Steroids and derivatives
Medchemexpress LLC Octaarginine acetate | 98.33% | 1267.50 | 25 MG
Octaarginine acetate | 98.33% | 1267.50 | 25 MG
Medchemexpress LLC (S)-N-((3-Methyl-1-(methyl-d3)-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide | 2216712-66-0 | 99.23% | 600.67 | 500 UG
Elexacaftor-d3 (VX-445-d3) is the deuterium labeled form of Elexacaftor, designed as a tracer and internal standard for quantitative analysis using methods like NMR, GC-MS, or LC-MS. Deuterium substitution can impact the pharmacokinetic and metabolic profiles of drugs. Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector, which helps restore Phe508del CFTR protein function and has potential in treating cystic fibrosis. When combined with Tezacaftor and VX-770, it significantly enhances Phe508del CFTR protein processing, trafficking, and chloride transport.
- Tracer and internal standard for quantitative analysis
- Potential to influence pharmacokinetic and metabolic profiles of drugs
- Restores Phe508del CFTR protein function
- Potential to treat cystic fibrosis
- Enhances CFTR protein processing, trafficking, and chloride transport
Medchemexpress LLC Palonosetron-d3 hydrochloride | 1246816-81-8 | C19H22D3ClN2O | 1 MG
Palonosetron-d3 hydrochloride is the deuterium-labeled Palonosetron hydrochloride. Palonosetron hydrochloride acts as a 5-HT3 antagonist, primarily utilized for the prevention of acute, delayed, and overall chemotherapy-induced nausea and vomiting. Additionally, it exhibits moderate anti-flavivirus activity and potent anti-Zika virus activity in mammalian cells. Palonosetron hydrochloride also has antidepressant activity.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ramelteon-d3 | 1432057-38-9 | 99.0% | C16H18D3NO2 | 1 MG
Ramelteon-d3 (TAK-375-d3) is a deuterium-labelled Ramelteon, a potent and highly selective agonist of MT1/MT2 receptors. It has potential for insomnia research, consistently reducing sleep onset without residual effects or withdrawal symptoms. This compound can be used as a tracer and as an internal standard for quantitative analysis, with deuteration potentially affecting pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labelled Ramelteon
- Agonist of MT1/MT2 receptors
- Reduces sleep onset without residual effects
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Apexbio Technology LLC Ecdysterone 5289-74-7 20mg
Ecdysterone (CAS 5289-74-7) is a naturally occurring phytoecdysteroid predominantly isolated from Cyanotis arachnoidea It functions as an agonist of the ecdysone receptor modulating gene expression associated with growth protein synthesis and cellular differentiation Ecdysterone has been investigated for its anabolic effects without significant androgenic activity making it a subject of interest in muscle biology and metabolic research Soluble in methanol and DMSO this compound is suitable for a range of in vitro and in vivo studies examining molecular mechanisms underlying cellular growth and adaptation Store Ecdysterone in a cool dry and sealed environment
Medchemexpress LLC Betamethasone acetate | 987-24-6 | MFCD00867462 | 99.4% | 434.50 g/mol | C24H31FO6 | 5 MG
Betamethasone acetate is a synthetic glucocorticoid corticosteroid used as a research reagent and analytical standard in pharmacological and biochemical studies. It exhibits anti-inflammatory and immunosuppressive activity and is typically provided in small, measured quantities for laboratory assays.
- High purity appropriate for analytical and research applications.
- Anti-inflammatory and immunosuppressive activity for pharmacology studies.
- Available in small, measured quantities suitable for bench experiments.
- Supplied with supporting documentation such as COA and SDS.
- Soluble in common organic solvents for assay preparation.
Medchemexpress LLC Calcipotriol Impurity C | 113082-99-8 | 99.1% | C27H40O3 | 5 MG
Calcipotriol Impurity C is an impurity of Calcipotriol, which functions as a ligand for VDR-like receptors. This product is intended for research use only.
- Functions as a ligand for VDR-like receptors
- Target is VDR (Vitamin D Receptor)
- Soluble in DMSO
- Soluble in 10% DMSO >> 90% (20% SBE-β-CD in saline)
- Soluble in 10% DMSO >> 90% corn oil
- Store at 4°C, protected from light, under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light, under nitrogen
Cambridge Isotope Laboratories Hexamethylcyclotrisiloxane D3 (13C6 98%) 100 ug/mL in MTBE 1 2 mL
Hexamethylcyclotrisiloxane D3 (13C6 98%) 100 ug/mL in MTBE 1 2 mL
Cambridge Isotope Laboratories 11-Dehydrocorticosterone (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
11-Dehydrocorticosterone (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
Medchemexpress LLC Dexamethasone (Standard) | 50-02-2 | MFCD00064136 | 99.0% | 392.46 | 50 MG
Dexamethasone (Standard) is an analytical standard used in research and analytical applications. It acts as a glucocorticoid receptor agonist, significantly reducing the expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes. It is highly effective in managing COVID-19 infection and inhibits the production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
- Analytical standard for research and analytical applications
- Glucocorticoid receptor agonist
- Reduces expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes
- Effective in managing COVID-19 infection
- Inhibits production of exosomes containing inflammatory microRNA-155
- Used in qualitative, quantitative, and methodological research experiments (HPLC, GC, MS)
Cayman Chemical ResIbufogenIn 1mg
A cardiac glycoside that inhibits the Na+/K+-ATPase; exhibits cardiotonic, vasopressor, and respiratory stimulating actions in both animal and clinical models