Prenol lipids
Medchemexpress LLC Alpha-Tocopherol | 59-02-9 | MFCD00006848 | 430.71 | 5 G
α-Vitamin E ((+)-α-Tocopherol) is a naturally occurring, potent antioxidant and peroxyl radical scavenger. It maintains the integrity of long-chain polyunsaturated fatty acids in cell membranes. It inhibits PKC, leading to inhibition of platelet aggregation and modulation of nitric oxide and superoxide production. It also activates MAP kinase and PI3 kinase (PI3K) pathways and has proposed benefits for influenza virus A, hepatitis B, and hepatitis C infections.
- Potent antioxidant
- Peroxyl radical scavenger
- Inhibits PKC in various cell types
- Induces activation of MAP kinase and PI3 kinase (PI3K) pathways
- Prevents increase in pro-inflammatory cytokines IL-1, IL-6, and IFN-γ mRNA and protein
- Ameliorates diabetic nephropathy in mice
- Appearance: Liquid (density: 0.95 g/cm³)
- Color: Colorless to light yellow
- Initial source: Endogenous metabolite
- Purity: 99.67%
Medchemexpress LLC α-Vitamin E (standard) | 59-02-9 | 430.71 | 50 MG
α-Vitamin E (Standard) is the analytical standard of α-Vitamin E, intended for research and analytical applications. This naturally occurring form of vitamin E is a potent antioxidant, supplied as a reference standard assay.
- Analytical standard of α-Vitamin E.
- Intended for research and analytical applications.
- Potent antioxidant.
- Reference standard supplied assay.
- Commonly used in HPLC, GC, and MS experiments.
Medchemexpress LLC Antioxidant agent-4 | 50901-34-3 | 96.0% | 168.15 g/mol | C8H8O4 | 100mg
Antioxidant agent-4 is a small-molecule antioxidant reported to have antilipid peroxidative activity. It is supplied as a solid for laboratory research use only and is not intended for clinical or human use.
- Small-molecule antioxidant with antilipid peroxidative activity.
- Available in multiple pack sizes, including 100 mg.
- Purity listed as 96.0%.
- Molecular formula C8H8O4 and molecular weight 168.15 g/mol.
- Intended for biochemical and cellular research applications.
Medchemexpress LLC D-α-Tocopherol acetate (D-vitamin E acetate) | 58-95-7 | 98.3% | 10 G
D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine. It is intended for research use only.
- Can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine.
- Inhibits production of NO, prostaglandin E2, and pro-inflammatory cytokines in mouse peritoneal macrophages.
- Exhibits a slight suppression on the activation of NF-κB p50 and p65.
Medchemexpress LLC Glutarylcarnitine-d9 chloride | 95.0% | 320.81 g/mol | C12H13D9ClNO6 | 5 MG
Deuterium-labeled glutarylcarnitine chloride supplied as a 5 mg analytical standard for use as an internal standard in mass spectrometry and quantitative metabolite analysis. Provided as an oil with stated purity.
- Deuterium-labeled internal standard for glutarylcarnitine.
- Suitable for mass spectrometry and quantitative assays.
- 5 mg package size for calibration and method development.
- High purity (95.0%) to support accurate quantitation.
- Chloride salt provided in oil form for stability.
- Molecular weight 320.81 g/mol; formula C12H13D9ClNO6.
Medchemexpress LLC (rel)-AR234960 | 1408311-94-3 | HY-120006A | 98.95% | 555.62 | 10 MG
(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. It activates the downstream ERK1/2 signaling pathway, leading to the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes. This compound promotes collagen synthesis in cardiac fibroblasts via the MAS-ERK1/2-CTGF pathway and exacerbates extracellular matrix remodeling. It regulates the expression of cardiac fibrosis-related genes and can be utilized in heart failure research.
- Selective and competitive MAS receptor agonist
- Activates ERK1/2 signaling pathway
- Induces CTGF and collagen gene expression
- Promotes collagen synthesis in cardiac fibroblasts
- Regulates cardiac fibrosis-related genes
- Useful in heart failure research
Cayman Chemical TNFRSF8CD30 LNg Isoform EX
Source: Active recombinant C-terminal human IgG1 Fc-His-tagged CD30 expressed in HEK293 cells • Amino acids: 19-379 • MW: 66.5 kDa
Medchemexpress LLC Cetrorelix acetate | 145672-81-7 | 98.3% | 1491.09 | 25 MG
Cetrorelix Acetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist. It exhibits an IC50 of 1.21 nM and is utilized in various research applications, including studies on cancer cells and clinical trials for conditions such as polycystic ovarian syndrome and infertility.
- Potent GnRH receptor antagonist
- IC50 of 1.21 nM against GnRH
- Inhibits growth of ES-2 cell line at 1000 ng/ml
- Soluble in DMSO (50 mg/mL)
- Soluble in H2O (2 mg/mL)
- White to off-white solid appearance
- Molecular formula C72H96ClN17O16
- Long-term storage as powder at -80°C for 2 years or -20°C for 1 year
- Long-term storage in solvent at -80°C for 6 months or -20°C for 1 month
Apexbio Technology LLC Ulipristal acetate 126784-99-4 5mg
Ulipristal acetate (126784-99-4) is a selective progesterone receptor modulator (SPRM) targeting progesterone receptors It is designed to modulate receptor-mediated signaling thereby regulating endometrial tissue proliferation and fibroid cell growth Ulipristal acetate exerts its biological activity primarily through reversible inhibition of progesterone-dependent signaling pathways Based on these pharmacological properties ulipristal acetate holds research potential in studies of progesterone signaling pathways uterine physiology hormonal regulation mechanisms and benign gynecological conditions such as uterine myoma
TARGETMOL CHEMICALS INC BETA-TOCOPHEROL 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Beta-Tocopherol shows effect on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA). purity: 99%
Cayman Chemical VItamIn K1 2 3-epoxIde 1mg
The inactive metabolite of vitamin K1 formed during blood clotting that is rapidly reduced back to vitamin K1 by a microsomal epoxide reductase
Medchemexpress LLC DL-alpha-Tocopherol 5g | 1309573-60-1 | 5 G
DL-alpha-tocopherol methoxypolyethylene glycol succinate is a vitamin E-derived amphiphilic surfactant and solubilizing agent supplied as an aqueous solution for research use; it is used to aid solubilization, improve reaction performance, and support stability testing of modified drugs.
- Acts as an amphiphilic surfactant and solubilizer.
- Improves aqueous solubility of lipophilic compounds.
- Enhances aqueous cross-coupling reaction performance (Suzuki-Miyaura reported).
- Used for stability testing of modified drugs in biological fluids.
- Typically provided as an aqueous solution at about 20 mg/mL.
AdipoGen Betulinic acid 97
Chemical. CAS 472-15-1. Formula C30H48O3. MW 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.
TARGETMOL CHEMICALS INC URSONIC ACID 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor. purity: 99%