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Organoaluminum compounds possess direct bonds between carbon and aluminum atoms. Predominantly electrophilic, these compounds typically act as Lewis acids in reactions and play a large role in the field of organometallic chemistry.
IDE 1 (CAS 1160927-48-9) is a small-molecule compound designed to promote differentiation of stem cells toward the definitive endoderm lineage by activating receptors involved in the TGF- signaling pathway IDE 1 exerts its biological activity primarily through activation of the TGF- signaling pathway In in vitro studies IDE 1 induces definitive endoderm specification from pluripotent stem cells Based on these pharmacological properties IDE 1 holds research potential in in vitro differentiation protocols to generate endoderm-derived cells such as hepatocytes and pancreatic cells and in studies investigating early embryonic lineage commitment and regenerative medicine
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IDE 1 (CAS 1160927-48-9) is a small-molecule compound designed to promote differentiation of stem cells toward the definitive endoderm lineage by activating receptors involved in the TGF- signaling pathway IDE 1 exerts its biological activity primarily through activation of the TGF- signaling pathway In in vitro studies IDE 1 induces definitive endoderm specification from pluripotent stem cells Based on these pharmacological properties IDE 1 holds research potential in in vitro differentiation protocols to generate endoderm-derived cells such as hepatocytes and pancreatic cells and in studies investigating early embryonic lineage commitment and regenerative medicine
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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Acetoacetic acid is an oxidative stress inducer. It affects the antioxidant enzyme system and lipoprotein metabolism by decreasing mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), and increasing malondialdehyde (MDA) content. It also inhibits very low-density lipoprotein (VLDL) assembly, leading to triglyceride (TG) accumulation in hepatocytes, making it useful for studying metabolic diseases.
Oxidative stress inducer
Impacts antioxidant enzyme system
Affects lipoprotein metabolism
Decreases SOD, CAT, and GSH-Px activity and mRNA expression
Increases malondialdehyde (MDA) content
Inhibits VLDL assembly
Leads to triglyceride (TG) accumulation in hepatocytes
Useful for studying metabolic diseases
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Also available in 5 mg, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Acetoacetic acid lithium salt (Lithium 3-Oxobutyrate) is a weak organic acid that can be produced in the human liver under certain conditions of poor Metabolism leading to excessive fatty acid breakdown (diabetes mellitus leading to diabetic ketoacidosis).
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Also available in 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Purity ≥98%
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