WB, ELISA, IHC-P, and ICC/IF
- Formulated in PBS with 50% glycerol, 0.5% BSA, and 0.02% sodium azide
- Stable for 1 year at -20°C; avoid freeze/thaw cycles
- Affinity purified
Medchemexpress LLC Phospho-PDGFR beta (Tyr740) Antibody (YA3062) | 10 UL
Phospho-PDGFR beta (Tyr740) Antibody (YA3062) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Phospho-PDGFR beta (Tyr740). PDGF Receptor beta is a tyrosine-protein kinase functioning as a cell-surface receptor for homodimeric PDGFB and PDGFD, and heterodimers formed by PDGFA and PDGFB. It plays essential roles in embryonic development, cell proliferation, survival, differentiation, chemotaxis, and migration, with critical involvement in blood vessel development and cardiovascular system formation.
- Rabbit-derived host
- Reactivity: Mouse, Rat
- Non-conjugated IgG monoclonal antibody
- Applications: WB, ICC/IF
- Purity by affinity chromatography
- Supplied in 10 mM PBS, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol
- Stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Liquid appearance, shipped with blue ice
- Concentration: 0.6 mg/mL
Medchemexpress LLC DNA polymerase beta Protein, Human (His) | 100 UG
DNA polymerase beta Protein, Human (His) is a DNA repair enzyme crucial for maintaining genomic integrity. It plays a vital role in base excision repair (BER), a fundamental pathway essential for DNA maintenance, replication, recombination, and drug resistance. This protein belongs to the DNA polymerase type-X family and is involved in multiple DNA repair mechanisms.
- Involved in various types of DNA repair mechanisms
- Performs base excision repair (BER)
- Essential for DNA maintenance, replication, recombination, and drug resistance
- Belongs to the DNA polymerase type-X family
- Composed of an 8-kDa domain and a 31-kDa domain
- Also involved in Nucleotide Excision Repair (NER), Mismatch Repair (MMR), and Double Strand Break Repair (DSBR)
- Species: Human
- Source: E. coli
- Purity: ≥ 95%
Medchemexpress LLC Phenyl β-D-glucopyranoside | 1464-44-4 | 99.85% | 256.25 | 1 ML
Phenyl β-D-glucopyranoside is a compound isolated from Phellodendron amurense. It demonstrates anti-inflammatory and anti-tumor activities by inhibiting nitric oxide (NO) production and the expression of iNOS and COX-2. Additionally, it impedes the nuclear translocation of NF-κB and the expression of pro-inflammatory cytokines and related genes.
- Significantly inhibits the expression of inflammatory factors (IL-1β, TNF-α, IL-6, COX-2, CXCL1, MCP-1) induced by LPS in Raw 264.7 cells.
- Concentration-dependently inhibits MMP-2 and MMP-9 enzyme activity and Ninj1 expression in Raw 264.7 cells.
- Inhibits adhesion to fibronectin, type I collagen, laminin, and gelatin in Raw 264.7 cells.
Medchemexpress LLC IL-1 beta Rhesus ma 100ug
Recombinant interleukin-1 beta (IL-1β) from rhesus macaque supplied as a purified protein for in vitro immunology and cell signaling research. The product contains the mature cytokine sequence (153 amino acids, A117-S269), is reported at ≥98% purity, and has an approximate molecular weight of 18.4 kDa by SDS-PAGE. Intended for research use to study inflammatory signaling and cytokine responses.
- Contains mature cytokine sequence (153 amino acids, A117-S269).
- High purity (≥98%) reduces background in downstream assays.
- Approximate molecular weight ~18.4 kDa confirmed by SDS-PAGE.
- Suitable for in vitro immunology and cell signaling studies.
- Available in small-scale quantities for assay development (100 μg).
Selleck Chemical LLC Cytochalasin D
Cytochalasin D (Zygosporin A NSC 209835) is a potent actin polymerization inhibitor derived from fungus Cytochalasin D inhibits actin filament dynamics in cells It induces phosphorylation and cytoplasmic retention of Yap