Drug Standards
Medchemexpress LLC Triamcinolone | 124-94-7 | 99.82% | 500 MG
Triamcinolone is a long-acting corticosteroid that exerts anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory, and neuroprotective effects by binding to glucocorticoid receptors. It is used to relieve various dermatitis, immune diseases, and ocular diseases.
- Long-acting corticosteroid
- Anti-inflammatory effects
- Anti-oedematous effects
- Anti-proliferative effects
- Anti-angiogenetic effects
- Immunomodulatory effects
- Neuroprotective effects
- Binds to glucocorticoid receptors
- Relieves various dermatitis
- Relieves immune diseases
- Relieves ocular diseases
Cayman Chemical Pantoprazole 1g
A proton pump inhibitor; inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles (IC50 = 6.8 µM); reduces basal gastric acid secretion in pylorus-ligated rats (ED50 = 1.3 mg/kg); inhibits mepirizole-induced increases in gastric acid secretion in an anesthetized rat model of gastric fistula (ED50 = 0.8 mg/kg); inhibits formation of mepirizole-induced duodenal lesions in rats (ED50 = 0.5 mg/kg)
Medchemexpress LLC Fluticasone (propionate) | 80474-14-2 | 99.8% | 100 MG
Fluticasone propionate is a potent topical anti-inflammatory corticosteroid and a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. It shows little or no activity at other steroid receptors and also has anti-viral activity.
- Potent topical anti-inflammatory corticosteroid.
- Selective glucocorticoid receptor agonist (KD of 0.5 nM).
- Shows little or no activity at other steroid receptors.
- Has anti-viral activity.
- Inhibits TNFα-induced E-selectin expression (IC50 of 1 nM).
- Targets: Glucocorticoid Receptor, Endogenous Metabolite, Enterovirus, and ADC Payload.
Medchemexpress LLC Detomidine hydrochloride | 90038-01-0
Detomidine hydrochloride is an imidazole derivative and a potent α2-adrenergic agonist that produces dose-dependent analgesic effects. This product is for research use only and has not been fully validated for medical applications.
- Potent α2-adrenergic agonist
- Produces dose-dependent analgesic effects
- Imidazole derivative
- Targets adrenergic receptor
- Involves GPCR/G protein and neuronal signaling pathways
- Molecular formula: C12H15CIN2
- Molecular weight: 222.71
Medchemexpress LLC Fluticasone propionate-d5 | 1093258-28-6 | 91.7% | 1 MG
Fluticasone propionate-d5 is a deuterium labeled form of Fluticasone propionate. It is a potent topical anti-inflammatory corticosteroid and a selective glucocorticoid receptor agonist with an absolute affinity (KD) of 0.5 nM. It exhibits little to no activity at other steroid receptors and possesses anti-viral activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ganoderic acid D | 108340-60-9 | 514.65 | 1 ML
Ganoderic acid D is a highly oxygenated tetracyclic triterpenoid and a major active component of *Ganoderma lucidum*. It upregulates SIRT3 protein expression, inducing deacetylated cyclophilin D (CypD) by SIRT3. This compound inhibits energy reprogramming in colon cancer cells, including glucose uptake, lactate production, pyruvate, and acetyl-coenzyme production. Ganoderic acid D also induces apoptosis in HeLa human cervical carcinoma cells and inhibits the growth of numerous cancer cell lines.
- Upregulates SIRT3 protein expression and induces deacetylated cyclophilin D (CypD).
- Inhibits energy reprogramming in colon cancer cells.
- Induces apoptosis in human cervical carcinoma cells.
- Inhibits the growth of various cancer cell lines.
- Exhibits anti-inflammatory activity.
- Induces G2/M phase arrest.
Medchemexpress LLC (R)-Ketorolac | 66635-93-6 | 99.65% | 50 MG
(R)-Ketorolac is an orally active inhibitor of Cdc42 and Rac1 GTPases. It has been shown to alter ovarian cancer cell behaviors crucial for invasion and metastasis and can ameliorate cancer-associated cachexia.
- Orally active Cdc42 and Rac1 inhibitor.
- Inhibits GTPase.
