Acetylides
Medchemexpress LLC Propargyl-PEG3-CH2COOH | 1694731-93-5 | 98.0% | 25 MG
Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Propargyl-PEG5-amine | 1589522-46-2 | MFCD27977505 | 98.9% | 275.34 g/mol | C13H25NO5 | 250 MG
Propargyl-PEG5-amine is a PEG-based linker reagent used as an alkyne functional handle for click chemistry and as a non-cleavable linker in ADC and PROTAC synthesis.
- PEG-based alkyne linker for conjugation and click chemistry.
- Non-cleavable linker suitable for ADC and PROTAC applications.
- Provides an alkyne handle for copper-catalyzed azide-alkyne cycloaddition.
- High purity and fully characterized by LCMS, HNMR, and RP-HPLC.
- Available in multiple pack sizes, including 250 MG.
- Colorless to light yellow liquid with a density of 1.049 g/cm3.
eMolecules Combi-Blocks (Bicyclo[1 1 1]pent-1-yl)methanol 250mg 388722073 QJ-7542 98 000 22287-32-7 MFCD28040494 98 145 C6H10O
Combi-Blocks (Bicyclo[1 1 1]pent-1-yl)methanol 250mg 388722073 QJ-7542 98 000 22287-32-7 MFCD28040494 98 145 C6H10O
Medchemexpress LLC VQW-765 | 669770-29-0 | 99.6% | 294.39 | 25 MG
VQW-765 (AQW-051) is a selective and orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonist. It demonstrates anxiolytic-like effects in vivo and is suitable for research into anxiety disorders and acute performance anxiety.
- Selective and orally active α7-nAChR agonist.
- Demonstrates anxiolytic-like effects in vivo.
- Suitable for research on anxiety disorder and acute performance anxiety.
- Increases cognitive effect and learning/memory performance.
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 5 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 100 mL Glass (Septum)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 100.4 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Accela Chembio Inc MF: C7H5N | MW: 103.12 | >97% | Flash Point: 76 celsius | BP: 90¿C/30mmHg | Density: 1.0190.
MF: C7H5N | MW: 103.12 | >97% | Flash Point: 76 celsius | BP: 90¿C/30mmHg | Density: 1.0190.
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 200 mg | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 200 mg. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 200 mg
- Net Weight: 0.2 g
- Gross Weight: 6.9 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 25 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
eMolecules Chem-Impex Trimethylsilylacetylene 1kg 112760621 24539 0 000 1066-54-2 MFCD00008569 98 220 C5H10Si
Chem-Impex Trimethylsilylacetylene 1kg 112760621 24539 0 000 1066-54-2 MFCD00008569 98 220 C5H10Si
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 1 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 30 mL Glass (28-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 50.1 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 10 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
eMolecules Ambeed / 1-Phenyl-1-hexyne / 250mg / 517263003 / A929993 / / 1129-65-3 / MFCD00039969 / 158.244 / C12H14
Ambeed / 1-Phenyl-1-hexyne / 250mg / 517263003 / A929993 / / 1129-65-3 / MFCD00039969 / 158.244 / C12H14
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 100 MG
Propargyl-PEG9-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess Azide groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules possessing azide groups