Acetylides
Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | 348.39 g·mol⁻1 | C16H28O8 | 100 MG
Propargyl-PEG6-acid is a PEG-based linker bearing a terminal propargyl (alkyne) group, used as a click-chemistry reagent and as a linker in the synthesis of PROTACs and antibody-drug conjugates. The PEG6 spacer increases hydrophilicity and enables conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Contains a terminal propargyl (alkyne) functional group.
- Suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Used in synthesis of PROTACs and antibody-drug conjugates.
- PEG6 spacer provides hydrophilicity and improved solubility.
- Storage recommendations: pure form refrigerated or frozen for long-term stability; store solutions frozen.
Medchemexpress LLC E -Pent-2-enal 100g
(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners
Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | ≥97.0% | 348.39 g/mol | C16H28O8 | 250 MG
Propargyl-PEG6-acid is a PEG-based linker and click chemistry reagent containing a terminal alkyne. It is used as a linker in PROTAC and ADC synthesis and for copper-catalyzed azide-alkyne cycloaddition (CuAAc) bioconjugation reactions.
- cleavable PEG6 linker suitable for PROTAC and ADC synthesis
- contains a terminal propargyl (alkyne) group for click chemistry
- high purity (≥97.0% by NMR) suitable for research applications
- molecular weight 348.39 g/mol, molecular formula C16H28O8
- storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC Propargyl-PEG2-amine | 944561-44-8 | 99.6% | 143.18 g/mol | C7H13NO2 | 5 G
Propargyl-PEG2-amine is a short polyethylene glycol (PEG2) linker with a terminal propargyl (alkyne) group and a primary amine, used to introduce alkyne handles for click chemistry and bioconjugation.
- Short PEG2 spacer with terminal alkyne and primary amine.
- Suitable for click chemistry (CuAAC) and other bioconjugation reactions.
- Molecular weight 143.18 g/mol; formula C7H13NO2.
- Offered as a 5 g powder; store at 4°C, protect from light, under nitrogen.
- CAS number 944561-44-8 for unambiguous identification.
eMolecules 881402-25-1 | 2-Fluoro-3-(trifluoromethoxy)benzeneboronic acid | Apollo Scientific | MFCD11045053 | 223.920 | C7H5BF4O3 | 95.000 | OB(O)c1cccc(OC(F)(F)F)c1F | 1g | 562441206
2-Fluoro-3-(trifluoromethoxy)benzeneboronic acid | Apollo Scientific | 881402-25-1 | MFCD11045053 | 223.920 | C7H5BF4O3 | 95.000 | OB(O)c1cccc(OC(F)(F)F)c1F | 1g | 562441206
Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 100 MG
Propargyl-PEG5-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) | 2112732-01-9 | 519.58 | 25 MG
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs and acts as a click chemistry reagent. This linker contains an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess azide groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 1 G
Propargyl-PEG5-Br is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs and functions as a click chemistry reagent. It contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Enables synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
- Supports development of PROTACs for target protein degradation
Medchemexpress LLC Propargyl-PEG2-NHS ester | 2512228-06-5 | ≥98.0% | 269.25 g/mol | 100 MG
This PEG-based linker is designed for the synthesis of proteolysis-targeting chimeras (PROTACs), which are molecules that utilize the ubiquitin-proteasome system to degrade target proteins. It functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.
- Functions as a linker in targeted protein degradation research.
- Acts as a click chemistry reagent.
- Contains an alkyne functional group for specific reactions.
- Can undergo copper-catalyzed azide-alkyne cycloaddition.
- Enables conjugation with azide-containing molecules.
- Offers high purity for reliable experimental results.
Medchemexpress LLC Bis-propargyl-PEG8 10mg | 1092554-87-4 | 10 MG
Bis-propargyl-PEG8 is a PEG8-based bifunctional linker bearing terminal propargyl (alkyne) groups, used as a click-chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) in PROTAC and bioconjugation synthesis.
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Suitable for PROTAC linker construction and bioconjugation chemistry.
- PEG8 spacer improves solubility and provides flexible linkage length.
- Contains two terminal alkynes for dual conjugation sites.
- Supplied in small, pre-weighed mg quantities for research applications.