Hydrochlorides
Medchemexpress LLC PXS-4787 hydrochloride | 2409964-40-3 | C10H13ClFNO2S | 10 MM * 1 ML
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor that abolishes lysyl oxidase activity. It inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). This compound also reduces the deposition and crosslinking of collagen I secreted by human fibroblasts. It is for research use only and not sold to patients.
- Specific and effective pan-LOX inhibitor
- Abolishes lysyl oxidase activity
- Inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4)
- Reduces deposition and crosslinking of collagen I secreted by human fibroblasts
- For research use only
Medchemexpress LLC OPC-14523 hydrochlor 10mM 1mL | 145969-31-9 | 450.40 g/mol | C23H29Cl2N3O2 | 1 ML
OPC-14523 hydrochloride is a sigma and 5-HT1A receptor agonist supplied as a hydrochloride salt for research use. It is available as a lyophilized solid and as a ready-to-use 10 mM solution in DMSO, with documented solubility and storage recommendations for in vitro and in vivo studies.
- Hydrochloride salt form for improved stability and handling.
- High purity (99.95%) suitable for pharmacology studies.
- Chemical formula C23H29Cl2N3O2; molecular weight 450.40 g/mol.
- Available as solid in multiple mg sizes and as a 10 mM, 1 mL solution in DMSO.
- Soluble in DMSO (~83.3 mg/mL) and moderately soluble in water with warming.
- Recommended storage: sealed, away from moisture; in solvent: -20°C short term, -80°C long term.
![Medchemexpress LLC 3(2H)-pyridazinone, 4,5-dihydro-6-[4-(4-pyridinylamino)phenyl]-, hydrochloride | 98326-33-1 | 99.8% | 302.76 g/mol | C15H15ClN4O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247664.png-250.jpg)
Medchemexpress LLC 3(2H)-pyridazinone, 4,5-dihydro-6-[4-(4-pyridinylamino)phenyl]-, hydrochloride | 98326-33-1 | 99.8% | 302.76 g/mol | C15H15ClN4O | 1 ML
Senazodan hydrochloride is the monohydrochloride salt of Senazodan (MCI 154), a Ca2+ sensitiser that also exhibits inhibitory activity against phosphodiesterase III (PDE III). It is provided for research use in biochemical and pharmacological studies and is supplied in solid and solution formats for assay applications.
- High purity (99.84%) as verified by certificate of analysis.
- Exact chemical identity: C15H15ClN4O, MW 302.76 g/mol, CAS 98326-33-1.
- Suitable for biochemical and pharmacological assays involving Ca2+ sensitization and PDE III modulation.
- Available as solid powder and as concentrated solution formats for convenient dosing.
- COA available for batch-specific quality and analytical data.
eMolecules 115445-31-3 | 3-(Trifluoroacetamido)pyrrolidine hydrochloride | Oakwood Chemical | MFCD01090944 | 218.600 | C6H10ClF3N2O | 98.000 | Cl.FC(F)(F)C(=O)NC1CCNC1 | 1g | 537671980
3-(Trifluoroacetamido)pyrrolidine hydrochloride | Oakwood Chemical | 115445-31-3 | MFCD01090944 | 218.600 | C6H10ClF3N2O | 98.000 | Cl.FC(F)(F)C(=O)NC1CCNC1 | 1g | 537671980
Medchemexpress LLC Vu 0238429 | 1160247-92-6 | 99.9% | 1 ML
Vu 0238429 is a positive allosteric modulator of the muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5) with an EC50 of 1.16 μM. It is supplied as a 10 mM solution in DMSO or as a solid and is intended for research use.
- Positive allosteric modulation of M5 receptor (EC50 1.16 μM).
- Greater than 30-fold selectivity over M1 and M3 receptors.
- No potentiator activity observed at M2 or M4 receptors.
- Available as 10 mM solution in DMSO and multiple solid sizes.
- High reported purity (≈99.9%).
Medchemexpress LLC Tyramine hydrochloride | 60-19-5 | MFCD00012901 | 99.8% | 173.64 | C8H12ClNO | 1 G
Tyramine hydrochloride is the hydrochloride salt of the endogenous monoamine tyramine, supplied as a solid reference standard for biochemical and neuroscience research. It is used in studies of monoamine metabolism and neuromodulation, and as an analytical standard for chromatography and mass spectrometry.
- High purity (99.82%) suitable for analytical and research applications.
- White to light yellow solid, stable for storage and handling.
- Chemical formula C8H12ClNO and molecular weight 173.64 g/mol.
- Intended for use in neuroscience and neuromodulation studies.
- Available in multiple package sizes to support small-scale experiments.
Medchemexpress LLC Tirofiban hydrochloride monohydrate | 150915-40-5 | 99.9% | 495.07 | 500 MG
Tirofiban hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist. It inhibits fibrinogen binding to this receptor and demonstrates antithrombotic activity. This compound also induces proliferation and migration on endothelial cells by stimulating VEGF production, and can significantly reduce myocardial no-reflow and ischemia-reperfusion injury by improving myocardial microvascular structural and endothelial dysfunction in ischemic areas.
- Selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist
- Inhibits fibrinogen binding
- Antithrombotic activity
- Induces proliferation and migration on endothelial cells
- Stimulates VEGF production
- Reduces myocardial no-reflow and ischemia-reperfusion injury
- Alleviates myocardial microvascular dysfunction
Apexbio Technology LLC RS 127445 HCl 199864-87-4 10mg
RS 127445 HCl (CAS 199864-87-4) is a small-molecule antagonist targeting the serotonin 5-HT2B receptor a member of the G-protein coupled receptor family It is designed to selectively block 5-HT2B receptor activity thereby modulating intracellular signaling pathways such as calcium elevation and inositol phosphate production RS 127445 HCl exerts its biological activity primarily through selective antagonism of the 5-HT2B receptor In isolated tissue preparations such as rat stomach fundus and jugular vein RS 127445 HCl inhibits serotonin-induced contraction Based on these pharmacological properties RS 127445 HCl holds research potential in studies of 5-HT2B receptor function and related physiological processes
Medchemexpress LLC MLN120B dihydrochloride | 1782573-78-7 | C19H17Cl3N4O2 | 25 MG
MLN120B dihydrochloride is a potent, ATP competitive, and orally active inhibitor of IKKβ with an IC50 of 60 nM. This compound has demonstrated effectiveness in inhibiting multiple myeloma cell growth both in vitro and in vivo, and is also applicable for research related to rheumatoid arthritis.
- Potent, ATP competitive, and orally active IKKβ inhibitor
- Inhibits multiple myeloma cell growth in vitro and in vivo
- Can be used for research of rheumatoid arthritis
eMolecules 121010-86-4 | (R)-3-Aminopyrrolidin-2-one | MFCD11501145 | 1g
Ambeed | 3-Bromo-2-hydroxybenzonitrile | 1g | 552745984 | A597142 | 13073-28-4 | MFCD11042854 | 198.019 | C7H4BrNO
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Medchemexpress LLC Erlotinib hydrochloride | 183319-69-9 | >99.0% | 10 G
Erlotinib hydrochloride is the hydrochloride salt of erlotinib, a potent epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor used as a research reagent. It inhibits purified EGFR kinase (IC50 ≈ 2 nM) and shows anti-tumor activity in preclinical studies. For research use only.
- Inhibits EGFR kinase (IC50 ≈ 2 nM).
- Molecular weight 429.90 g/mol.
- Chemical formula C22H24ClN3O4.
- Purity >99% (manufacturer claim).
- Supplied as an off-white powder; store at -20°C.
Medchemexpress LLC Zk756326 dihydrochloride | 1780259-94-0 | MFCD09038571 | 99.9% | 429.38 | C21H30Cl2N2O3 | 1 ML
ZK756326 dihydrochloride is a small-molecule, nonpeptide agonist of the CC chemokine receptor CCR8 supplied for research use in biochemical and cell-based assays. It is available as a 10 mM solution in DMSO (1 mL) and as crystalline solids, and is provided with analytical documentation to verify identity and purity.
- Nonpeptide CCR8 agonist suitable for receptor pharmacology studies.
- Offered as 10 mM solution in DMSO (1 mL) and in multiple solid quantities for assay flexibility.
- High purity (99.87%) supporting reproducible experimental results.
- Comes with analytical documentation: COA, HNMR, LCMS, and SDS.
- Storage guidance for stability: sealed storage; in solvent, -80°C (6 months) or -20°C (1 month).
eMolecules 39254-63-2 | Acetimidohydrazide hydrochloride | MFCD01746339 | 1g
ChemScene | 5-Chloro-5-deoxyadenosine | 1g | 536840491 | CS-W000275 | 892-48-8 | 285.690 | C10H12ClN5O3
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Medchemexpress LLC SB-203186 hydrochloride | 207572-69-8 | MFCD04037547 | 99.9% | 308.80 g/mol | C16H21ClN2O2 | 1 ML
SB-203186 hydrochloride is a potent, selective, competitive antagonist of the 5-HT4 serotonin receptor used in pharmacology research to probe receptor-mediated responses in tissue and cell-based assays. It is provided as a solid or as a pre-made solution for convenient in vitro use.
- Potent, selective 5-HT4 receptor antagonist.
- High purity (99.9%).
- Molecular weight 308.80 g/mol.
- Supplied as a 10 mM solution in DMSO (1 mL) or as solids in multiple sizes.
- Soluble in DMSO up to 100 mg/mL; may require ultrasonic treatment.
- Store sealed, away from moisture and light; in solvent store at -80°C for long-term stability.
Medchemexpress LLC SB-224289 (hydrochloride) | 180084-26-8 | MFCD03788209 | 99.0% | 557.08 | C32H33ClN4O3 | 50 MG
SB-224289 hydrochloride is a research-grade hydrochloride salt that acts as a selective 5-HT1B (serotonin 1B) receptor antagonist, used in preclinical studies to probe serotonergic signaling and related behavioral effects such as anxiolysis. The compound is supplied with high stated purity and should be stored under low-temperature, moisture-free conditions.
- Selective 5-HT1B receptor antagonist for targeted pharmacological studies.
- Useful for probing serotonergic signaling and anxiolytic-related behavior in preclinical research.
- High stated purity (99.0%).
- Supplied as the hydrochloride salt in solid form for stability.
- Recommended storage at low temperature, protected from moisture.
- Available in small research quantities suitable for laboratory experiments.