Drug Standards
Medchemexpress LLC Elubrixin tosylate | 960495-43-6 | 98.1% | 635.51 | 1 ML
Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible, and orally active CXCR2 antagonist and an IL-8 receptor antagonist. It inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM), making it suitable for research into inflammatory diseases.
- Potent and selective CXCR2 and IL-8 receptor antagonist
- Inhibits neutrophil CD11b upregulation
- Inhibits neutrophil shape change
- Orally active and reversible
- Potential for inflammatory diseases research
Medchemexpress LLC Lenalidomide-C4-NH2 50mg | 2435715-90-3 | 351.83 g/mol | C17H22ClN3O3 | 50 MG
Lenalidomide-C4-NH2 hydrochloride is a lenalidomide-derived cereblon (CRBN) ligand supplied as the hydrochloride salt for research use. It is used as a CRBN-recruiting moiety in targeted protein degradation (PROTAC) design and in biochemical and cell-based assays.
- Serves as a cereblon (CRBN) binding ligand for recruitment of E3 ubiquitin ligase.
- Provided as the hydrochloride salt for improved handling and solubility.
- Typical purity ~95.8%, suitable for research applications.
- Molecular weight 351.83 g/mol and formula C17H22ClN3O3.
- Soluble in DMSO and compatible with linker conjugation chemistries for PROTAC synthesis.
- Available in multiple pack sizes for research-scale use.
Selleck Chemical LLC Tazarotene 10mg 118292-40-3 AGN190168
Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Flumazenil acid | 84378-44-9 | MFCD08061420 | 100.0% | 275.24 g/mol | C13H10FN3O3 | 50 MG
Flumazenil acid is the primary metabolite of flumazenil and is supplied as a solid research reference standard for analytical and pharmacological studies. It is intended for use in metabolite profiling, impurity characterization, and method development.
- Primary metabolite of flumazenil.
- Used as a reference standard for analytical and metabolic studies.
- High purity suitable for research (99.96%).
- Molecular weight 275.24 g/mol; formula C13H10FN3O3.
- Off-white to light yellow solid with recommended cold storage for stability.
- Documentation available for analytical use, including data sheet, COA, and SDS.
Sigma Aldrich Fine Chemicals Biosciences Orphenadrine hydrochloride European Pharmacopoeia (EP) Reference Standard | 341-69-5 | MFCD00012480 |
Orphenadrine hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 305.84 | 341-69-5 | MFCD00012480 |
Medchemexpress LLC Enzastaurin | 170364-57-5 | MFCD11040980 | >98.0% | 515.61 g/mol | C32H29N5O2 | 100 MG
Enzastaurin (LY317615) is a small-molecule research reagent that selectively inhibits protein kinase C beta (PKCβ). It is supplied as a powder for laboratory use and is commonly used in kinase inhibition and cell-signaling studies.
- Potent PKCβ inhibitor with IC50 = 6 nM.
- Shows 6- to 20-fold selectivity over PKCα, PKCγ, and PKCε.
- Molecular formula C32H29N5O2 and molecular weight 515.61 g/mol.
- Provided as a powder suitable for preparing stock solutions.
- Used for kinase signaling, apoptosis, and autophagy research applications.
U.S. Pharmacopeia Ethacrynic acid, 58-54-8, MFCD00056693, 200 mg
Empirical Formula (Hill Notation): C13H12Cl2O4, Molecular Weight: 303.14, Synonym: (2,3-Dichloro-4-[2-methylenebutyryl]phenoxy)acetic acid.
Sigma Aldrich Fine Chemicals Biosciences Chlorpromazine hydrochloride | 69-09-0 | MFCD00012654 | 5g
Chlorpromazine hydrochloride | Purity: 98% | MW: 355.33 | 69-09-0 | MFCD00012654 | 5g
Sigma Aldrich Fine Chemicals Biosciences Isoprenaline hydrochloride European Pharmacopoeia (EP) Reference Standard | 51-30-9 | MFCD00012603 |
Isoprenaline hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 247.72 | 51-30-9 | MFCD00012603 |
Selleck Chemical LLC SN-38 50mg 86639-52-3
SN-38 is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC (R)-Ketorolac | 66635-93-6 | 99.7% | 25 MG
(R)-Ketorolac is an orally active Cdc42 and Rac1 inhibitor. It inhibits GTPase and alters ovarian cancer cell behaviors critical for invasion and metastasis. It also ameliorates cancer-associated cachexia.
- Inhibits growth factor-dependent activation of Cdc42 and Rac1 in SKOV3ip cells with EC50 values of 2.577 μM for Cdc42 and 0.587 μM for Rac1.
- Decreases numbers and length of filopodia in SKOV3ip cells and reduces their adherence to fibronectin and collagen.
- Ameliorates cancer-associated cachexia and prolongs survival of C26 tumor-bearing mice.
- Prevented C26-induced T-lymphopenia.