Steroids and derivatives
Medchemexpress LLC Glycocholic acid | 475-31-0 | MFCD00065902 | 99.9% | 465.62 g/mol | C26H43NO6 | 10 MG
Glycocholic acid (Standard) is an analytical reference material of glycocholic acid intended for research and analytical applications. It provides a characterized, high-purity reference for assay calibration, method validation, and quantitative analysis.
- High purity (99.9%) suitable for analytical use.
- Molecular weight 465.62 g/mol and chemical formula C26H43NO6.
- Supplied as a 10 mg vial for small-scale analyses.
- Intended for assay development, calibration, and method validation.
- Certificate of analysis and safety data sheet available from the manufacturer.
Cambridge Isotope Laboratories Canonical Amino Acid Mix (unlabeled) 1 vial
Canonical Amino Acid Mix (unlabeled) 1 vial
Selleck Chemical LLC Glycocholic acid S4958-1g
Glycocholic acid (Cholylglycine Glycocholate) is a natural secondary bile acid involved in the emulsification of fats
AdipoGen Ecdysone
Chemical. CAS 3604-87-3. Formula C27H44O6. MW 464.6. Isolated from Ipomoea hederacea. Steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone. A member of the ecdysteroid family. Ecdysone receptor EcR agonist. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs sites of high expression to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins USP. Appears in many plants mostly as a protection agent toxins or antifeedants against herbivorous insects. Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides.
Cayman Chemical 17-EstradIol-d3 5mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS
Cayman Chemical EstradIol CypIonate 1g
A synthetic estrogen; reduces estrogen-depletion induced spikes in basal tail temperature in ovariectomized wild-type, ERα-/-, and ERβ-/- mice at 0.1 mg/kg per day; increases the rate of pregnancy in cows induced to ovulate small dominant follicles; reduces edema and articular joint neutrophil infiltration in an ovariectomized mouse model of zymosan-induced arthritis
Medchemexpress LLC Estradiol 3-methyl ether | 1035-77-4 | 99.9% | 286.41 | 10 MG
Estradiol 3-methyl ether is a synthetic estrogen that can disrupt microtubule networks in V79 cells with an EC50 of 9 μM and inhibit cell proliferation. Additionally, it decreases serum cholesterol levels and increases body weight loss, showing feminizing activity in an HFD murine model.
- Synthetic estrogen
- Disrupts microtubule networks
- Inhibits cell proliferation
- Decreases serum cholesterol levels
- Increases body weight loss
- Useful for biochemical assays
- Potential for research into microtubule modulation and cell proliferation
- Applicable in studies related to cholesterol regulation and weight management in relevant models
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 6-O-carboxy5MG
BETA beta-Estradiol 6-O-carboxy5MG
Medchemexpress LLC Hydrocortisone acepo 50mg | 74050-20-7 | 460.56 | C26H36O7 | 50 MG
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid supplied as a research-grade chemical standard for dermatological and pharmacological studies. The compound is supplied as a solid with high purity and is suitable for analytical and experimental applications.
- Potent topical glucocorticoid for dermatoses research.
- High purity (99.43%).
- Solid, white to off-white appearance.
- Molecular formula C26H36O7 and molecular weight 460.56.
- Available in multiple pack sizes, including 50 mg.
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Cortisone 21-acetate (Standard) | 50-04-4 | 99.4% | 402.48 | 100 MG
Cortisone acetate (Standard) is the analytical standard of Cortisone acetate, intended for research and analytical applications. It is an oxidized metabolite of Cortisol (a Glucocorticoid) and functions as an immunosuppressant and anti-inflammatory agent. At high concentrations, Cortisone acetate can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor.
- Grade of analytical standard, supplied as a reference standard assay.
- Commonly used in qualitative, quantitative, and methodological research experiments.
- Suitable for use in HPLC, GC, and MS.
- Acts as an immunosuppressant.
- Acts as an anti-inflammatory agent.
- Purity of 99.39%.
Medchemexpress LLC Dexamethasone acetate | 1177-87-3 | 98.2% | 434.50 | 1 G
Dexamethasone acetate is a glucocorticoid receptor agonist that significantly reduces expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes. It is effective in controlling COVID-19 infection and inhibits inflammatory microRNA-155 exosome production in lipopolysaccharide-induced macrophage responses.
- Functions as a glucocorticoid receptor agonist.
- Decreases CD11b, CD18, and CD62L expression on neutrophils and monocytes.
- Effective in controlling COVID-19 infection.
- Inhibits inflammatory microRNA-155 exosome production in macrophage responses.
- Targets: Glucocorticoid receptor, autophagy, mitophagy, SARS-CoV, and the complement system.
- Applicable in inflammation/immunology, endocrinology, and cancer research.
Apexbio Technology LLC Prednisone 53-03-2 1g
Prednisone is a synthetic glucocorticoid which functions primarily as an agonist of the glucocorticoid receptor (GR) Upon binding to the GR prednisone induces receptor translocation into the nucleus initiating the regulation of gene expression involved in inflammation immune responses and cellular proliferation Due to its immunosuppressive mechanism prednisone is widely used as an experimental tool in biomedical studies exploring inflammatory diseases autoimmune conditions and immune signaling pathways Structurally prednisone is a corticosteroid derivative characterized by specific modifications that affect its pharmacodynamics and bioavailability In laboratory settings prednisone assists researchers in dissecting glucocorticoid-mediated physiological and molecular events evaluating receptor-ligand interactions and examining downstream signaling mechanisms in various cell-based assays and animal models
Medchemexpress LLC Cortisone (Standard) | 53-06-5 | 98.5% | 360.44 | 100 MG
Cortisone (Standard) is the analytical standard of Cortisone, intended for research and analytical applications. It is an oxidized metabolite of Cortisol (a Glucocorticoid), and acts as an immunosuppressant and anti-inflammatory agent. This product is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS, and can partially intervene in the binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations.
- Analytical standard for Cortisone.
- Intended for research and analytical applications.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Acts as an immunosuppressant and anti-inflammatory agent.
Cayman Chemical Arachidonic Acid MaxSpec Sta
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Sigma Aldrich Fine Chemicals Biosciences Cholic acid from bovine and/or ovine, >=98% | 81-25-4 | MFCD00003672 | 100G
Cholic acid from bovine and/or ovine, >=98% | Purity: >=98% | Mol Wt: 408.57 | 81-25-4 | MFCD00003672 | 100G