Alkyl Halides
![Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000095535.png-250.jpg)
Apexbio Technology LLC hemagglutinin precursor (114-122) amide [Influenza A virus] 5mg
Hemagglutinin precursor 114-122 amide is a synthetic peptide fragment derived from the hemagglutinin glycoprotein of Influenza A virus It is designed to present antigenic determinants that facilitate the analysis of peptide-MHC interactions and characterization of influenza-specific immune responses Hemagglutinin precursor 114-122 amide exerts its biological activity primarily by eliciting immune responses against Influenza A virus supporting studies on cytotoxic T-cell reactivity and antigenicity Based on these properties hemagglutinin precursor 114-122 amide holds research potential in immunological assays vaccine antigenicity studies and investigations of antiviral immune responses
Medchemexpress LLC Antifungal agent 112 | 68380-53-0 | 99.5% | 287.32 | 25 MG
Antifungal agent 112 (Compound 1e) exhibits antifungal activity against *Candida albicans*, *Aspergillus niger*, and *Aspergillus fumigatus* with MIC values of 0.0024, 0.0022, and 0.0028 M, respectively. It is for research use only and not sold to patients.
- Antifungal activity against *Candida albicans*, *Aspergillus niger*, and *Aspergillus fumigatus*.
- Available in various quantities (5 mg, 10 mg, 25 mg, 50 mg).
- Controlled substance, not for sale in all territories.
Medchemexpress LLC Spi-112 | 1051387-90-6 | MFCD31620831 | 98.0% | 468.46 g/mol | C22H17FN4O5S | 1 ML
SPI-112 is a potent, selective, and competitive inhibitor of SHP2 (PTPN11) used for in vitro biochemical and biophysical studies. It inhibits SHP2 with an IC50 of approximately 1 μM, with weaker activity against related phosphatases. Kinetic and binding data indicate competitive inhibition (Ki ≈ 0.8 μM) and 1:1 binding by SPR (KD ≈ 1.3 μM). The compound is not cell permeable and is supplied for research applications.
- Inhibits SHP2 with IC50 ≈ 1 μM.
- Shows selectivity over related phosphatases (IC50s 18.3 μM for PTP, 14.5 μM for PTP1B).
- Exhibits competitive inhibition kinetics (Ki ≈ 0.8 μM).
- Binds 1:1 in SPR with KD ≈ 1.3 μM.
- Not cell permeable due to polar or charged functional groups.
- Supplied as a solid and as a 10 mM solution for in vitro assays.
- High purity suitable for biochemical assays (≈98%).
- Store solid at 4°C; in solvent store at -80°C (long term) or -20°C (short term).
Apexbio Technology LLC I-CBP 112 1640282-31-0 5mg
I-CBP 112 (CAS 1640282-31-0) is a selective small-molecule inhibitor targeting the bromodomains of CREBBP (CBP) and EP300 two epigenetic regulators involved in transcriptional control In biochemical assays I-CBP 112 demonstrates an IC50 of 170 nM against CREBBP with marked selectivity over other bromodomain-containing proteins such as ATAD2 BAZ2B and members of the BET family In vitro studies indicate that I-CBP 112 does not exhibit significant cytotoxicity in U2OS cells at concentrations up to 50 M Currently this compound is utilized predominantly in cellular and molecular studies to dissect the function of CREBBP/EP300 bromodomains in gene regulation with ongoing use limited to preclinical in vitro research contexts
Medchemexpress LLC UC-112 | 383392-66-3 | 98.9% | 100 MG
UC-112 is a survivin and XIAP modulator exhibiting anticancer activity. It functions by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal pathway. This compound also effectively reduces XIAP levels in in vivo tumor models, leading to the activation of caspase-3/7 and caspase-9, and ultimately inducing apoptosis in cancer cells. It is suitable for research on melanoma, prostate cancer, and other cancer-related studies.
- Selectively downregulates and degrades survivin
- Reduces XIAP levels in in vivo tumor models
- Activates caspase-3/7 and caspase-9
- Induces cancer cell apoptosis
- Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
- Alters cell cycle distribution in A375 melanoma cells
- Inhibits human melanoma tumor growth in nude mice
![Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264388.png-250.jpg)
Medchemexpress LLC 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol | 383392-66-3 | 98.9% | 348.44 | C22H24N2O2 | 5 MG
UC-112 is a small-molecule inhibitor of inhibitor of apoptosis proteins (IAP) developed for cellular studies of apoptosis and anticancer activity. It produces cytotoxic and antiproliferative effects across multiple human cancer cell lines and is supplied as a solid or as a DMSO solution for research applications.
- Potent IAP inhibitor with reported cell-assay IC50 = 0.7-3.4 μM.
- Demonstrated activity in PC-3, A-375, M14, and DU-145 cell lines.
- High purity (98.92%) suitable for in vitro studies.
- Molecular formula C22H24N2O2; molecular weight 348.44.
- Available as milligram quantities and as a 10 mM solution in DMSO.
- Intended for research use in apoptosis and anticancer mechanism studies.
eMolecules Key Organics/BIONET 2 4-dichloro-3-(trifluoromethyl)pyridine 10mg 564136012 HD-0214 97 000 1186194-98-8 MFCD12547046 215 980 C6H2Cl2F3N
Key Organics/BIONET 2 4-dichloro-3-(trifluoromethyl)pyridine 10mg 564136012 HD-0214 97 000 1186194-98-8 MFCD12547046 215 980 C6H2Cl2F3N
Medchemexpress LLC hsa-miR-122-5p mimic 20nmol | 20nmol
hsa-miR-122-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
Medchemexpress LLC Antifungal agent 112 | 68380-53-0 | 99.5% | 287.32 | 50 MG
Antifungal agent 112 (Compound 1e) demonstrates antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus fumigatus with Minimum Inhibitory Concentrations (MIC) of 0.0024 M, 0.0022 M, and 0.0028 M, respectively. This product is for research use only and is not intended for patient use.
- Exhibits antifungal activity against Candida albicans
- Exhibits antifungal activity against Aspergillus niger
- Exhibits antifungal activity against Aspergillus fumigatus
- Minimum inhibitory concentrations of 0.0024 M, 0.0022 M, and 0.0028 M against specific fungi
- Intended for research use only
eMolecules ChemScene / 2-(2-(Benzyloxy)phenyl)acetic acid / 250mg / 632297018 / CS-0156164 / 0.000 / 22047-88-7 / MFCD00016822 / 242.274 / C15H14O3
ChemScene / 2-(2-(Benzyloxy)phenyl)acetic acid / 250mg / 632297018 / CS-0156164 / 0.000 / 22047-88-7 / MFCD00016822 / 242.274 / C15H14O3