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Filtered Search Results
Medchemexpress LLC 3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-dimethylpropan-1-amine | 1219962-49-8 | 98.8% | 397.519 g·mol⁻¹ | C23H31N3O3 | 25MG
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AT791 is a small-molecule, orally bioavailable inhibitor of Toll-like receptors TLR7 and TLR9. It blocks DNA-TLR9 interaction in vitro and suppresses cytokine responses such as IL-6 and type I interferon in human and mouse cells, making it suitable for immunology and autoimmune research.
- Orally bioavailable small-molecule inhibitor of TLR7 and TLR9.
- Blocks DNA-TLR9 interaction and inhibits TLR-mediated signaling in vitro.
- Potent activity against TLR9 (low-nanomolar IC50) and weaker activity against TLR7.
- High-purity solid with good solubility in DMSO (~10 mM) for assay preparation.
- Appropriate for cellular and in vivo studies of TLR-driven immune responses.
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eMolecules Ambeed / Indane-5-carboxylic Acid / 100mg / 589771025 / A347938 / / 65898-38-6 / MFCD04038659 / 162.188 / C10H10O2
Ambeed / Indane-5-carboxylic Acid / 100mg / 589771025 / A347938 / / 65898-38-6 / MFCD04038659 / 162.188 / C10H10O2
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eMolecules JW PharmLab LLC / (R)-2-(1-tert-Butoxycarbonylamino-ethyl)-benzoic acid / 500mg / 699865714 / 15R0962 / 97.000 / 2380510-87-0 / [null] / 265.309 / C14H19NO4
JW PharmLab LLC / (R)-2-(1-tert-Butoxycarbonylamino-ethyl)-benzoic acid / 500mg / 699865714 / 15R0962 / 97.000 / 2380510-87-0 / [null] / 265.309 / C14H19NO4
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eMolecules Ambeed / 12-Benzisoxazole-3-acetic Acid / 5g / 506388770 / A165286 / / 4865-84-3 / MFCD02180388 / 177.159 / C9H7NO3
Ambeed / 12-Benzisoxazole-3-acetic Acid / 5g / 506388770 / A165286 / / 4865-84-3 / MFCD02180388 / 177.159 / C9H7NO3
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eMolecules Ambeed / 4-Methoxy-3-(3-morpholinopropoxy)benzonitrile / 1g / 721602024 / A1638947 / / 675126-28-0 / MFCD23134620 / 276.336 / C15H20N2O3
Ambeed / 4-Methoxy-3-(3-morpholinopropoxy)benzonitrile / 1g / 721602024 / A1638947 / / 675126-28-0 / MFCD23134620 / 276.336 / C15H20N2O3
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Medchemexpress LLC Abemaciclib (LY2835219) | 1231929-97-7 | MFCD22665744 | 99.9% | 506.6 g/mol | C27H32F2N8 | 10 MG
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Analytical standard of Abemaciclib (LY2835219) provided for research and analytical applications. The material is intended as a reference standard for assay calibration, method validation, and LC-MS/HPLC analysis, with a high purity specification to support reproducible analytical results.
- Intended for research and analytical applications as an analytical reference standard.
- High purity suitable for LC-MS and HPLC assay calibration (manufacturer-listed purity ≈99.9%).
- Useful for method validation, calibration, and quantitative analysis of abemaciclib.
- Small pack sizes available for analytical workflows (e.g., 10 mg).
- Chemical identifiers: CAS 1231929-97-7; molecular formula C27H32F2N8.
