Acyl Halides
Medchemexpress LLC Sofpironium bromide | 1628106-94-4 | 98.26% | 470.40 | 50 MG
Sofpironium bromide is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). It reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site and also has a high affinity for the M1, M2, M4, and M5 subtypes. Sofpironium bromide is metabolized mainly through non-enzymatic hydrolysis, and also through oxidative metabolism via CYP2D6 and CYP3A4. In a rat model, it reduces footpad sweating induced by Pilocarpine (a muscarinic receptor agonist). It exhibits anticholinergic activity by inhibiting the contractile activity of guinea pig ileal tissue in a concentration-dependent manner.
- Reduces sweating by inhibiting M3 muscarinic receptors
- High affinity for M1, M2, M4, and M5 muscarinic receptor subtypes
- Metabolized mainly through non-enzymatic hydrolysis
- Exhibits anticholinergic activity
Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | MFCD00149575 | >98.0% | 373.4 g/mol | C17H19N5O5 | 5 G
N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analog of deoxyadenosine bearing an N6-benzoyl protecting group. It is provided as a monohydrate solid for research use (CAS 305808-19-9) with purity ≥98.0%, and is used as an intermediate in nucleoside chemistry, oligonucleotide synthesis, and studies of nucleoside analog activity.
- High purity suitable for research applications.
- Monohydrate solid form for stable handling and storage.
- Serves as an intermediate in nucleoside and oligonucleotide synthesis.
- Compatible with standard analytical and synthetic workflows.
- Supplied in small-scale laboratory pack sizes for bench use.
Medchemexpress LLC Cetrimonium bromide | 57-09-0 | 98.0% | 500 MG
Cetrimonium bromide (CTAB) is a quaternary ammonium, orally active cationic surfactant. It exhibits toxicity and anticancer effects. It inhibits cell migration and invasion by modulating canonical and non-canonical TGF-β signaling pathways. Cetrimonium bromide can also be used for DNA extraction.
- Cationic surfactant
- Exhibits toxicity and anticancer effects
- Inhibits cell migration and invasion by modulating canonical and non-canonical TGF-β signaling pathways
- Can be used for DNA extraction
- Does not affect growth of SK-HEP-1 cells at 1-5 μM for 24 hours
- Attenuates cellular migration and invasion of SK-HEP-1 cells at 5 μM for 16-24 hours
- Inhibits protein expression of MMP-2 and MMP-9, increases TIMP-1 and TIMP-2, and restrains Rac1, cdc42, and RhoA in SK-HEP-1 cells at 5 μM for 24 hours
- Induces apoptosis in human head and neck cancer (HNC) cells at 5 μM for 12-72 hours
Medchemexpress LLC Benzenepropanoic acid, ß-(benzoylamino)-α-hydroxy-, (αR,βS)- | 132201-33-3 | 1 ML
N-Benzoyl-(2R,3S)-3-phenylisoserine is a crucial Taxol C-13 side chain, vital for the potent antitumor activity of Taxol. This product is intended for research and analytical applications.
- Taxol C-13 side chain
- Crucial for strong antitumor activity
- High purity (99.48%)
eMolecules Chem-Impex Copper(II) bromide 5kg 342449732 24557 0 000 7789-45-9 MFCD00010970 223 354 Br2Cu
Chem-Impex Copper(II) bromide 5kg 342449732 24557 0 000 7789-45-9 MFCD00010970 223 354 Br2Cu
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 10mM (in 1mL DMSO)
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Medchemexpress LLC Sofpironium bromide | 1628106-94-4 | 98.3% | 470.40 | 25 MG
Sofpironium bromide is an anticholinergic agent that has been studied for its use in treating primary axillary hyperhidrosis (PAH). It works by inhibiting M3 muscarinic receptors in the eccrine glands at the application site, thereby reducing sweating. The compound also demonstrates high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes.
- Anticholinergic agent
- Used in the study of primary axillary hyperhidrosis (PAH)
- Reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site
- Demonstrates high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes
Sigma Aldrich Fine Chemicals Biosciences Nalpha Benzoyl L arginine250MG
NBenzoyl-L-arginine 4-nitroanilide hydrochloride is a substrate for trypsin.
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 10 MG
Fentonium bromide is an anticholinergic, antispasmodic, and anti-ulcerogenic research chemical used in studies of neurological conditions such as unstable bladder. It is supplied for laboratory research in small solid quantities.
- Purity 98.8%.
- Molecular weight 564.51 g/mol.
- Chemical formula C31H34BrNO4.
- Available in milligram-scale solid quantities for research use.
- Used in research on anticholinergic activity and bladder instability.
Medchemexpress LLC 2-bromoisobutyryl bromide | 20769-85-1 | MFCD00000122 | ≥98.0% | 229.90 | C4H6Br2O | 50g
2-Bromoisobutyryl bromide (Bromodimethylacetyl bromide -Bromoisobutyryl bromide 2-Bromoisobutylyl bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]
Medchemexpress LLC N4-Benzoyl-2 -O-meth 1g
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]