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Pifithrin-β hydrobromide is a small-molecule inhibitor of the p53 pathway supplied as the hydrobromide salt. It reversibly blocks p53 transcriptional activity (reported IC50 = 23 μM) and is used as a research tool in cellular and biochemical studies of apoptosis and ferroptosis. Chemical formula C16H17BrN2S; molecular weight 349.29 g/mol; CAS 511296-88-1.
Reversible p53 inhibitor with reported IC50 of 23 μM.
Hydrobromide salt for improved solubility and handling.
Reported high purity (≥98% by HPLC) in supplier listings.
Suitable for cellular and biochemical assays studying apoptosis and ferroptosis.
Store sealed at 4 °C as a solid; in solution store at -80 °C for long-term stability.
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