Hydrochlorides
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![Medchemexpress LLC 7h-Indeno[2,1-c]quinolin-7-one, 6-[[2-(dimethylamino)ethyl)amino]-3-hydroxy-, hydrochloride (1:2) | 174634-09-4 | 98.5% | 406.31 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 7h-Indeno[2,1-c]quinolin-7-one, 6-[[2-(dimethylamino)ethyl)amino]-3-hydroxy-, hydrochloride (1:2) | 174634-09-4 | 98.5% | 406.31 | 25 MG
TAS-103 dihydrochloride is a dual inhibitor of DNA topoisomerase I/II. It is used for cancer research and is intended for research use only.
- Dual inhibitor of DNA topoisomerase I/II
- Utilized in cancer research
- Active on CCRF-CEM cells with an IC50 of 5 nM
- Highly cytotoxic to Lewis lung carcinoma (LLC) cells
- Inhibits viability of HeLa cells with an IC50 of 40 nM
- Causes significant tumor growth suppression in mice bearing Lewis lung carcinoma (LLC) cells
