Drug Standards
TARGETMOL CHEMICALS INC RUXOLITINIB 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ruxolitinib (INCB018424) is a potent and selective JAK1/2 inhibitor (IC50 3.3/2.8 nM) and is relatively less selective for JAK3 (IC50 322 nM). purity: 99%
Medchemexpress LLC Glycopyrrolate iodide-d3 (mixture of diastereomers) | 873295-32-0 | MFCD09952213 | >95.0% | 448.35 g/mol | C19H25D3INO3 | 1 MG
Glycopyrrolate iodide-d3 (mixture of diastereomers) is a deuterium-labeled isotopic analogue of glycopyrrolate supplied as the iodide salt in small research quantities. It is intended for use as an internal standard or analytical reference in biochemical, pharmacokinetic, and mass spectrometry applications. The material is supplied as a d3-labeled mixture of diastereomers at research-grade purity.
- Deuterium-labeled (d3) isotopologue for mass spectrometry and isotope-dilution assays.
- Iodide salt supplied as a mixture of diastereomers.
- Research quantity suitable for standard preparation and method development.
- Purity typically >95% (HPLC) as reported by isotope standard suppliers.
- Intended for use as an internal standard in quantitative analytical workflows.
- Store and handle according to the product safety data sheet.
Medchemexpress LLC Fexofenadine | 83799-24-0 | 99.8% | 1 ML
Fexofenadine is an orally active and nonsedative H1 receptor antagonist, suitable for research into allergic rhinitis and chronic idiopathic urticarial. It is provided as a 10 mM solution in DMSO.
- Active and nonsedative H1 receptor antagonist
- Can be used in allergic rhinitis research
- Can be used in chronic idiopathic urticarial research
- Purity of 99.8%
Sigma Aldrich Fine Chemicals Biosciences Misoprostol European Pharmacopoeia (EP) Reference Standard | 59122-46-2 | MFCD00274550 |
Misoprostol European Pharmacopoeia (EP) Reference Standard | Mol Wt: 382.53 | 59122-46-2 | MFCD00274550 |
Sigma Aldrich Fine Chemicals Biosciences Fluconazole European Pharmacopoeia (EP) Reference Standard | 86386-73-4 | MFCD00274549 |
Fluconazole European Pharmacopoeia (EP) Reference Standard | Mol Wt: 306.27 | 86386-73-4 | MFCD00274549 |
Sigma Aldrich Fine Chemicals Biosciences Loratadine British Pharmacopoeia (BP) Reference Standard | 79794-75-5 | MFCD00672869 |
Loratadine British Pharmacopoeia (BP) Reference Standard | Mol Wt: 382.88 | 79794-75-5 | MFCD00672869 |
Cayman Chemical Celecoxib Inhibitors
An NSAID and a COX-2 inhibitor (IC50 = 0.05 µM); selective for COX-2 over COX-1 (IC50 = 22.9 µM); induces apoptosis in BJAB and Jurkat cancer cells in a concentration-dependent manner; reduces blood glucose levels in a rat model of diabetes induced by STZ; reduces the latency to escape and the path length in the Morris water maze and also increases BDNF and TrkB protein levels in the hippocampus in the same model; inhibits production of IL-1β and TNF-α and reduces synovial fluid expression of the gene encoding MMP-3 in a rabbit model of osteoarthritis; increases serum levels of LDH, troponin-T, TNF-α, and CK-MB, markers of cardiotoxicity, in rats at 100 mg/kg per day
Cayman Chemical Arachidonoyl Ethanolamide Max
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
AdipoGen Enalaprilat
Chemical. CAS 76420-72-9. Formula C18H24N2O5. MW 348.4. Synthetic. Active metabolite enalapril. Nonsulfhydryl angiotensin-converting enzyme ACE inhibitor. Shown to improve cardiac preservation via bradykinin receptor and PKC without affecting ATP metabolism. Has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway. Increases PPARbeta/delta expression, without influence on PPARalpha and PPARgamma.
Medchemexpress LLC Lenalidomide-PEG1-azide | 2185795-67-7 | MFCD34469882 | 95.8% | 386.36 g·mol⁻¹ | C17H18N6O5 | 5 MG
Lenalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that combines a lenalidomide-derived cereblon-binding moiety with a short PEG1 linker terminating in an azide. It is intended as a building block for PROTAC construction and for bioorthogonal conjugation using copper-catalyzed or strain-promoted azide-alkyne cycloaddition.
- Terminal azide enables CuAAC and SPAAC click chemistry.
- Lenalidomide-derived cereblon ligand for E3 ligase recruitment.
- Short PEG1 linker provides minimal steric bulk.
- High chemical purity suitable for research use.
- Molecular weight 386.36 g·mol⁻¹; CAS 2185795-67-7.
- Available in small-scale quantities for synthesis and screening.
Medchemexpress LLC Spironolactone (Standard) | 52-01-7 | 98.6% | 100 MG
Spironolactone (Standard) serves as the analytical standard for Spironolactone. It is designed for research and analytical applications. Spironolactone (SC9420) is an orally active antagonist of the aldosterone mineralocorticoid receptor, with an IC50 of 24 nM. It also acts as a potent antagonist of the androgen receptor, exhibiting an IC50 of 77 nM. Furthermore, Spironolactone has been shown to promote autophagy in podocytes.
- Intended for research and analytical applications
- Analytical standard for Spironolactone
- Orally active aldosterone mineralocorticoid receptor antagonist (IC50 of 24 nM)
- Potent antagonist of androgen receptor (IC50 of 77 nM)
- Promotes autophagy in podocytes
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications