Hexadimethrine bromide, also known as Polybrene, is a cationic polymer commonly used to enhance the efficiency of retrovirus vector-mediated gene transfer. It is intended for research use only.
- Enhances retrovirus vector-mediated gene transfer
- Considered non-toxic at low concentrations
- Can affect cell proliferation at concentrations greater than 10 μg/mL in some cell types
- Causes trypsinized cells exposed to it to appear visibly larger