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Filtered Search Results
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 250 G
EDTA Disodium Salt (250 g) is a versatile chelating agent used in various laboratory applications to bind metal ions and prevent metal-catalyzed reactions. This reagent is commonly used in molecular biology, biochemistry, and analytical chemistry for tasks like DNA extraction, protein purification, and enzyme inhibition studies. EDTA functions by sequestering divalent and trivalent metal ions, preventing them from interfering with chemical reactions or biological processes. Its ability to stabilize samples by controlling metal ion concentration makes it an essential component in laboratory research, clinical diagnostics, and various analytical techniques that require metal ion control.
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Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 25 MG
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K-Ras ligand-Linker Conjugate 4 incorporates a ligand for the K-Ras recruiting moiety and a PROTAC linker. This linker recruits E3 ligases such as VHL, CRBN, MDM2, and IAP. It can be used in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells. PROTACs consist of two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Incorporates a ligand for the K-Ras recruiting moiety
- Includes a PROTAC linker that recruits E3 ligases (VHL, CRBN, MDM2, and IAP)
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- Can be used in the synthesis of PROTAC K-Ras Degrader-1
- For research use only
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Medchemexpress LLC D-xylulose 5-phosphate sodium | 105931-44-0 | MFCD00070073 | 90.0% | 252.09 g/mol | C5H10NaO8P | 10mg
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D-Xylulose 5-phosphate (sodium) is a pentose phosphate ester and an essential intermediate metabolite in the pentose phosphate pathway (PPP) and the non-oxidative phase of the pentose phosphate pathway D-xylulose-5-phosphate can be efficiently synthesized through the phosphorylation of D-xylulose catalyzed by D-xylulokinase (XKS1 from Saccharomyces cerevisiae) with ATP regeneration facilitated by the phosphoenolpyruvate (PEP)/pyruvate kinase (PK) system[1]
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Sigma Aldrich Fine Chemicals Biosciences Glucose-6-phosphate Dehydr
Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).
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Medchemexpress LLC Glucose 6-phosphate dehydrogenase (yeast, recombinant) | 9001-40-5 | 500 U
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Glucose 6-phosphate dehydrogenase (yeast, recombinant) is the rate-limiting enzyme of the pentose phosphate pathway and a major source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems. It helps cells resist oxidative stress and regulates metabolic rates, holding potential for research in fields such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy.
- Rate-limiting enzyme of the pentose phosphate pathway
- Major source of NADPH in antioxidant pathways
- Involved in nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems
- Helps cells resist oxidative stress
- Regulates metabolic rates
- Potential for research in diabetes, endothelial dysfunction, cancer, and cardiomyopathy
- Classified as an enzyme and recombinant biochemical
- Considered an endogenous metabolite
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Medchemexpress LLC GLUCOSE-6-PHOSPHATE 5UG
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5000195531 GLUCOSE-6-PHOSPHATE 5UG
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Medchemexpress LLC EC-17 disodium salt | 910661-33-5 | 96.3% | 916.82 | 25 MG
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EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent that exhibits fluorescent properties within the visible light spectrum. Its maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively. It is intended for research use only.
- Folate receptor alpha (FRα) targeting contrast agent
- Fluorescent properties in the visible light spectrum
- Maximum excitation wavelength: 490 nm
- Maximum emission wavelength: 520 nm
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Alkali Scientific Ticarcillin Disodium Salt, 25 G
Ticarcillin Disodium Salt (25g) is an antibiotic used for the treatment of infections caused by a variety of bacteria, particularly Gram-negative organisms. This powder form is commonly used to prepare injectable solutions for intravenous administration. Ticarcillin disrupts the bacterial cell wall, leading to cell lysis and death. It is particularly effective against Pseudomonas aeruginosa, Klebsiella pneumoniae, and other resistant organisms. This 25g size is ideal for research and clinical use where larger quantities are needed for patient treatments or laboratory investigations. It is often used in combination with beta-lactamase inhibitors like Clavulanate to extend its spectrum of activity.
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Apexbio Technology LLC Balsalazide-disodium-diH2O
Balsalazide disodium dihydrate (CAS No 150399-21-6) is a prodrug commonly used in biomedical research focused on gastrointestinal conditions like ulcerative colitis Originating from efforts to reduce inflammation its mechanism involves releasing the active 5-aminosalicylic acid (5-ASA) in the colon which inhibits the production of inflammatory mediators such as leukotrienes and prostaglandins In vitro it shows activity in the nanomolar to low micromolar range indicating its efficacy in modulating inflammatory pathways Typical applications include studies using cell models like colon epithelial cells and animal studies aimed at understanding its therapeutic potential It is also explored in drug screening for new anti-inflammatory agents Experimental concentrations typically depend on the specific research design allowing flexibility in dosage depending on the experimental setup and objective
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Medchemexpress LLC DIPOTASSIUM GLYCYRRH 50 mg
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DIPOTASSIUM GLYCYRRH 50MG
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Medchemexpress LLC DIPOTASSIUM GLYCYRRH 50 mg
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DIPOTASSIUM GLYCYRRH 50MG
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Medchemexpress LLC DIPOTASSIUM TETRACHL 5G
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DIPOTASSIUM TETRACHL 5G
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Medchemexpress LLC MONO N-DESMETHYL DIS 10 mg
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MONO N-DESMETHYL DIS 10MG
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Medchemexpress LLC MONO N-DESMETHYL DIS 5 mg
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MONO N-DESMETHYL DIS 5MG
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Apexbio Technology LLC Demethylcantharidate-disodium
Demethylcantharidate disodium (CAS No 129-67-9) is a compound studied in the context of biomedical research specifically in pharmacological studies It originates from the traditional toxin cantharidin and operates by inhibiting protein phosphatases impacting pathways involved in cell growth and apoptosis Its in vitro activity is usually observed in the nanomolar to low micromolar range This compound is commonly applied in various cell models animal studies and drug screening protocols to explore its potential therapeutic effects Experimental concentrations typically depend on the specific research design
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