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Sulfonyl halides

Organic compounds that contain a carbon bonded to a sulfonyl functional group (a sulfur atom bonded with two oxygen atoms via double bonds) that is bonded to a halogen atom; halogen atoms include bromine, chlorine, fluorine, and iodine.

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1

Medchemexpress LLC Methacholine chloride | 62-51-1 | ≥98.0% | C8H18ClNO2 | 1 ML
SDP

Methacholine chloride is a potent muscarinic-3 (M3) agonist that acts directly on acetylcholine receptors on smooth muscle, leading to bronchoconstriction and narrowing of the airways. It is highly sensitive in identifying bronchial hyperresponsiveness (BHR) and serves as a diagnostic aid for assessing airway hyperresponsiveness (AHR) in individuals with asthma-like symptoms and normal resting expiratory flow rates.

  • Potent muscarinic-3 (M3) agonist
  • Acts on acetylcholine receptors on smooth muscle
  • Causes bronchoconstriction and airway narrowing
  • Identifies bronchial hyperresponsiveness (BHR)
  • Diagnostic aid for airway hyperresponsiveness (AHR)

ENCOMPASS_PREFERRED
2

Medchemexpress LLC Datelliptium chloride | 105118-14-7 | 397.94 | 10 MG
SDP

Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, exhibiting anti-tumor activities. It demonstrates significant cytotoxic effects in vitro and potent inhibitory activities against various murine solid tumors in vivo.

  • Exhibits significant cytotoxic effects after 2 hours of treatment in suspension and primary cultures of rat hepatocytes.
  • Mobilizes glycogen in rat systems in vitro in a concentration-dependent manner.
  • Leads to a concentration-dependent decrease in gluconeogenesis from lactate in cells.
  • Shows selective cytotoxicity for solid tumors over leukemia L1210.
  • Potent inhibitory activities in vivo against a variety of murine solid tumors.

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Datelliptium chloride | 105118-14-7 | 397.94 | 50 MG
SDP

Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities.

  • DNA-intercalating agent
  • Derived from ellipticine
  • Exhibits anti-tumor activities
  • Shows significantly cytotoxic effects in suspension and primary cultures of rat hepatocytes (100 μM after 2 hr treatment)
  • Mobilizes glycogen in rat systems in vitro concentration-dependently
  • Leads to a concentration-dependent decrease in gluconeogenesis from lactate in cells
  • Datelliptium acetate (a related form) is selectively cytotoxic for solid tumors over leukemia L1210
  • Datelliptium acetate shows potent inhibitory activities in vivo against various murine solid tumors upon intravenous administration

ENCOMPASS_PREFERRED