Prenol lipids

Apexbio Technology LLC nor-NOHA (acetate) 1140844-63-8 5mg

nor-NOHA (acetate) (CAS 1140844-63-8) is a potent reversible inhibitor of rat liver arginase (Ki 0 5 M) By competitively inhibiting arginase nor-NOHA modulates the cellular balance between the L-arginine-dependent pathways of nitric oxide synthase (NOS) and arginase affecting nitric oxide production and urea cycle metabolism In vitro studies have shown that nor-NOHA suppresses proliferation migration and invasion of HepG2 hepatocellular carcinoma cells induces apoptosis and alters expression of Arg1 MMP-2 P53 and ECD In vivo nor-NOHA improves endothelial function in rat models of inflammation by enhancing NOS activity increasing EDHF and reducing superoxide anion production This compound is widely used to investigate arginase-related mechanisms in cellular and vascular biology

Medchemexpress LLC Nor-NOHA acetate | 1140844-63-8 | ≥99.0% | 296.28 g/mol | C9H20N4O7 | 5 MG

nor-NOHA acetate (Nω-hydroxy-nor-L-arginine acetate) is a research-grade, selective and reversible arginase inhibitor used to study endothelial dysfunction, immunosuppression, apoptosis, and metabolic pathways. Supplied as the acetate salt in solid and solution formats for laboratory research; intended for in vitro studies.

• Selective and reversible arginase inhibitor.
• Induces apoptosis in ARG2-expressing cells under hypoxia; useful in endothelial dysfunction and immunosuppression research.
• Supplied as acetate salt in solid (1 mg, 5 mg, 10 mg, 50 mg) and solution (10 mM in water, 1 mL) formats.
• High purity (≥99.0%).
• Molecular weight 296.28 g/mol; molecular formula C9H20N4O7.
• For research use only; not for human or clinical use.