Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 4,7,10,13-tetraoxatetradecanoic acid | 67319-28-2 | 97.0% | 236.26 | C10H20O6 | 1 G
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m-PEG3-CH2CH2COOH is a monomethyl-terminated PEG3 linker bearing a terminal carboxylic acid, used as a non-cleavable linker in antibody-drug conjugate and PROTAC synthesis. It is supplied as a colorless to light yellow liquid with a high NMR purity and defined molecular properties.
- Monomethyl-terminated PEG3 linker
- Terminal carboxylic acid functionality for conjugation
- Suitable for ADC and PROTAC synthesis
- Colorless to light yellow liquid form
- 97.0% purity (NMR)
- Molecular weight 236.26; formula C10H20O6
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Medchemexpress LLC Pc biotin-PEG3-azide | 1937270-46-6 | 97.8% | 825.93 g/mol | C35H55N9O12S | 10 MG
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PC Biotin-PEG3-azide is a cleavable three-unit polyethylene glycol (PEG3) biotinylated azide linker used for bioconjugation and the synthesis of antibody-drug conjugates. It contains an azide functional group for click chemistry and reacts in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Cleavable three-unit PEG linker.
- Contains an azide functional group for click chemistry.
- Suits copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- High research-grade purity.
- Available in small-scale quantities for conjugation workflows.
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Medchemexpress LLC m-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 500 MG
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m-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker, where one ligand is for an E3 ubiquitin ligase and the other targets a specific protein.
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC T-Boc-aminooxy-PEG5-azide | 2250216-95-4 | 95.0% | C17H34N4O8 | 50 MG
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t-Boc-Aminooxy-PEG5-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group for reactions
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Bis-aminooxy-PEG3 | 98627-70-4 | 98.0% | C8H20N2O5 | 50 MG
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Bis-aminooxy-PEG3 (CAS: 98627-70-4) is a chemical compound with the molecular formula C8H20N2O5 and a molecular weight of 224.25. It is typically a colorless to light yellow liquid. This product is intended for research use only.
- Purity of 98.0% by NMR
- Store at 4°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Appearance is a colorless to light yellow liquid
- Chemical structure consistent with 1H NMR and MS analysis
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Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.35% | 508.56 | 50 MG
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DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It features a DBCO group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Non-cleavable 3 unit PEG ADC linker.
- Used in the synthesis of antibody-drug conjugates (ADCs).
- Contains a DBCO group.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
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Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | C28H36N8O10 | 1 MG
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Folate-PEG3-C2-acid is a specialized acid fragment derived from Folate-PEG3-NHS ester, designed as a PEG-type PROTAC linker. This compound is crucial for the synthesis of PROTAC (PROteolysis TArgeting Chimera) molecules, which are heterobifunctional molecules that induce the degradation of target proteins. Its molecular structure facilitates the creation of complex PROTACs, enabling advanced research in targeted protein degradation.
- PEG-type PROTAC linker
- Acid fragment of Folate-PEG3-NHS ester
- Essential for synthesizing PROTAC molecules
- Purity of 97.56% ensures reliable experimental results
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Medchemexpress LLC Mal-amido-PEG3-acid | 2055353-75-6 | 98% | 372.37 | 100 MG
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Mal-amido-PEG3-acid | 2055353-75-6 | 372.37 | 1G
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA | 2414913-97-4 | 99.0% | 2 G
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Pomalidomide-PEG3-C2-NH2 TFA is a synthetic E3 ligase ligand-linker conjugate, featuring a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is designed for the synthesis of PROTACs and is intended for research use only.
- Synthetic E3 ligase ligand-linker conjugate
- Features a Pomalidomide-based cereblon ligand and 3-unit PEG linker
- Utilized for the synthesis of PROTACs
- High purity: 99.0%
- Molecular weight: 562.49
- Chemical formula: C23H29F3N4O9
- Appears as a light yellow to yellow solid-liquid mixture
- Soluble in DMSO, ethanol, and water
- Offers multiple dissolution protocols for in vivo studies
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Medchemexpress LLC Acetic acid, 2-(2,4-dichlorophenoxy)-, isooctyl ester | 25168-26-7 | 97.2% | 250 MG
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2,4-D isooctyl ester is a selective herbicide belonging to the chlorophenoxy compound class. It is characterized by a higher boiling point, low volatility, and low drift, making it effective for controlling broadleaf weeds in various settings such as crops, lawns, and forests. This product is for research use only.
- Selective herbicide
- Chlorophenoxy compound
- Higher boiling point, low volatility, and low drift
- Controls broadleaf weeds
- Suitable for use in crops, lawns, and forests
- Purity: 97.17%
- Molecular formula: C16H22Cl2O3
- Molecular weight: 333.25
- Appearance: Colorless to light yellow liquid
- Soluble in DMSO (≥ 175 mg/mL)
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Medchemexpress LLC 5,8,11-trioxa-2-azatetradecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 867062-95-1 | 99.8% | 443.49 g/mol | C24H29NO7 | 1 G
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Fmoc-NH-PEG3-CH2CH2COOH is an Fmoc-protected PEG3 linker bearing a terminal carboxylic acid, used in research applications as a cleavable linker for antibody-drug conjugates and as a PEG-based linker for PROTAC synthesis.
- Fmoc-protected amine functionality for standard peptide chemistry
- Terminal carboxylic acid for conjugation
- High reported purity (≈99.8%)
- Molecular weight 443.49 g/mol
- Chemical formula C24H29NO7
- Available in small-scale quantities, including 1 G
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Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 50 MG
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups or strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Contains an azide group, facilitating click chemistry reactions.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 10 G
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THP-PEG3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are compounds that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein.
- PEG-based PROTAC linker
- Molecular formula: C11H22O5
- Molecular weight: 234.29
- Appearance: Liquid
- Color: Colorless to light yellow
- For research use only
- Target: PROTAC linkers
- Pathway: PROTAC
- Storage (pure form): -20°C for 3 years; 4°C for 2 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 99.2% | 810.01 g·mol⁻¹ | C42H59N5O9S | 10 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL E3 ligase ligand-linker conjugate used as a building block in the synthesis of PROTACs and other conjugates. It features a PEG3 spacer and a bicyclononyne (BCN) functional group to facilitate bioorthogonal conjugation and assembly of bifunctional molecules for targeted protein degradation research.
- VHL E3 ligase ligand for targeted protein degradation applications.
- PEG3 linker provides a flexible spacer for molecular conjugation.
- BCN functional group enables strain-promoted bioorthogonal click conjugation.
- Reported high purity suitable for synthetic chemistry use.
- Intended as a small-molecule building block for PROTAC assembly and conjugation workflows.
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