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Sphingolipids

A class of lipids containing a backbone of sphingoid bases, a set of aliphatic amino alcohols that includes sphingosine, a long-chain amino alcohol.

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Sigma Aldrich Fine Chemicals Biosciences Ceramide phosphorylethanol5MG

Ceramide phosphorylethanolamine is a phosphosphingolipid. It maintains the structural framework of the plasma membrane aids in the formation and functioning of plasma membrane lipid rafts cell signaling and transduction events. Ceramide phosphorylethanolamine modulates various cellular processes like growth differentiation apoptosis and angiogenesis.

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2

Sigma Aldrich Fine Chemicals Biosciences Sphingomyelin chicken500MG

Sphingomyelin (SM) is a principal sphingolipid in mammalian cell membranes. Its biological functions have been studied.

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3

Sigma Aldrich Fine Chemicals Biosciences Colorimetric Sphingomyelin

Sphingomyelinase (SMase) or sphingomyelin phosphodiesterase catalyzes the hydrolytic cleavage of sphingolipid to phosphocholine and ceramide a second messenger involved in multiple cellular responses including the cellular response to stress. There are at least 5 types of SMases identified which are classified according to their cation dependence cellular location and pH optima for activity and include the acidic and neutral sphingomyelinase. Neutral SMases along with the acidic SMases are thought to be major contributors to the production of ceramide in response to cellular stress.

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