Organo-Metalloid Compounds

Organo-metalloid compounds possess direct bonds between carbon atoms and metalloid atoms. Organo-metalloid compounds are available in a range of chemical compositions, quantities, purities, and reagent grades.

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1,981 – 1,995 of 4,228 results

1,981

Medchemexpress LLC Azido-PEG3-C3-OH | 1807512-36-2 | 98.0% | C9H19N3O4 | 250 MG

Azido-PEG3-C3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This click chemistry reagent features an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Functions as a click chemistry reagent
Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions

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1,982

Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | >95.0% | C19H32N2O5 | 10MG

BCN-exo-PEG3-NH2 is a BCN-functionalized PEG3 amine linker used in bioorthogonal conjugation and PROTAC linker synthesis. It provides a strained alkyne handle and a terminal primary amine to enable modular coupling strategies, and is commonly supplied in research-scale quantities at high reported purity.

Provides a strained alkyne (BCN) for rapid bioorthogonal click reactions.
Contains a PEG3 spacer for flexibility and improved solubility.
Features a terminal primary amine for amide or reductive amination conjugation.
Suitable for linker construction in targeted degradation and bioconjugation workflows.
Supplied in research-scale quantities with supplier-reported high purity.

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1,983

Medchemexpress LLC 5,8,11-Trioxa-2,14-diazahexadecanoic acid, 16-bromo-15-oxo-, 1,1-dimethylethyl ester | 1421933-39-2 | ≥98.0% | C15H29BrN2O6 | 500 MG

Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by utilizing the ubiquitin-proteasome system, connecting ligands for an E3 ubiquitin ligase and the target protein via a linker.

Suitable for PROTAC synthesis
Utilizes PEG-based linker technology
Facilitates targeted protein degradation

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1,984

Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG

N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.

PEG-based PROTAC linker
Used in the synthesis of PROTACs
Applications in cancer-programmed cell death

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1,985

Medchemexpress LLC DPC-681 | 284661-68-3 | 99.7% | 669.85 | 10 MM * 1 ML

DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.

Potent and selective inhibitor of HIV protease.
Effective against wild-type HIV-1.
Shows no loss in potency toward recombinant mutant HIVs with the D30N mutation.
Exhibits a fivefold or smaller loss in potency toward mutant variants with three to five amino acid substitutions.
Hepatic extraction can be saturated in dogs, leading to increased bioavailability at higher doses.

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1,986

Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 250 MG

BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PEG-based PROTAC linker
Used in the synthesis of PROTACs
PROTACs contain two different ligands
One ligand for E3 ubiquitin ligase
Other ligand for target protein
Exploits intracellular ubiquitin-proteasome system
Selectively degrades target proteins

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1,987

Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 50 G

Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports.

PEG-based PROTAC linker
Can be used in the synthesis of PROTACs
Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports

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1,988

eMolecules 2243566-45-0 | m-PEG3-triethoxysilane | Broadpharm395.568 | C17H37NO7Si | 98.000 | CCO[Si](CCCNC(=O)CCOCCOCCOC)(OCC)OCC | 1g | 411413983

m-PEG3-triethoxysilane | Broadpharm | 2243566-45-0395.568 | C17H37NO7Si | 98.000 | CCO[Si](CCCNC(=O)CCOCCOCCOC)(OCC)OCC | 1g | 411413983

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1,989

TARGETMOL CHEMICALS INC SX-682 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SX-682 is a potent selective and orally bioavailable inhibitor of CXCR1/2 has the potential to treat castration-resistant prostate cancer. purity: 99%

Pricing & Availability

1,990

Medchemexpress LLC (S,R,S)-Ahpc-C6-Peg3-C4-Cl | 1835705-55-9 | MFCD31560478 | ≥95.0% | 751.42 g/mol | C38H59ClN4O7S | 500 MG

(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate used as a building block in targeted protein degradation (PROTAC) research. It supplies a halide-terminated PEG linker designed for coupling in degrader synthesis and related medicinal chemistry applications.

