Cucurbitacin D is the active ingredient in Trichosanthes kirilowii and can disrupt the interaction between Hsp90 and two co-chaperones, Cdc37 and p23. It is also an inflammasome activator, inducing cell cycle arrest and cell apoptosis, exhibiting anti-tumor and anti-inflammatory effects.
- Active ingredient in Trichosanthes kirilowii.
- Disrupts the interaction between Hsp90 and co-chaperones Cdc37 and p23.
- Acts as an inflammasome activator.
- Induces cell cycle arrest and cell apoptosis.
- Exhibits anti-tumor and anti-inflammatory effects.
- Purity: 99.93%.
- Appearance: Solid, white to off-white.
- Structure classification: Terpenoids, triterpenes.
- Initial source: Plants, Cucurbitaceae, Trichosanthes kirilowii Maxim.
- For research use only.