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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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Bromo-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Peg-based PROTAC linker
Used in the synthesis of PROTACs
PROTACs exploit the intracellular ubiquitin-proteasome system
PROTACs selectively degrade target proteins
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Diamine oxidase from porcine kidney is a homodimer consisting of two equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose 3.3% glucosamine 2.6% N-acetylglucosamine and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(±)-WB 4101 hydrochloride is a potent antagonist of noradrenaline. It interacts with protein in smooth muscle, promoting tight binding between the drug and receptor.
Potent antagonist of noradrenaline
Interacts with protein in smooth muscle
Promotes tight binding between the drug and receptor
Store solid form at -20°C, sealed, away from moisture
Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
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