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eMolecules AstaTech / 4-(OXETAN-3-YL)BENZOIC ACID / 0.25g / 233630663 / 85371 / 95.000 / 1554650-83-7 / MFCD26521371 / 178.187 / C10H10O3
AstaTech / 4-(OXETAN-3-YL)BENZOIC ACID / 0.25g / 233630663 / 85371 / 95.000 / 1554650-83-7 / MFCD26521371 / 178.187 / C10H10O3
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eMolecules Ambeed / 6-(Methoxymethyl)pyrimidin-4-ol / 100mg / 642079724 / A118793 / / 3122-78-9 / MFCD16630187 / 140.142 / C6H8N2O2
Ambeed / 6-(Methoxymethyl)pyrimidin-4-ol / 100mg / 642079724 / A118793 / / 3122-78-9 / MFCD16630187 / 140.142 / C6H8N2O2
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eMolecules Ambeed / 1-Benzoylpiperidine-4-carboxylic acid / 250mg / 490490006 / A104256 / / 5274-99-7 / MFCD00040747 / 233.267 / C13H15NO3
Ambeed / 1-Benzoylpiperidine-4-carboxylic acid / 250mg / 490490006 / A104256 / / 5274-99-7 / MFCD00040747 / 233.267 / C13H15NO3
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Medchemexpress LLC Ibezapolstat | 1275582-97-2 | 98.0% | 10 MG
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Ibezapolstat (ACX-362E) is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor developed for the research of C. difficile infection (CDI). It is for research use only.
- Inhibits DNA pol IIIC from aerobic and low G+C Gram-positive bacteria
- Active against a broad spectrum of C. difficile pathogens
- MIC range of 1-8 μg/mL for 104 C. difficile clinical isolates
- Poorly absorbed and nontoxic in hamster C. difficile-associated disease model
- Strong anti-C. difficile properties in hamster CDAD model, protecting infected animals for up to 5 days
- Appears as a white to off-white solid
- Soluble in DMSO (62.5 mg/mL)
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC Lapachol | 84-79-7 | 100 MG
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Lapachol is a natural naphthoquinone known for its diverse biological activities. It functions as an orally active and potent DHODH inhibitor, demonstrating immunosuppressive effects on lymphocytes by blocking DHODH activity and inhibiting pyrimidine synthesis. Furthermore, Lapachol acts as a vitamin K antagonist, exhibiting antitumor activity by inhibiting DNA and RNA synthesis in neoplastic cells, and also possesses anti-Leishmania properties.
- Lapachol is a natural naphthoquinone.
- It is an orally active, potent DHODH inhibitor.
- Lapachol exhibits immunosuppressive activity on lymphocytes by blocking DHODH activity and inhibiting pyrimidine synthesis.
- It acts as a vitamin K antagonist with antitumor activity.
- Lapachol can inhibit DNA and RNA synthesis in neoplastic cells.
- It possesses anti-Leishmania activity.
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Medchemexpress LLC HY-N2389 5mg Medchemexpress, Formosanin C CAS:50773-42-7 Purity:>98%
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Medchemexpress, HY-N2389 5mg Formosanin C CAS:50773-42-7 Formosanin C is a diosgenin saponin isolated from Paris formosana Hayata and an immunomodulator with antitumor activity. Formosanin C induces apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Ambeed / Boc-Phg-OH / 25g / 525148246 / A242093 / / 2900-27-8 / MFCD00065588 / 251.282 / C13H17NO4
Ambeed / Boc-Phg-OH / 25g / 525148246 / A242093 / / 2900-27-8 / MFCD00065588 / 251.282 / C13H17NO4
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eMolecules Ambeed / 1H-Imidazole-2-carbaldehyde / 5g / 552531270 / A110938 / / 10111-08-7 / MFCD00003544 / 96.089 / C4H4N2O
Ambeed / 1H-Imidazole-2-carbaldehyde / 5g / 552531270 / A110938 / / 10111-08-7 / MFCD00003544 / 96.089 / C4H4N2O
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eMolecules Ambeed / 5-Acetyl-2-methylpyridine / 250mg / 525027122 / A125783 / / 36357-38-7 / MFCD00128113 / 135.166 / C8H9NO
Ambeed / 5-Acetyl-2-methylpyridine / 250mg / 525027122 / A125783 / / 36357-38-7 / MFCD00128113 / 135.166 / C8H9NO
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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