Benzenoids
Medchemexpress LLC CC-115 hydrochloride | 1300118-55-1 | 98.01% | 372.81 | 1 ML
CC-115 hydrochloride is a potent, dual DNA-PK and mTOR kinase inhibitor. It targets both mTORC1 and mTORC2 signaling, making it a valuable tool for research applications. This compound has demonstrated significant inhibitory effects against PC-3 cell proliferation and exhibits good in vivo pharmacokinetic profiles, including high oral bioavailability in various animal models.
- Potent DNA-PK inhibitor (IC50 of 13 nM)
- Potent mTOR kinase inhibitor (IC50 of 21 nM)
- Blocks both mTORC1 and mTORC2 signaling
- Inhibits PC-3 cell proliferation with an IC50 of 138 nM
- Exhibits good in vivo pharmacokinetic profiles
- Demonstrates high oral bioavailability in mouse, rat, and dog
- Sustains inhibition through 24 hours
- Shows tumor volume reductions in vivo studies
![eMolecules Synthonix 35-Dimethylphenylzinc iodide 0.50 M in THF 25ml 627353618 D73189 312692-98-1 [null] 297.440 C8H9IZn](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695348.jpg-250.jpg)
eMolecules Synthonix 35-Dimethylphenylzinc iodide 0.50 M in THF 25ml 627353618 D73189 312692-98-1 [null] 297.440 C8H9IZn
Synthonix 35-Dimethylphenylzinc iodide 0.50 M in THF 25ml 627353618 D73189 312692-98-1 [null] 297.440 C8H9IZn
Chemscene 4-Chloro-2-iodobenzoic acid | 25g | CS-W008018 | 98% | 13421-13-1 | MFCD00060676 | 282 46 | C7H4ClIO2
Chemscene | 4-Chloro-2-iodobenzoic acid | 25g | CS-W008018 | 98% | 13421-13-1 | MFCD00060676 | 282 46 | C7H4ClIO2
Chemscene tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate | 5g | CS-W007964 | 98% | 121505-93-9 | MFCD00674101 | 218 25 | C9H18N2O4
Chemscene | tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate | 5g | CS-W007964 | 98% | 121505-93-9 | MFCD00674101 | 218 25 | C9H18N2O4
Chemscene 2-Bromo-5-iodobenzonitrile | 1g | CS-W008126 | 98% | 1252046-13-1 | MFCD09025663 | 307 92 | C7H3BrIN
Chemscene | 2-Bromo-5-iodobenzonitrile | 1g | CS-W008126 | 98% | 1252046-13-1 | MFCD09025663 | 307 92 | C7H3BrIN
eMolecules (E)-4-(2,6,6-Trimethylcyclohex-2-en-1-yl)but-3-en-2-one | 127-41-3 | MFCD00001565 | 25g
Ambeed | (E)-4-(2,6,6-Trimethylcyclohex-2-en-1-yl)but-3-en-2-one | 25g | 600826359 | A1003466 | | 127-41-3 | MFCD00001565 | 192.302 | C13H20O
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eMolecules Building Block Tool
Apexbio Technology LLC Cyclophosphamide monohydrate 6055-19-2 10g
Cyclophosphamide monohydrate is an alkylating cytotoxic agent exhibiting antitumor activity primarily via metabolic activation As a prodrug it undergoes hepatic biotransformation mediated by cytochrome P450 enzymes forming active alkylating metabolites such as 4-hydroxycyclophosphamide which exert cytotoxic effects through interactions with cellular DNA Cyclophosphamide also reversibly inhibits acetylcholinesterase (AChE) displaying an IC50 of approximately 511 M It is widely utilized in experimental cancer studies particularly in pediatric oncology where alterations in drug metabolism or drug-drug interactions impacting cyclophosphamide clearance and therapeutic outcomes have been explored
Echelon Biosciences Research Labs 306OI10 100MG
306Oi10, 95% 100mg CAS#2322290-93-5 C59H115N3O8 MW:994.58
STA PHARMACEUTICAL US LLC (S)-alpha-(Fmoc-amino)-4-hydroxycyclohexaneacetic acid | 100 g | CAS 1416444-92-2 | MDL MFCD22631473
(S)-alpha-(Fmoc-amino)-4-hydroxycyclohexaneacetic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1416444-92-2
- MDL: MFCD22631473
- InChIKey: LDKHGFYFIBBLAC-XFMWISLNSA-N
- Molecular Weight: 395.455
- Molecular Formula: C23H25NO5
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-hydroxycyclohexyl)acetic acid
- SMILES: OC1CCC([C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)C(O)=O)CC1
Chemscene 4-Bromo-2 6-difluorobenzonitrile | 100g | CS-W008282 | 98% | 123843-67-4 | MFCD01310981 | 218 | C7H2BrF2N
Chemscene | 4-Bromo-2 6-difluorobenzonitrile | 100g | CS-W008282 | 98% | 123843-67-4 | MFCD01310981 | 218 | C7H2BrF2N