Organic tin salts
Sigma Aldrich Dibutyltin Dichloride
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Medchemexpress LLC CD40L/CD154/TRAP trimer protein, human (HEK293, His-Flag) | >= 95% | 55 kDa | 100 UG
CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, specifically expressed on activated CD4+ T-lymphocytes, involved in the activation of the NF-κB/MAPK pathway, B cell differentiation, maturation, and apoptosis. This human CD40L/CD154/TRAP Trimer Protein is expressed in HEK293 cells with N-terminal His- and Flag-tags.
- Functions as a ligand for CD40/TNFRSF5
- Involved in NF-κB/MAPK pathway activation
- Participates in B cell differentiation, maturation, and apoptosis
- Expressed in HEK293 cells with N-terminal His- and Flag-tags
- Approximately 55 kDa molecular weight
- Purity of >= 95%
Medchemexpress LLC CD40L/CD154/TRAP Trimer Protein, Human (HEK293, His-Flag) | ≥ 95% | Approximately 55 kDa | 50 UG
CD40L/CD154/TRAP Trimer Protein is a recombinant human protein expressed in HEK293 cells with N-terminal His- and Flag-tags. It is the soluble form of CD40L, crucial for immune responses, including T-cell and B-cell activation, differentiation, and survival, and interacts with integrins. This protein has an approximate molecular weight of 55 kDa and a purity of ≥ 95%.
- High purity: ≥ 95% as determined by Bis-Tris PAGE
- Expressed in HEK293 cells for proper folding and post-translational modifications
- Tagged for detection and purification
- Biologically active: acts as a ligand for CD40/TNFRSF5
- Suitable for immunology and cell biology research applications
Medchemexpress LLC CD40L/CD154/TRAP Trimer Protein, Human (HEK293, His-Flag) | ≥ 95% | Predicted: 52.4 kDa, Apparent: ~55 kDa | 20 UG
CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5 that generates a costimulatory signal up-regulating IL-4 synthesis. It is specifically expressed on activated CD4+ T-lymphocytes and involved in NF-κB/MAPK pathway activation, B cell differentiation, maturation, and apoptosis. This full-length monomer (M113-L261) is expressed in HEK293 cells with N-terminal His- and Flag-tag, belonging to the tumor necrosis factor (TNF) family. It plays a major role in immune response and is a target for inflammation, binding and signaling through integrins.
- Ligand to CD40/TNFRSF5, generating costimulatory signals
- Expressed on activated CD4+ T-lymphocytes
- Involved in NF-κB/MAPK pathway activation and B cell processes
- Enhances cytokine production like IL-4, IL-10, interferon-γ, and TNF-α
- Induces endothelial cell VCAM-1 expression in vitro and in vivo