Organic oxoazanium compounds
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Medchemexpress LLC L-364,373 | 103342-82-1 | 99.7% | 397.44 g·mol⁻¹ | C25H20FN3O | 5 MG
L-364,373 (R-L3) is a small-molecule activator of voltage-gated Kv7.1 (KCNQ1)/mink potassium channels. It enhances the slow delayed rectifier potassium current (Iks), shortens action potential duration in cardiac myocytes, and suppresses early afterdepolarizations, making it useful for electrophysiology and cardiovascular research.
- CAS number: 103342-82-1.
- Purity: 99.67%.
- Molecular weight: 397.44 g·mol⁻¹.
- Chemical formula: C25H20FN3O.
- Appearance: white to off-white solid.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
- Solubility: DMSO 100 mg/mL; in vivo formulations documented for dosing.
- Pack size: 5 mg available.
