Halohydrins
Apexbio Technology LLC YH239-EE 1364488-67-4 50mg
YH239-EE (CAS 1364488-67-4) is a small molecule antagonist of the p53-MDM2 interaction By disrupting the binding between p53 a tumor suppressor transcription factor and its negative regulator MDM2 YH239-EE reactivates p53 signaling pathways In acute myeloid leukemia (AML) cell models such as OCI-AML-3 MOLM-13 and NB4 YH239-EE inhibits cell proliferation and induces cell cycle arrest accompanied by significant accumulation of sub-G1 populations It promotes apoptosis with rates observed up to 13 1-fold over control in NB4 cells and activates caspase 3/7 in MOLM-13 cells Enantiomers display distinct biological activity with EC50 values of 7 5 M and 25 2 M YH239-EE serves as a valuable tool for studying p53-MDM2 modulation in cancer research
Cambridge Isotope Laboratories Mono-Deca Predominant PCB Calibration Solutions (CS1-CS5) 5 x 0 2 mL
Mono-Deca Predominant PCB Calibration Solutions (CS1-CS5) 5 x 0 2 mL
Medchemexpress LLC Proteasome 20S C2/HC2 antibody (YA2301) | 50 UL
Proteasome 20S C2/HC2 Antibody (YA2301) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Proteasome 20S C2/HC2. It is for research use only and not intended for sale to patients. This antibody is a component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It plays numerous essential roles within the cell by associating with different regulatory particles, participating in ATP-dependent degradation of ubiquitinated proteins and ubiquitin-independent protein degradation.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets Proteasome 20S C2/HC2
- For research use only
- Involved in proteolytic degradation of most intracellular proteins
- Essential for maintaining protein homeostasis
- Mediates both ATP-dependent and ubiquitin-independent protein degradation
Medchemexpress LLC 1-Tetradecanol | 112-72-1 | 214.39 | 50 G
1-Tetradecanol is a straight-chain saturated fatty alcohol that also acts as an antibacterial agent. It can be isolated from Myristica fragrans and has shown both antibacterial and anti-inflammatory activity, particularly in relation to periodontitis.
- Straight-chain saturated fatty alcohol
- Antibacterial agent
- Anti-inflammatory activity (periodontitis)
- Reduces IL-8 production in AGS cells in response to H. pylori
- Reduces melanin in B16F10 cells without cytotoxicity
Cambridge Isotope Laboratories Sodium tetrafluoro-2-(heptafluoropropoxy)propanoate (HFPO-DA) GenX (unlabeled) 100 ug/mL in methanol 1 2 mL
Sodium tetrafluoro-2-(heptafluoropropoxy)propanoate (HFPO-DA) GenX (unlabeled) 100 ug/mL in methanol 1 2 mL
Sigma Aldrich Fine Chemicals Biosciences 2-Ethoxyethanol ReagentPlu1L
2-Ethoxyethanol is a glycol ether. It has been reported as a precursor for ethoxyacetic acid (EAA). Various physical properties (density refractive index viscosity and speed of sound) of its binary mixtures with n-alkanes 2 2 4-trimethylpentane and cyclohexane have been evaluated. High-pressure vapor-liquid equilibrium (VLE) data of its binary mixtures with CO2 have been reported. It can be used as a solvent in the spectrophotometric determination of iron(III) by using the ligand N N-bis(2-hydroxy-5-bromo-benzyl)1 2 diaminopropane (HBDAP).
eMolecules 1,2-Dibromo-1-chloro-1,2,2-trifluoroethane | 354-51-8 | MFCD00039316 | 1g
Combi-Blocks | 1,2-Dibromo-1-chloro-1,2,2-trifluoroethane | 1g | 335350832 | QC-4166 | 95.000 | 354-51-8 | MFCD00039316 | 276.280 | C2Br2ClF3
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Medchemexpress LLC Ginsenoside F3 | 62025-50-7 | 770.99 | 1 ML
Ginsenoside F3, a component of PPTGs (a minor saponin in the leaves of Panax ginseng), has immunoenhancing activity by regulating the production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10).
- Purity: 99.84%.
Medchemexpress LLC C2/Complement C2 Hu 5ug
C2/Complement C2 protein is essential in the classical pathway of the complement system Activated by factor C1 C2 is cleaved into C2b and C2a As a serine protease C2a interacts with C4b generating the C3 or C5 convertase This crucial process activates and amplifies the complement cascade C2/Complement C2 Protein Human (HEK293 His) is the recombinant human-derived C2/Complement C2 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC C2/Complement C2 Hu 100ug
C2/Complement C2 protein is essential in the classical pathway of the complement system Activated by factor C1 C2 is cleaved into C2b and C2a As a serine protease C2a interacts with C4b generating the C3 or C5 convertase This crucial process activates and amplifies the complement cascade C2/Complement C2 Protein Human (HEK293 His) is the recombinant human-derived C2/Complement C2 protein expressed by HEK293 with C-His labeled tag
Cell Signaling Technology F3/Contactin (D7D4X) Rabbit mAb 20 ul
F3/Contactin (D7D4X) Rabbit mAb 20 ul