Aryl halides

eMolecules​ 4-BROMO-5-FLUOROPYRIMIDINE | 1003706-87-3 | MFCD09955612 | 1g

AstaTech | 4-BROMO-5-FLUOROPYRIMIDINE | 1g | 475589580 | 77431 | 97.000 | 1003706-87-3 | MFCD09955612 | 176.976 | C4H2BrFN2

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Medchemexpress LLC 6-Methoxyquinoline | 5263-87-6 | MFCD00006800 | 100.0% | 159.19 g/mol | C10H9NO | 5 G

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6-Methoxyquinoline is an aromatic quinoline derivative used as a biochemical assay reagent and a synthetic intermediate. It is supplied with solubility and storage guidance for laboratory handling.

• Aromatic quinoline derivative suitable for biochemical assays and organic synthesis.
• Molecular formula C10H9NO; molecular weight 159.19 g/mol.
• Reported purity 99.99% for research applications.
• Soluble in DMSO at 200 mg/mL; sonication may be required.
• Storage stability: 3 years at room temperature; in solvent, 2 years at -80°C and 1 year at -20°C.
• CAS number 5263-87-6 for unambiguous identification.

Apexbio Technology LLC 4-iodo-SAHA 1219807-87-0 250mg

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4-iodo-SAHA (CAS 1219807-87-0) is a hydrophobic analog of suberoylanilide hydroxamic acid (SAHA) that functions as a histone deacetylase (HDAC) inhibitor targeting both class I and II HDACs By blocking HDAC activity 4-iodo-SAHA modulates the reversible acetylation of lysine residues on histone and non-histone proteins affecting transcriptional regulation In cellular assays 4-iodo-SAHA demonstrated antiproliferative effects with EC50 values of 1 1 M in SKBR3 breast cancer cells and 0 95 0 12 0 24 0 85 and 1 3 M in HT29 U937 JA16 HL60 and K562 tumor cell lines respectively Notably it exhibited greater potency than SAHA in inhibiting proliferation of U937 leukemia cells These properties make 4-iodo-SAHA valuable for investigating HDAC-related cellular processes and cancer models

Apexbio Technology LLC 4-iodo-SAHA 1219807-87-0 500mg

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4-iodo-SAHA (CAS 1219807-87-0) is a hydrophobic analog of suberoylanilide hydroxamic acid (SAHA) that functions as a histone deacetylase (HDAC) inhibitor targeting both class I and II HDACs By blocking HDAC activity 4-iodo-SAHA modulates the reversible acetylation of lysine residues on histone and non-histone proteins affecting transcriptional regulation In cellular assays 4-iodo-SAHA demonstrated antiproliferative effects with EC50 values of 1 1 M in SKBR3 breast cancer cells and 0 95 0 12 0 24 0 85 and 1 3 M in HT29 U937 JA16 HL60 and K562 tumor cell lines respectively Notably it exhibited greater potency than SAHA in inhibiting proliferation of U937 leukemia cells These properties make 4-iodo-SAHA valuable for investigating HDAC-related cellular processes and cancer models

Apexbio Technology LLC 4-iodo-SAHA 1219807-87-0 50mg

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4-iodo-SAHA (CAS 1219807-87-0) is a hydrophobic analog of suberoylanilide hydroxamic acid (SAHA) that functions as a histone deacetylase (HDAC) inhibitor targeting both class I and II HDACs By blocking HDAC activity 4-iodo-SAHA modulates the reversible acetylation of lysine residues on histone and non-histone proteins affecting transcriptional regulation In cellular assays 4-iodo-SAHA demonstrated antiproliferative effects with EC50 values of 1 1 M in SKBR3 breast cancer cells and 0 95 0 12 0 24 0 85 and 1 3 M in HT29 U937 JA16 HL60 and K562 tumor cell lines respectively Notably it exhibited greater potency than SAHA in inhibiting proliferation of U937 leukemia cells These properties make 4-iodo-SAHA valuable for investigating HDAC-related cellular processes and cancer models

Apexbio Technology LLC 4-iodo-SAHA 1219807-87-0 100mg

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4-iodo-SAHA (CAS 1219807-87-0) is a hydrophobic analog of suberoylanilide hydroxamic acid (SAHA) that functions as a histone deacetylase (HDAC) inhibitor targeting both class I and II HDACs By blocking HDAC activity 4-iodo-SAHA modulates the reversible acetylation of lysine residues on histone and non-histone proteins affecting transcriptional regulation In cellular assays 4-iodo-SAHA demonstrated antiproliferative effects with EC50 values of 1 1 M in SKBR3 breast cancer cells and 0 95 0 12 0 24 0 85 and 1 3 M in HT29 U937 JA16 HL60 and K562 tumor cell lines respectively Notably it exhibited greater potency than SAHA in inhibiting proliferation of U937 leukemia cells These properties make 4-iodo-SAHA valuable for investigating HDAC-related cellular processes and cancer models