Acetylides
Accela Chembio Inc MF: C7H5N | MW: 103.12 | >97% | Flash Point: 76 celsius | BP: 90¿C/30mmHg | Density: 1.0190.
MF: C7H5N | MW: 103.12 | >97% | Flash Point: 76 celsius | BP: 90¿C/30mmHg | Density: 1.0190.
Medchemexpress LLC Propargyl-PEG12-OH 50mg | 1036204-61-1 | 584.69 | C27H52O13 | 50 MG
Propargyl-PEG12-OH is a PEG12-based linker bearing a terminal propargyl (alkyne) group and a hydroxyl terminus, intended for use as a click-chemistry-compatible spacer in PROTAC synthesis and bioconjugation. It has a molecular weight of 584.69 and CAS 1036204-61-1, and is supplied as a small laboratory vial.
- Terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- PEG12 spacer increases flexibility and aqueous solubility.
- Hydroxyl terminus enables further functionalization or conjugation.
- Analytical purity ≥98.0% (NMR) suitable for synthetic applications.
- Recommended storage: pure form -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Propargyl-PEG4-Boc | 1355197-66-8 | 316.39 | 250 MG
Propargyl-PEG4-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that readily undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This reagent facilitates the creation of PROTACs, which are compounds that exploit the ubiquitin-proteasome system to degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
- Used in the synthesis of PROTACs
Chem-Impex International, Inc. 3-Ethynylaniline | MFCD00014779 | 5G
3-Ethynylaniline, MFCD00014779, 5G
Medchemexpress LLC Propargyl-PEG3-bromide | 203740-63-0 | 97.7% | 251.12 | 1 G
Propargyl-PEG3-bromide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, containing an alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Click chemistry
- Alkynes
- PROTAC synthesis
- Disease areas: Cancer, Cancer targeted therapy
- PROTAC linkers
Medchemexpress LLC N-(Propargyl-PEG4)-biocytin | 2055042-71-0 | 98.0% | C28H46N4O9S | 250 MG
N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other the protein of interest, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports targeted protein degradation
Aobchem 4-Phenyl-3-butyn-2-ol | ≥97% | CAS 5876-76-6 | C10H10O | 10g
4-Phenyl-3-butyn-2-ol | ≥97% | CAS 5876-76-6 | C10H10O | 10g
Aobchem 4-Phenyl-3-butyn-2-ol | ≥97% | CAS 5876-76-6 | C10H10O | 5g
4-Phenyl-3-butyn-2-ol | ≥97% | CAS 5876-76-6 | C10H10O | 5g
Aobchem 1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 500mg
1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 500mg
Aobchem 1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 1g
1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 1g
Aobchem 3-Butyn-1-ol 1-methanesulfonate | ≥95% | CAS 72486-09-0 | C5H8O3S | 10g
3-Butyn-1-ol 1-methanesulfonate | ≥95% | CAS 72486-09-0 | C5H8O3S | 10g
Medchemexpress LLC Propargyl-PEG1-NHS ester | 1174157-65-3 | 99.7% | 225.20 g/mol | C10H11NO5 | 250 MG
A non-cleavable one-unit polyethylene glycol (PEG) linker supplied as an NHS ester with a terminal propargyl (alkyne) group. Designed for click chemistry (CuAAC) and antibody-agent conjugation, it is provided as a colorless to light-yellow solid-liquid mixture with high purity and recommended cold storage.
- One-unit PEG linker for minimal spacer length.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- NHS ester allows efficient coupling to primary amines.
- High purity suitable for conjugation chemistry.
- Cold storage recommended for long-term stability.
Medchemexpress LLC Fmoc-amino-PEG3-CH2COOH | 139338-72-0 | 99.8% | 429.46 | 1 G
Fmoc-amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
Aobchem 3-Butyn-1-ol | ≥95% | CAS 927-74-2 | C4H6O | 100g
3-Butyn-1-ol | ≥95% | CAS 927-74-2 | C4H6O | 100g