Organofluorides

Medchemexpress LLC 4-[4-[(2-thiiranylmethyl)sulfonyl]phenoxy]-benzenemethanamine monohydrochloride | 1807453-83-3 | MFCD34469331 | 97.2% | 371.90 | C16H18ClNO3S2 | 1MG

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ND-336 is a small-molecule selective inhibitor of matrix metalloproteinases MMP-2, MMP-9, and MMP-14 used in biochemical and in vivo research; it exhibits low-nanomolar to sub-micromolar potency and has been reported to accelerate diabetic wound healing in mice by reducing inflammation and promoting angiogenesis and re-epithelialization. The compound is supplied as a white to off-white solid, with high purity and recommended cold storage for long-term stability.

• Selective inhibitor of MMP-2, MMP-9, and MMP-14.
• Potency: Ki = 85 nM (MMP-2), 150 nM (MMP-9), 120 nM (MMP-14).
• Shown to accelerate wound healing in diabetic mouse models.
• High purity (97.2%) and white to off-white solid appearance.
• Soluble in DMSO at 30 mg/mL (requires ultrasonic and warming).
• Storage: solid at -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
• Suitable for biochemical assays and topical in vivo studies.