Used as a VHL ligand-linker building block for PROTAC synthesis.
Molecular formula C38H59ClN4O7S.
Molecular weight 751.42 g/mol.
Purity ≥95.0% (manufacturer assay).
Supplied as a 500 mg solid.
Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).

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1,991

Medchemexpress LLC Bis-PEG5-acid 5g | 439114-13-3 | 338.35 g·mol⁻1 | C14H26O9 | 5 G

Bis-PEG5-acid is a polyethylene glycol (PEG)-based bifunctional linker with two terminal carboxylic acid groups, used as a hydrophilic spacer in PROTAC synthesis, bioconjugation, and medicinal chemistry to improve solubility and provide flexibility between binding motifs.

Provides a flexible PEG5 spacer for conjugation and linker design.
Two terminal carboxylic acid groups for straightforward coupling chemistry.
High purity (99.9%) suitable for research applications.
Available in laboratory pack sizes for small-scale synthesis.
Enhances aqueous solubility of hydrophobic ligands and intermediates.

Pricing & Availability

1,992

Medchemexpress LLC 1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- | 4246-51-9 | >99.9% | 100 G

Bis-NH2-C1-PEG3, also known as PROTAC Linker 24, is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.

PEG-based PROTAC linker
Used in the synthesis of PROTACs
Appearance: colorless to light yellow liquid
Molecular formula: C10H24N2O3
Molecular weight: 220.31
Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)

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1,993

Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 25 MG

AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM. It inhibits the ID2-KDR signaling axis, leading to the down-regulation of downstream angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9), while up-regulating the tumor suppressor factor (PTEN). It can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and demonstrates significant cancer-suppressing potency. This compound is used for the study of glioma.

Potent DNA binding inhibitor 2 (ID2) antagonist
Inhibits cell migration and invasion of glioma cell lines
Induces apoptosis
Demonstrates significant cancer-suppressing potency
Inhibits ID2-KDR signaling axis
Down-regulates angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9)
Up-regulates tumor suppressor factor (PTEN)
Suitable for the study of glioma

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1,994

Apexbio Technology LLC PS-1145 431898-65-6 25mg

PS-1145 (CAS 431898-65-6) is a selective inhibitor of I B kinase (IKK) with an IC50 of 88 nM IKK is a critical component of the upstream NF- B signaling pathway regulating cellular responses to inflammation In vitro studies have demonstrated that PS-1145 blocks TNF -induced NF- B activation in multiple myeloma (MM) cells in a dose- and time-dependent manner increases I B protein levels suppresses IL-6-mediated anti-apoptotic effects and inhibits expression of ICAM-1 Additionally PS-1145 reduces IL-6 secretion from bone marrow stromal cells (BMSCs) and partially limits MM cell proliferation In vivo PS-1145 has been shown to induce apoptosis in DMBA-induced skin tumors in rats by inhibiting NF- B and VEGF activity The compound remains in the preclinical research stage

Pricing & Availability

1,995

eMolecules 280752-78-5 | (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol | MFCD10699559 | 250mg

Medchem Express | Delphinidin 3-glucoside (chloride) | 1mg | 632433155 | HY-108052 | 6906-38-3 | MFCD01762899 | 500.840 | C21H21ClO12

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Organo-Metalloid Compounds

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Medchemexpress LLC Azido-PEG3-C3-OH | 1807512-36-2 | 98.0% | C9H19N3O4 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | >95.0% | C19H32N2O5 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5,8,11-Trioxa-2,14-diazahexadecanoic acid, 16-bromo-15-oxo-, 1,1-dimethylethyl ester | 1421933-39-2 | ≥98.0% | C15H29BrN2O6 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DPC-681 | 284661-68-3 | 99.7% | 669.85 | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 50 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC SX-682 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S,R,S)-Ahpc-C6-Peg3-C4-Cl | 1835705-55-9 | MFCD31560478 | ≥95.0% | 751.42 g/mol | C38H59ClN4O7S | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bis-PEG5-acid 5g | 439114-13-3 | 338.35 g·mol⁻1 | C14H26O9 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- | 4246-51-9 | >99.9% | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC PS-1145 431898-65-6 25mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More