Steroids and derivatives
Apexbio Technology LLC Ethinyl Estradiol 57-63-6 10mM (in 1mL DMSO)
Ethinyl Estradiol (57-63-6) is a small-molecule estrogen receptor agonist targeting intracellular estrogen receptors It is designed to activate these receptors thereby regulating transcription of estrogen-responsive genes and influencing reproductive biology and cell proliferation pathways Ethinyl Estradiol exerts its biological activity primarily through direct binding to estrogen receptors leading to the modulation of endocrine-regulated mechanisms Based on these pharmacological properties Ethinyl Estradiol holds research potential in studies of receptor-mediated responses endocrine regulation mechanisms synthetic hormone interactions drug interactions contraceptive mechanisms and hormone-dependent physiological processes
eMolecules Sodium cholate hydrate | 206986-87-0 | MFCD00150749 | 1g
Oakwood Chemical | Sodium cholate hydrate | 1g | 537719715 | 245680 | | 206986-87-0 | MFCD00150749 | 448.576 | C24H41NaO6
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Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 g/mol | C15H22ClN3O | 25 MG
Dopamine D2 receptor agonist-3 is a research compound characterized as a selective D2 receptor partial agonist and a D3 receptor antagonist. In vitro activity is reported with pEC50 8.3 at D2 and <5.5 at D3. In vivo, a 3 mg/kg (s.c.) dose demonstrated high brain penetration (brain:blood ratio ≈5.5) with Tmax ≈0.5 h. The compound is a solid with reported purity of 98.3% and molecular formula C15H22ClN3O.
- Selective D2 receptor partial agonist and D3 receptor antagonist.
- Reported pEC50 values: 8.3 (D2) and <5.5 (D3).
- High reported purity (98.3%).
- Solid form, suitable for research applications.
- Demonstrated brain penetration in vivo (3 mg/kg, s.c.; brain:blood ratio ~5.5).
- Available in small pack sizes, including 25 mg.
Selleck Chemical LLC Glycocholic acid S4958-25mg
Glycocholic acid (Cholylglycine Glycocholate) is a natural secondary bile acid involved in the emulsification of fats
Sigma Aldrich Fine Chemicals Biosciences CHENODEOXYCHOLIC ACID 97%
Chenodeoxycholic acid ≥97%, cas 474-25-9
Abcam Cholecalciferol (Vitamin D3), VDR activator, 5G
MW 384.6 Da, Purity >98%. VDR activator. Induces cell differentiation and shows antiproliferative effects. Metabolic calcifediol (ab142766) precursor. Shows antioxidant and anti-inflammatory effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
TARGETMOL CHEMICALS INC JUGLONE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg and bulk. Please contact Fisher for quotes. Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family including human Pin1 yeast Ess1/Ptf1 and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I II and III (IC50s = 2-7 uM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction both through Pin1-independent mechanisms. purity: 98%
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 10MG
GPI-1046 is a non-immunosuppressive immunophilin ligand used in research for its neuroprotective effects. It has been reported to upregulate glutamate transporter 1 (GLT1), reduce ethanol intake, and attenuate HIV-associated sensory neuropathy by modulating store-operated calcium entry. The compound is provided as a high-purity liquid (formula C20H28N2O4, MW ~360.45 g/mol).
- Non-immunosuppressive immunophilin ligand
- Reported neuroprotective activity
- Upregulates glutamate transporter 1 (GLT1)
- Attenuates HIV-associated sensory neuropathy via store-operated calcium entry modulation
- High purity (≈99.8%)
- Liquid appearance: colorless to light yellow
- Chemical formula C20H28N2O4; molecular weight ~360.45 g/mol
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month)
Selleck Chemical LLC Estradiol Cypionate S4046-50mg
Estradiol cypionate is the 17 -cyclopentylpropinate ester of estradiol which inhibits ET-1 synthesis via estrogen receptor