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Medchemexpress LLC Propargyl-PEG3-bromide | 203740-63-0 | 97.7% | 251.12 | 1 G
Supplier: Medchemexpress LLC HY1400361G
Propargyl-PEG3-bromide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, containing an alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Click chemistry
- Alkynes
- PROTAC synthesis
- Disease areas: Cancer, Cancer targeted therapy
- PROTAC linkers
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