Sphingolipids
Medchemexpress LLC Lyso-PAF C-16 | 52691-62-0 | 99.8% | C24H52NO6P | 1 MG
Lyso-PAF C-16 is a substrate for lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). It selectively acetylates with arachidonic acid and is intended for research use only. It has demonstrated cytotoxicity against various human cancer cell lines, including A549, HCT15, SK-MEL-3, SKOV3, and XF498.
- Substrate for lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD)
- Selectively acetylates with arachidonic acid
- Intended for research use only
- Exhibits cytotoxicity against human A549 cells (ED50 5.5 μg/mL)
- Exhibits cytotoxicity against human HCT15 cells (ED50 5.4 μg/mL)
- Exhibits cytotoxicity against human SK-MEL-3 cells (ED50 5.4 μg/mL)
- Exhibits cytotoxicity against human SKOV3 cells (ED50 4.9 μg/mL)
- Exhibits cytotoxicity against human XF498 cells (ED50 4.9 μg/mL)
Medchemexpress LLC C16 ceramide-1-phosphate (d18:1/16:0) ammonium | 1246303-22-9 | 98.0% | 634.91 | C34H71N2O6P | 5 MG
C16 ceramide-1-phosphate (d18:1/16:0) (ammonium) is the ammonium salt of a bioactive sphingolipid, supplied as a purified research reagent for biochemical and cell biology studies of sphingolipid signaling and metabolism. It is provided as a characterized dry material for laboratory research use only and requires protected cold storage.
- High purity (98.0%).
- Molecular weight 634.91.
- Chemical formula C34H71N2O6P.
- Available in small pack sizes such as 5 MG.
- Storage: in solvent, -80°C (6 months) or -20°C (1 month); protect from light and store under nitrogen.
- Intended for biochemical assays and cell biology research; not for human use.
Medchemexpress LLC C24:1-ceramide (d18:1/24:1) | 54164-50-0 | MFCD02259277 | 99.9% | 648.10 g·mol⁻¹ | C42H81NO3 | 5 MG
C24:1-Ceramide (d18:1/24:1) is a long-chain sphingolipid commonly used in membrane biology, lipidomics, and formulation research. It functions as a reference standard and a structural lipid in liposome and lipid nanoparticle preparations for in vitro and analytical studies.
- High chemical purity reported by distributors (approximately 99.9%).
- Molecular formula C42H81NO3 and molecular weight ~648.10 g·mol-1.
- Solid form provided in small research pack sizes (mg scale) for analytical use.
- Suitable for membrane and lipidomics studies, and lipid nanoparticle formulation.
- Recommended storage at -20 °C to preserve stability.
- Supplied with CAS identifier 54164-50-0 for unambiguous reference.
Medchemexpress LLC C26 Sphingomyelin (d18:1/26:0)-d4 | 98.0% | 847.32 | 500 UG
C26 Sphingomyelin (d18:1/26:0)-d4 | 98.0% | 847.32 | 500 UG
Medchemexpress LLC Ceramide 3B | 178436-06-1 | 99.6% | 581.95 | 100 MG
Ceramide 3B is a ceramide 3 lipid class characterized by its aggregation behavior. It possesses various physiological functions, including acting as a penetration enhancer and an auxiliary emulsifier, contributing significantly to barrier function stability.
- Has aggregation behavior
- Can serve as a penetration enhancer
- Can serve as an auxiliary emulsifier
- Plays an important role in barrier function stability
Medchemexpress LLC C20 Ceramide (N-Arachidoyl-D-sphingosine) | 7344-02-7 | 99.1% | 594.01 | 25 MG
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a natural 20:0 ceramide and a N-acylsphingosine in which the ceramide N-acyl group is specified as eicosanoyl. C20 Ceramide acts as a key signal molecule mediating biological processes. It is for research use only and not sold to patients.
- Natural 20:0 ceramide
- N-acylsphingosine with eicosanoyl N-acyl group
- Acts as a key signal molecule
- Mediates cell growth, differentiation, senescence, and apoptosis
- For research use only
Medchemexpress LLC Sphingomyelin phosphodiesterase, Streptomyces sp. | 9031-54-3 | 10 U
Sphingomyelin phosphodiesterase, from Streptomyces sp., is a hydrolase involved in the sphingomyelin metabolism process. It catalyzes the conversion of sphingomyelin to phosphocholine and ceramide. This enzyme also plays a significant role in cellular differentiation, various immune and inflammatory responses, and intracellular cholesterol trafficking and metabolism.
- Hydrolase involved in sphingomyelin metabolism
- Catalyzes conversion of sphingomyelin to phosphocholine and ceramide
- Plays a significant role in cellular differentiation
- Important in various immune and inflammatory responses
- Involved in intracellular cholesterol trafficking and metabolism
- Intended for research use only
Medchemexpress LLC N-Octanoyl-D-erythro-sphingosine | 74713-59-0 | 98.0% | 425.69 | 100 MG
N-Octanoyl-D-erythro-sphingosine | 74713-59-0 | 98.0% | 425.69 | 100 MG
Cayman Chemical C8 CeramIde-1-phosphated185mg
C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C8 ceramide-1-phosphate are essentially the opposite of C8 ceramide; it induces DNA synthesis and cell division. The effects of C8 ceramide-1-phosphate can be attenuated by simultaneous treatment with C2 or C8 ceramide.{5183}
Medchemexpress LLC Sphingomyelin | 85187-10-6 | ≥99.0% | 50 MG
Sphingomyelin is a eukaryotic sphingolipid and a major constituent of cell membranes, particularly abundant in the myelin sheath that surrounds neuronal axons. It plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann-Pick disease.
- Major constituent of cell membranes
- Abundant in the myelin sheath
- Plays a role in cell processes
- Regulates inflammatory responses
- Involved in signal transduction
- Metabolism associated with central nervous system diseases and Niemann-Pick disease