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BAY-6035 is a chemical probe and a potent, selective, and substrate-competitive inhibitor of SMYD3. It inhibits the methylation of MEKK2 peptide with an IC50 of 88 nM.
Potent, selective, and substrate-competitive inhibitor of SMYD3.
Inhibits methylation of MEKK2 peptide with an IC50 of 88 nM.
Exhibits more than 100-fold selectivity over other histone methyltransferases.
Inhibits the methylation of MEKK2 in cells with an IC50 of 70 nM.
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