Drug Standards
Medchemexpress LLC Mitotane | 53-19-0 | 99.9% | 320.04 | 500 MG
Mitotane (2,4'-DDD) is an antineoplastic agent used to research adrenocortical carcinoma. This isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT) primarily exerts its adrenocorticolytic effect through lipotoxicity induced by intracellular free cholesterol accumulation. It also has direct pituitary effects on corticotroph cells and can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation.
- Antineoplastic agent for adrenocortical carcinoma research.
- Exerts adrenocorticolytic effect via lipotoxicity.
- Direct pituitary effects on corticotroph cells.
- Induces CYP3A4 gene expression.
- Reduces H295R cell proliferation.
- Reduces TαT1 cell viability.
Medchemexpress LLC Mifepristone (Standard) | 84371-65-3 | 99.4% | 429.59 | 50 MG
Mifepristone (Standard) is an analytical standard intended for research and analytical applications. It acts as a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist. This standard is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist
- Suitable for HPLC, GC, and MS experiments
Medchemexpress LLC Raloxifene (hydrochloride) | 82640-04-8 | 99.8% | 510.04 | 100 MG
Raloxifene hydrochloride is a second generation selective and orally active estrogen receptor modulator. It produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue. It is for research use only and not sold to patients.
- Second generation selective and orally active estrogen receptor modulator
- Estrogen-agonistic effects on bone and lipid metabolism
- Estrogen-antagonistic effects on uterine endometrium and breast tissue
- For research use only
Medchemexpress LLC Methylprednisolone acetate | 53-36-1 | MFCD00200356 | 95.1% | 416.51 | 1 ML
Methylprednisolone acetate is a prednisolone derivative and a corticosteroid hormone. It is known to relieve pain and swelling associated with arthritis and other joint disorders in vivo. This product appears as a white to off-white solid.
- Corticosteroid hormone
- Relieves pain and swelling associated with arthritis
- Used in joint disorder research
- Targeted disease areas include neurological, eye or ear disease, inflammation or immune system disease, and pain
- Involves signaling pathways such as Immunology/Inflammation, Vitamin D Related/Nuclear Receptor, and Glucocorticoid Receptor
Medchemexpress LLC Mifepristone | 84371-65-3 | 99.9% | 429.59 | 1 ML
Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay. It was discovered as the first competitive progesterone antagonist, stimulating a search for more potent and selective antiprogestins.
- Progesterone receptor and glucocorticoid receptor antagonist
- Inhibits cell growth
- Potentiates doxorubicin-induced cytotoxicity in K562/R7 cells
- Reduces severity of EtOH withdrawal in vivo
Medchemexpress LLC (R)-Donepezil ((R)-E2020 free base) | 142698-19-9 | 99.91% ee.: 100.00% | 379.49 | 100 MG
(R)-Donepezil is an R-enantiomer of Donepezil, a specific and potent Acetylcholinesterase (AChE) inhibitor. It is provided as a solid, white to off-white in appearance.
- Specific and potent AChE inhibitor
- R-enantiomer of Donepezil
- Molecular weight: 379.49
- Purity: 99.91%
Medchemexpress LLC (R,1R)-Tenofovir amibufenamide | 1571076-37-3 | 98.9% | 490.49 | 1 MG
(R,1R)-Tenofovir amibufenamide is a drug intermediate that can be used for purifying a tenofovir prodrug. Tenofovir is a nucleoside acid reverse transcriptase inhibitor. It appears as a white to off-white solid and is for research use only.
- Can be used for purifying a tenofovir prodrug
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC Mifepristone (standard) | 84371-65-3 | 99.4% | 429.59 | 100 MG
Mifepristone (Standard) is an analytical standard of Mifepristone, also known as RU486. It functions as an antagonist for progesterone receptor (PR) and glucocorticoid receptor (GR), exhibiting IC50s of 0.2 nM and 2.6 nM respectively in in vitro assays. This product is designed for research and analytical applications.
- Intended for research and analytical applications
- Functions as a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
- Serves as a reference standard supplied assay
Medchemexpress LLC Zileuton | 111406-87-2 | MFCD00866097 | 99.61% | C11H12N2O2S | 50 MG
Zileuton is a potent and selective inhibitor of 5-lipoxygenase, commonly used in research for its antiasthmatic properties. This chemical appears as a white to off-white solid.
- Potent and selective inhibitor of 5-lipoxygenase
- Exhibits antiasthmatic properties
- For research use only
- Solid appearance
- Color: white to off-white
- Molecular weight: 236.30
- Melting/freezing point: 157-158°C
- Relative density: 1.401 g/cm³
Medchemexpress LLC Bromfenac sodium hydrate | 120638-55-3 | 99.9% | 200 MG
Bromfenac sodium hydrate is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. It can be used in ocular inflammation research.
- Potent and orally active inhibitor of COX.
- Can be used in ocular inflammation research.
- Available in solid and solution forms.
U.S. Pharmacopeia silver sulfadiazine | 22199-08-2 | 357.14 g/mol | 200MG
silver sulfadiazine | 22199-08-2 | 357.14 g/mol | 200MG
