Prenol lipids
Medchemexpress LLC Antioxidant agent-15 | 596-38-3 | 98.97% | 274.31 | 100 MG
Antioxidant agent-15 (Compound 4) is a potent antioxidant with an inhibition activity IC50 of 15.44 nM. It inhibits tumor cell growth in Hela, Hep G2, and Caco-2 cells, with IC50 values of 395.26, 400.4, and 24.6 nM, respectively.
- Potent antioxidant inhibition activity (IC50 = 15.44 nM).
- Inhibits tumor cell growth in Hela, Hep G2, and Caco-2 cells.
- Available in solid, white to off-white appearance.
- Soluble in DMSO (100 mg/mL).
Apexbio Technology LLC Phytol 150-86-7 250g
Phytol is a naturally occurring diterpene alcohol derived from chlorophyll metabolism serving as an activator for retinoid X receptors (RXRs) RXRs are nuclear hormone receptors implicated in transcriptional regulation and cellular differentiation through ligand-dependent signaling pathways involving vitamins and hormones Phytol activates RXRs displaying Ki values ranging from 2 3 to 67 2 M In mammals phytol is metabolized to phytanic acid a reaction regulated by peroxisome proliferator-activated receptor (PPAR ) Additionally phytol interacts with GABA A receptors exhibiting sedative and anxiolytic properties and has been investigated as an antischistosomal candidate in animal models
Medchemexpress LLC Antioxidant agent-1 | 136068-43-4 | 98.1% | C15H12O3 | 25 MG
Antioxidant agent-1 is a novel chalcone derivative, recognized as a potential antioxidant. This compound is suitable for laboratory research and substance manufacturing applications.
- Functions as a potential antioxidant agent
- Demonstrates inhibitory activity against 5-lipoxygenase (IC50 of 0.043 μM)
- Exhibits inhibitory activity against cyclooxygenase (IC50 of 0.043 μM)
- Effective in KB cells with a CC50 of 3.1 μM
- Effective in MT4 cells with a CC50 of 1.7 μM
Sigma Aldrich Fine Chemicals Biosciences Citral natural, >=96%, FCC, FG | 5392-40-5 | MFCD00006997 |
Citral natural, >=96%, FCC, FG | Purity: >=96% | Mol Wt: 152.23 | 5392-40-5 | MFCD00006997 |
Sigma Aldrich Fine Chemicals Biosciences Citral | 5392-40-5 | MFCD00006997 | 1 kg
Citral | Purity: ≥96% | Mol Wt: 152.23 | 5392-40-5 | MFCD00006997 | 1 kg
Medchemexpress LLC Lupeol | 545-47-1 | 426.72 | 50 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity. It is a potent androgen receptor (AR) inhibitor and is utilized for cancer research, particularly for prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC).
- Active pentacyclic triterpenoid.
- Anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity.
- Potent androgen receptor (AR) inhibitor.
- Used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC).
Medchemexpress LLC (rel)-ML-SI3 | 2108567-79-7 | 98.9% | 429.58 | 25 MG
(rel)-ML-SI3 is one of the active ingredients of ML-SI3 (HY-139426), targeting three isoforms of TRPML. It functions as an inhibitor of TRPML1 and TRPML3, and a potent activator of TRPML2.
- Targets three isoforms of TRPML
- Inhibitor of TRPML1 and TRPML3
- Potent activator of TRPML2
- Supplied as a white to off-white solid
eMolecules Ambeed / 4-Isopropylbenzoic acid / 5g / 552678204 / A255165 / / 536-66-3 / MFCD00002564 / 164.204 / C10H12O2
Ambeed / 4-Isopropylbenzoic acid / 5g / 552678204 / A255165 / / 536-66-3 / MFCD00002564 / 164.204 / C10H12O2
Medchemexpress LLC Catalpol | 2415-24-9 | 362.33 | 50 MG
Catalpol is an iridoid glycoside found in *Rehmannia glutinosa*. It exhibits various effects including neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant, and anti-HBV effects.
- Found in *Rehmannia glutinosa*
- Exhibits neuroprotective effects
- Exhibits hypoglycemic effects
- Exhibits anti-inflammatory effects
- Exhibits anti-cancer effects
- Exhibits anti-spasmodic effects
- Exhibits anti-oxidant effects
- Exhibits anti-HBV effects
- Induces neuronal differentiation in PC12 cells
- Promotes neurite length
- Reduces blood urea nitrogen in renal ischemia/reperfusion injury (IRI) mice
- Reduces serum creatinine levels in IRI mice
- Reduces KIM-1 expression in IRI mice
- Suppresses PI3K, Akt, eNOS levels
- Suppresses TNF-α, IL-1β, IL-6, and IL-10 activities
Medchemexpress LLC Icatibant acetate (HOE 140 acetate) | 138614-30-9 | 99.9% | 1364.57 | 25 MG
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively.
- Potent and specific peptide antagonist of bradykinin B2 receptor.
- IC50 and Ki of 1.07 nM and 0.798 nM respectively for bradykinin B2 receptor.
- For research use only.
Medchemexpress LLC Resomelagon acetate (AP1189 acetate) | 1809420-72-1 | MFCD00000305 | 99.8% | 358.35 | 5 MG
Resomelagon acetate (AP1189 acetate) is a potent, orally active melanocortin receptor (MR) agonist, specifically targeting MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization, exhibiting anti-inflammatory activity. This compound is applicable for research in obesity and chronic inflammation.
- Potent, orally active melanocortin receptor agonist
- Specifically targets MC1 and MC3
- Induces ERK1/2 phosphorylation and Ca2+ mobilization
- Exhibits anti-inflammatory activity
- Inhibits TNF-α release and efferocytosis
- Promotes resolution of acute inflammation
- Reduces arthritis in mice
AdipoGen Genipin
Chemical. CAS 6902-77-8. Formula C11H14O5. MW 226.2. Isolated from Gardenia jasminoides Ellis fruits. Cell permeable inhibitor of uncoupling protein 2 UCP2. Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Anticancer, antimetastatic and anti-angiogenic agent. Increases Bax/Bcl-2 ratio and induces PARP cleavage and caspase-3- and caspase-9-mediated apoptosis in non-small cell lung cancer NSCLC cells. Sensitizes multidrug-resistant cancer cells to cytotoxic agents through UCP2 inhibition. Suppresses the tumor promoting function of UCP2 in a cellular model of Warburg effect. Anti-inflammatory agent. Upregulates nNOS neuronal nitric oxide synthase/NOS I and decreases acute inflammation through inhibition of LPS-induced NF-kappaB activity. Inhibits toll-like receptor TLR signaling and the production of pro-inflammatory cytokines, preventing sepsis and increasing survival in animal models of infection.
Sigma Aldrich Fine Chemicals Biosciences (-)-alpha-Terpineol natural, >=96%, FCC, FG | 10482-56-1 | MFCD00075926 |
(-)-alpha-Terpineol natural, >=96%, FCC, FG | Purity: >=96% | Mol Wt: 154.25 | 10482-56-1 | MFCD00075926 |
Medchemexpress LLC Nab-Paclitaxel 5mg | 5mg
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015) Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability Nab-Paclitaxel displays less toxicity and greater antitumor activity Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma seven neuroblastoma cell lines and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors (The product specifications below only indicate the effective content of Paditaxel the actual albumin quality depends on the batch the ratio of each ingredient in this product is Paditaxel albumin -1 7 1 11)[1][2]