- Alters ovarian cancer cell behaviors critical for invasion and metastasis.
- Ameliorates cancer-associated cachexia.
Medchemexpress LLC Fexofenadine (hydrochloride) | 153439-40-8 | MFCD00865710 | 99.9% | 10 MM 1 ML
Fexofenadine hydrochloride is an orally active and nonsedative H1 receptor antagonist. It is used in allergic rhinitis and chronic idiopathic urticarial research.
- Orally active H1 receptor antagonist
- Non-sedative
- Used in allergic rhinitis research
- Used in chronic idiopathic urticarial research
Medchemexpress LLC Dutasteride impurity 1 | 103335-41-7 | MFCD00876749 | 25mg
Dutasteride Impurity 1 is an impurity of Dutasteride (HY-13613)
Sigma Aldrich Fine Chemicals Biosciences Casticin United States Pharmacopeia (USP) Reference Standard | 479-91-4 | MFCD00210481 | 25MG
Casticin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 374.34 | 479-91-4 | MFCD00210481 | 25MG
Medchemexpress LLC Lenalidomide-4-aminomethyl hydrochloride | 444289-05-8 | 90.88% | 309.75 | 25 MG
Lenalidomide-4-aminomethyl hydrochloride is a cereblon (CRBN) ligand derived from Lenalidomide, designed to recruit the CRBN protein. It serves as a component that can be linked to a target protein ligand via a linker, thereby forming a PROTAC. This compound is intended for research use only.
- Cereblon (CRBN) ligand: Functions as a Lenalidomide-based cereblon ligand, facilitating the recruitment of the CRBN protein.
- PROTAC formation: Can be connected to a ligand for a protein by a linker to create a PROTAC (proteolysis-targeting chimera).
- Protein degradation mechanism: PROTACs, formed with this compound, utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Research applications: Suitable for various research purposes, particularly in areas involving protein degradation and E3 ligase ligands.
Apexbio Technology LLC Tenofovir hydrate 206184-49-8 10mg
Tenofovir hydrate (CAS 206184-49-8) is a small-molecule inhibitor targeting HIV-1 reverse transcriptase It is designed to competitively inhibit reverse transcriptase thereby blocking viral DNA synthesis and replication Tenofovir hydrate exerts its biological activity primarily through intracellular phosphorylation and subsequent inhibition of HIV-1 reverse transcriptase In in vitro studies Tenofovir hydrate demonstrates inhibitory activity with reported EC50 values ranging from 29 fmol per 10 6 cells at low viral input (MOI 1) to 411 fmol per 10 6 cells at higher inputs (MOI 100) Based on these pharmacological properties Tenofovir hydrate holds research potential in the study of viral therapy resistance mechanisms and prophylactic intervention concerning HIV-1 and HBV infections
Medchemexpress LLC 2,6-piperidinedione, 3-(4-bromo-7-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- | 2438239-34-8 | MFCD34576717 | 97.0% | 341.13 g/mol | C13H10BrFN2O3 | 25 MG
Lenalidomide-4-Br-7-fluoro is a synthetic derivative of lenalidomide bearing bromine and fluorine substituents on the benzyl ring. It is intended for research use and is employed as a ligand for E3 ubiquitin ligases and in PROTAC-related studies. Molecular formula C13H10BrFN2O3; molecular weight 341.13 g/mol.
- Derivative of lenalidomide with bromine and fluorine substituents.
- Used as an E3 ligase ligand in PROTAC design and target degradation research.
- Certificate of analysis reports purity of 97.0% (NMR).
- Supplied as a powder with recommended storage: -20°C (3 years) or 4°C (2 years).
- Molecular weight 341.13 g/mol and molecular formula C13H10BrFN2O3.
- For research use only; not for diagnostic or therapeutic use.
Sigma Aldrich Fine Chemicals Biosciences Drospirenone for peak identification European Pharmacopoeia (EP) Reference Standard | 67392-87-4 | MFCD00867350 |
Drospirenone for peak identification European Pharmacopoeia (EP) Reference Standard | Mol Wt: 366.49 | 67392-87-4 | MFCD00867350 |