Steroids and derivatives
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol, (17α)- | 57-91-0 | 99.46% | 1 ML
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor, known for its use as a topical medication in the treatment of androgenic alopecia. This compound inhibits testosterone metabolism and attenuates LPS-induced inflammatory markers.
- Weak estrogen and 5α-reductase inhibitor
- Inhibits testosterone metabolism
- Attenuates LPS-induced inflammatory markers
- Molecular weight: 272.39
- Chemical formula: C18H24O2
- Appearance: White to off-white solid
- For research use only
Medchemexpress LLC Alpha-Estradiol (Standard) | 57-91-0 | 99.9% | 50 MG
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol, intended for research and analytical applications. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor used as a topical medication in the treatment of androgenic alopecia.
- Analytical standard for research and analytical applications
- Used in HPLC, GC, and MS experiments
- Weak estrogen and 5α-reductase inhibitor
- Solid appearance, white to off-white
- Stable under recommended storage conditions
Medchemexpress LLC Estradiol-d5 | 221093-45-4 | >99.7% | 5 MG
Estradiol-d5 is deuterium labeled Estradiol. Estradiol is a steroid sex hormone crucial for maintaining fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled compound.
Medchemexpress LLC Estradiol 3-methyl ether | 1035-77-4 | 99.9% | 286.41 | 5 MG
Estradiol 3-methyl ether, also known as 3-O-Methyl estradiol, is a synthetic estrogen. This compound has demonstrated the ability to disrupt microtubule networks in V79 cells with an EC50 of 9 μM, and it also inhibits cell proliferation. Furthermore, Estradiol 3-methyl ether has been observed to decrease serum cholesterol levels and contribute to body weight loss, indicating feminizing activity in an HFD murine model. It is intended for research use only.
- Functions as a synthetic version of the hormone estrogen.
- Can disrupt microtubule networks in V79 cells with an EC50 of 9 μM.
- Inhibits the proliferation of cells.
- Decreases serum cholesterol levels.
- Leads to an increase in body weight loss in HFD murine models.
- Exhibits feminizing activity in HFD murine models.
Medchemexpress LLC Fluorometholone (Standard) | 426-13-1 | 98.8% | 25 MG
Fluorometholone (Standard) is the analytical standard of Fluorometholone. This product is intended for research and analytical applications. Fluorometholone, a synthetic glucocorticoid, is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Medchemexpress LLC Fluorometholone (Standard) | 426-13-1 | MFCD00056461 | 98.8% | 5 MG
Fluorometholone (Standard) is the analytical standard of Fluorometholone, a synthetic glucocorticoid. It acts as a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. This product is intended for research and analytical applications, including research on dry eye.
- Analytical standard
- Glucocorticoid receptor agonist
- Anti-inflammatory properties
- Anti-allergic properties
- Used in qualitative, quantitative and methodological research experiments
- Applications include HPLC, GC, and MS
Selleck Chemical LLC Fluorometholone Acetate S4228-50mg
Fluorometholone Acetate (NSC 47438 Oxylone acetate) is a synthetic corticosteroid used in the treatment of steroid responsive inflammatory conditions of the eye
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 25 MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It potently inhibits carbonic anhydrase (CA) and has anti-inflammatory effects, making it suitable for external ocular inflammation research.
- Potently inhibits carbonic anhydrase (CA)
- Inhibits hCA-I with IC50 of 2.18 μM
- Inhibits hCA-II with IC50 of 17.5 μM
- Used in inflammation/immunology research
- Appears as a white to off-white solid
Medchemexpress LLC HY-N0555 5mg Medchemexpress, Escin IB CAS:26339-90-2 Purity:>98%
Medchemexpress, HY-N0555 5mg Escin IB CAS:26339-90-2 Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 99.99% | C18H23NO4S | 25 MG
Estrone O-sulfamate is a potent inhibitor of steroid sulfatase (STS). It exhibits inhibitory activity against STS in placental microsomes (P.M.) preparations and MCF-7 cells, with IC50 values of 18 nM and 0.83 nM, respectively. This compound is suitable for use in cancer research.
- Potent steroid sulfatase (STS) inhibitor
- Inhibits STS in placental microsomes (P.M.) preparations
- Inhibits STS in MCF-7 cells
- Suitable for cancer research
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 99.99% | C18H23NO4S | 100 MG
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. It has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. This compound can be used for the research of cancer.
- Potent steroid sulfatase (STS) inhibitor.
- Inhibitory activity in placental microsomes (P.M.) preparation with an IC50 of 18 nM.
- Inhibitory activity in MCF-7 cells with an IC50 of 0.83 nM.
- Suitable for cancer research.