Organofluorides
Sigma Organic Chemistry 3 3 3-Trifluoropropioni | 5ml | 2516-99-6 | MFCD00153292
3 3 3-Trifluoropropioni , 5ml
About this item:
CAS #: 2516-99-6
MDL #: MFCD00153292
Purity: ≥98
Molecular Weight: 128.05
UNSPSC Code: 12352100
Sigma Organic Chemistry Heptafluoro-2-iodopropane | 25G | 677-69-0 | MFCD00042089
CAS #: 677-69-0
MDL #: MFCD00042089
Purity: >98 %
UNSPSC Code: 12352100
Molecular Weight: 295.93
Sigma Organic Chemistry 3,5-Bis(trifluoromethyl)benzaldehyde | 5G | 401-95-6 | MFCD00010206
CAS #: 401-95-6
MDL #: MFCD00010206
Purity: >97 %
UNSPSC Code: 12352100
Molecular Weight: 242.12
Sigma Organic Chemistry Perfluoro-1-butanesulfonyl fluoride | 25G | 375-72-4 | MFCD00007422
CAS #: 375-72-4
MDL #: MFCD00007422
Purity: >96 %
UNSPSC Code: 12352100
Molecular Weight: 302.09
Sigma Organic Chemistry Perfluoro-1-butanesulfonyl fluoride | 100G | 375-72-4 | MFCD00007422
CAS #: 375-72-4
MDL #: MFCD00007422
Purity: >96 %
UNSPSC Code: 12352100
Molecular Weight: 302.09
Sigma Organic Chemistry alpha-(Trifluoromethyl)benzyl alcohol | 5G | 340-05-6 | MFCD00004498
CAS #: 340-05-6
MDL #: MFCD00004498
Purity: >98 %
UNSPSC Code: 12352100
Molecular Weight: 176.14
Sigma Organic Chemistry 2,6,6-Trimethyl-2-cyclohexene-1,4-dione | 25G | 1125-21-9 | MFCD00043119
CAS #: 1125-21-9
MDL #: MFCD00043119
Purity: >98 %
UNSPSC Code: 12352100
Molecular Weight: 152.19
Apexbio Technology LLC PYR-41 418805-02-4 10mM (in 1mL DMSO)
PYR-41 (CAS 418805-02-4) is a selective inhibitor of ubiquitin-activating enzyme (E1) involved in the ubiquitination cascade essential for diverse cellular processes such as protein degradation apoptosis DNA repair and signaling pathways By inhibiting E1 activity PYR-41 impedes ubiquitination reactions resulting in decreased proteasomal degradation In vitro studies demonstrate that PYR-41 also increases overall cellular SUMOylation and attenuates cytokine-induced NF- B activation through interference with TRAF6-dependent (non-proteasomal) ubiquitination and stabilization of I B Currently PYR-41 remains in preclinical research serving primarily as an investigative tool to explore ubiquitination mechanisms and related signal transduction pathways
Apexbio Technology LLC Cyclo (-RGDfK) 161552-03-0 100mg
Cyclo(-RGDfK) is a cyclic pentapeptide that functions as an inhibitor targeting the integrin v 3 Integrins are transmembrane receptors mediating cell adhesion by recognizing specific peptide sequences notably the Arg-Gly-Asp (RGD) motif Integrin v 3 is involved in cell adhesion processes such as angiogenesis tissue remodeling and tumor development and is abundantly expressed on activated endothelial cells and various tumor cells Cyclo(-RGDfK) specifically binds integrin v 3 disrupting integrin-mediated cell attachment Consequently it is frequently utilized in bioengineering applications to modify biomaterial surfaces for enhanced cellular adherence and integration Additionally cyclo(-RGDfK) serves as a targeting ligand in imaging probes aimed at localizing integrin-positive tissues in cancer research
Apexbio Technology LLC Verdinexor (KPT-335) 1392136-43-4 10mM (in 1mL DMSO)
Verdinexor (KPT-335 CAS 1392136-43-4) is a selective inhibitor of nuclear export (SINE) targeting exportin-1 (XPO1) a protein that mediates nuclear export of various cargos critical in cell proliferation and cycle regulation Verdinexor treatment in influenza A- or B-infected A549 cells leads to nuclear accumulation of viral ribonucleoproteins (vRNP) and altered localization of viral NS1 protein effectively blocking nuclear export and viral replication In mouse models infected with influenza A virus verdinexor significantly reduces pulmonary viral titers and inflammatory cytokine expression Additionally verdinexor exhibits cytotoxic activity against canine lymphoma cells Therefore verdinexor serves as a valuable tool compound in antiviral and oncology research
Sigma Organic Chemistry [2-(Methacryloyloxy)ethyl]trimethylammonium chloride solution | 250ML | 5039-78-1 | MFCD00060097
[2-(Methacryloyloxy)ethyl]trimethylammonium chloride solution, 250ML
About This Item:
Density: 1.105 g/mL at 25 C
Refractive Index: n20/D 1.469
Storage: room temp
Sigma Organic Chemistry Poly(diallyldimethylammonium chloride) solution | 25ML | 26062-79-3 | MFCD00192409
Poly(diallyldimethylammonium chloride) solution, 25ML
About This Item:
Density: 1.04 g/mL at 25 C
Refractive Index: n20/D 1.37
Storage: room temp
Sigma Organic Chemistry Poly(diallyldimethylammonium chloride) solution | 25ML | 26062-79-3 | MFCD00192409
Poly(diallyldimethylammonium chloride) solution, 25ML
About This Item:
Density: 1.04 g/mL at 25 C
Refractive Index: n20/D 1.375
Storage: room temp
Sigma Organic Chemistry Trimethylolpropane ethoxylate triacrylate | 250ML | 28961-43-5
Trimethylolpropane ethoxylate triacrylate, 250ML
About This Item:
UNSPSC Code: 12162002
Density: 1.12 g/mL at 25 C
Refractive Index: n20/D 1.471 (lit.)
Storage: room temp
Selleck Chemical LLC PYR-41
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1 with no activity at E2 PYR-41 induce apoptosis