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Homatropine Methylbromide (CAS 80-49-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It inhibits muscarinic signaling by blocking receptor activity on endothelial and smooth muscle cells as demonstrated in WKY-E and SHR-E models with IC50 values of 162 5 nM and 170 3 nM respectively This compound is utilized in studies investigating cholinergic modulation of vascular tone and smooth muscle function offering a tool for dissecting the roles of muscarinic receptors in cardiovascular and autonomic research contexts
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