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Filtered Search Results
eMolecules 6268-49-1 | Dabcyl acid | Ambeed269.304 | C15H15N3O2 | 97.000 | CN(C)c1ccc(cc1)N=Nc1ccc(cc1)C(O)=O | 1g | 600839201
Dabcyl acid | Ambeed | 6268-49-1269.304 | C15H15N3O2 | 97.000 | CN(C)c1ccc(cc1)N=Nc1ccc(cc1)C(O)=O | 1g | 600839201
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Medchemexpress LLC NI-57 | 1883548-89-7 | 99.4% | 383.42 | 50 MG
Small and Specialty Supplier Partner
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NI-57 is a chemical probe and an inhibitor of the bromodomain and plant homeodomain finger-containing (BRPF) family of proteins. It exhibits IC50s of 3.1, 46, and 140 nM for BRPF1, BRPF2 (BRD1), and BRPF3, respectively. It is intended for research use only and not for sale to patients.
- Inhibits BRPF family proteins with varying IC50s (3.1 nM for BRPF1, 46 nM for BRPF2 (BRD1), and 140 nM for BRPF3).
- Binds to the BRD of BRPF1 with a Kd of 31 ± 2 nM, BRD1 with a Kd of 110 ± 13 nM, and BRPF3 with a Kd of 410 ± 47 nM.
- Shows less activity on BRD9 (IC50, 520 nM) and BRD4 (BD1) (IC50, 3700 nM), and TRIM24 (IC50, 1600 nM).
- Inhibits BRPF BRDs in the nucleus.
- Reduces CCL-22 gene expression by 27.7 ± 9.4% at 10 μM.
- Has favorable oral bioavailability in mice.
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eMolecules 19005-93-7 | 1H-Indole-2-carbaldehyde | Synthonix | MFCD03001425 | 145.161 | C9H7NO | 95.000 | O=Cc1cc2ccccc2[nH]1 | 250mg | 779538923
1H-Indole-2-carbaldehyde | Synthonix | 19005-93-7 | MFCD03001425 | 145.161 | C9H7NO | 95.000 | O=Cc1cc2ccccc2[nH]1 | 250mg | 779538923
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eMolecules 1187055-61-3 | tert-butyl N-[5-(trifluoromethyl)pyridin-3-yl]carbamate | Pharmablock | MFCD22201173 | 262.232 | C11H13F3N2O2 | 97.000 | CC(C)(C)OC(=O)Nc1cncc(c1)C(F)(F)F | 50mg | 586139652
tert-butyl N-[5-(trifluoromethyl)pyridin-3-yl]carbamate | Pharmablock | 1187055-61-3 | MFCD22201173 | 262.232 | C11H13F3N2O2 | 97.000 | CC(C)(C)OC(=O)Nc1cncc(c1)C(F)(F)F | 50mg | 586139652
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eMolecules 86454-13-9 | 2-Hydroxy-6-methylisonicotinic acid | Ambeed | MFCD02682019 | 153.137 | C7H7NO3 | 98.000 | Cc1cc(cc(O)n1)C(O)=O | 250mg | 525150797
2-Hydroxy-6-methylisonicotinic acid | Ambeed | 86454-13-9 | MFCD02682019 | 153.137 | C7H7NO3 | 98.000 | Cc1cc(cc(O)n1)C(O)=O | 250mg | 525150797
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eMolecules 175277-11-9 | 3-tert-Butyl-1-methylpyrazole-5-carboxylic Acid | Ambeed | MFCD00173812 | 182.223 | C9H14N2O2 | 97.000 | Cn1nc(cc1C(O)=O)C(C)(C)C | 250mg | 552725212
3-tert-Butyl-1-methylpyrazole-5-carboxylic Acid | Ambeed | 175277-11-9 | MFCD00173812 | 182.223 | C9H14N2O2 | 97.000 | Cn1nc(cc1C(O)=O)C(C)(C)C | 250mg | 552725212
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eMolecules 58509-59-4 | ChemScene | 67-Dihydro-8(5H)-quinolinone oxime | 100mg | 686113637 | CS-M0359 | MFCD18207122 | 162.192 | C9H10N2O
ChemScene | 67-Dihydro-8(5H)-quinolinone oxime | 100mg | 686113637 | CS-M0359 | 58509-59-4 | MFCD18207122 | 162.192 | C9H10N2O
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eMolecules 1251009-79-6 | ChemScene | tert-Butyl (2-bromo-4567-tetrahydrobenzo[d]thiazol-6-yl)carbamate | 100mg | 572257587 | CS-0038758 | MFCD13195380 | 333.24 | C12H17BrN2O2S
Medchem Express | hSMG-1 inhibitor 11j | 5mg | 591911963 | HY-124719 | 1402452-15-6 | 566.080 | C27H28ClN7O3S
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eMolecules 1438559-55-7 | ChemScene | 1-(5-Chloroquinolin-8-yl)ethan-1-one | 100mg | 569146510 | CS-0130045 | MFCD28338884 | 205.64 | C11H8ClNO
ChemScene | 2-(Difluoromethyl)-3-(4455-tetramethyl-132-dioxaborolan-2-yl)pyridine | 100mg | 768994170 | CS-0616432 | 1951411-51-0 | 255.070 | C12H16BF2NO2
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eMolecules 3724-10-5 | Ambeed | 2-(Methylthio)benzoic acid | 1g | 600846922 | A746023 | MFCD00029934 | 168.21 | C8H8O2S
Medchem Express | PF-01247324 | 5mg | 446256731 | HY-101383 | 875051-72-2 | MFCD28156579 | 330.590 | C13H10Cl3N3O
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eMolecules 496863-48-0 | Ambeed | 1-(2-(Methylthio)pyrimidin-4-yl)ethanone | 100mg | 525161561 | A264495 | MFCD09263472 | 168.21 | C7H8N2OS
Medchem Express | TfR-T12 (TFA) | 5mg | 582658922 | HY-P2297A | | 1604.770 | C73H100F3N19O17S
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Chem Service Inc P-NITROANILINE SOLUTION 1ML
This item has a minimum order quantity of 3 per supplier requirements
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eMolecules 1122-72-1 | Ambeed | 6-Methyl-2-pyridinecarboxaldehyde | 5g | 552579941 | A143143 | MFCD00006291 | 121.139 | C7H7NO
Ambeed | (35-Difluoro-4-(methoxycarbonyl)phenyl)boronic acid | 100mg | 572955430 | A425854 | 1190989-09-3 | MFCD16295262 | 215.950 | C8H7BF2O4
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eMolecules 20924-05-4 | Thymine-1-acetic acid | Ambeed | MFCD00274250 | 184.151 | C7H8N2O4 | 98.000 | Cc1cn(CC(O)=O)c(=O)[nH]c1=O | 250mg | 521409282
Thymine-1-acetic acid | Ambeed | 20924-05-4 | MFCD00274250 | 184.151 | C7H8N2O4 | 98.000 | Cc1cn(CC(O)=O)c(=O)[nH]c1=O | 250mg | 521409282
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 84332-06-9 | ChemScene | 4-Methoxy-2-(methylthio)pyrimidine-5-carboxylic acid | 250mg | 569146362 | CS-0112787 | MFCD02671593 | 200.21 | C7H8N2O3S
ChemScene | 4-Methoxy-2-(methylthio)pyrimidine-5-carboxylic acid | 250mg | 569146362 | CS-0112787 | 84332-06-9 | MFCD02671593 | 200.210 | C7H8N2O3S
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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