Steroids and derivatives
Medchemexpress LLC Estradiol (Standard) | 50-28-2 | MFCD00003693 | 100.0% | 25 MG
Estradiol (Standard) is an analytical standard of Estradiol, a major female sex hormone and steroid hormone. Intended for research and analytical applications, it can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. This compound is useful for research in cancers, neurodegenerative diseases, and neural tissue engineering.
- Analytical standard grade
- Reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments
- Applicable in techniques such as HPLC, GC, and MS
- Supports research in cancers, neurodegenerative diseases, and neural tissue engineering
- Up-regulates neural markers of human endometrial stem cells
- Promotes neural differentiation
Medchemexpress LLC β-Estradiol 17-acetate | 1743-60-8 | 99.9% | 1 ML
β-Estradiol 17-acetate is a metabolite of estradiol, designed for research use only in laboratory settings. It is provided for chemical synthesis and intended for use by experienced personnel in appropriately equipped facilities.
- Available in powder and pre-dissolved solution formats.
- Stable under recommended storage conditions, with specific guidance for powder and solvent forms.
- Highly soluble in DMSO for in vitro applications.
- Features established protocols for in vivo solubility using various solvent systems.
- Molecular formula C20H26O3 and molecular weight of 314.42.
- Typically appears as a white to off-white solid with a melting point of 119°C.
Medchemexpress LLC Alpha-Estradiol (Standard) | 57-91-0 | 99.93% | 25 MG
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol, intended for research and analytical applications. It is a weak estrogen and a 5α-reductase inhibitor used as a topical medication in the treatment of androgenic alopecia.
- Reference standard supplied assay
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Medchemexpress LLC Estradiol-d3 | 79037-37-9 | 98.6% | 5 MG
Estradiol-d3 is a deuterium-labeled form of Estradiol, a steroid sex hormone crucial for maintaining fertility and secondary sexual characteristics in females. It upregulates IL-6 expression via the estrogen receptor β (ERβ) pathway and is intended for research use only. This compound serves as a tracer and internal standard for quantitative analysis, leveraging the potential of deuteration to influence pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Deuteration influences drug pharmacokinetic and metabolic profiles
- Appears as a white to off-white solid
- Molecular weight: 275.40
- Chemical formula: C18H21D3O2
- Powder storage: -20°C for 3 years or 4°C for 2 years
- Solvent storage: -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO (50 mg/mL) and ethanol (20 mg/mL)
Cayman Chemical EstradIol CypIonate 1g
A synthetic estrogen; reduces estrogen-depletion induced spikes in basal tail temperature in ovariectomized wild-type, ERα-/-, and ERβ-/- mice at 0.1 mg/kg per day; increases the rate of pregnancy in cows induced to ovulate small dominant follicles; reduces edema and articular joint neutrophil infiltration in an ovariectomized mouse model of zymosan-induced arthritis
Sigma Aldrich Fine Chemicals Biosciences alpha Estradiol powder 98500MG
alpha Estradiol powder 98500MG
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 17-beta-D-g10MG
BETA7 beta-Estradiol 17-beta-D-g10MG
Cayman Chemical Ethynyl Estradiol
An estrogen receptor agonist (EC50 = 8.5 pM in a reporter assay using T47D cells); reduces serum cholesterol levels and femur bone mass and increases uterine mass in an OVX rat model of postmenopause at 0.1 mg/kg per day; has been found in wastewater effluent; prevents secondary sexual development in male fathead minnows and increases the numbers of intersex fish at 4 ng/l
Medchemexpress LLC Estradiol 17-(β-D-Glucuronide) sodium | 15087-02-2 | 98.9% | 50 MG
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. It functions as a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). This compound regulates and inhibits MRP8-mediated transport processes and can be used in studies related to intrahepatic cholestasis, as it induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats.
- Metabolite of natural estrogen
- Substrate of Oatp and Mrp2
- Regulates and inhibits MRP8-mediated transport processes
- Induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis
- Useful in studies related to intrahepatic cholestasis
- Solid, white to off-white appearance
- Molecular weight of 470.49
- Chemical formula C24H31NaO8
Sigma Aldrich Fine Chemicals Biosciences beta Estradiol 17 beta D g25MG
beta Estradiol 17 beta D g25MG
Selleck Chemical LLC Ethinyl Estradiol S1625-1g
Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills
Selleck Chemical LLC Dexamethasone S1322-10g
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects Dexamethasone induces autophagy and mitophagy Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients
Apexbio Technology LLC Cortisone acetate 50-04-4 100mg
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Sigma Aldrich Fine Chemicals Biosciences 6alpha-Methylprednisolone 21-hemisuccinate sodium salt lyophilized powder | 2375-03-3 | MFCD00152612 | 25MG
6alpha-Methylprednisolone 21-hemisuccinate sodium salt lyophilized powder | Purity: >=98.00% (TLC) | Mol Wt: 496.53 | 2375-03-3 | MFCD00152612 | 25MG
Selleck Chemical LLC Cortisone
Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress It suppresses the immune system thus reducing inflammation and attendant pain and swelling at the site of the injury