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Organic compounds that are derived from or have a benzene group in their molecular structure. Benzene is an aromatic organic molecule composed of 6 carbon atoms and 6 hydrogen atoms that form a ring. Includes derivatives and substituted molecules.
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BETd-246 is a second-generation PROTAC-based BET bromodomain degrader that links cereblon and BET ligands to induce selective BET protein degradation. It is provided as a research-grade solid (light yellow) with reported purity of 98.34% and a molecular weight of 946.02, and is highly soluble in DMSO for in vitro and formulation use.
PROTAC mechanism for targeted BET protein degradation.
Reported selectivity and antitumor potency in preclinical studies.
High purity suitable for research applications.
High solubility in DMSO enabling concentrated stock solutions.
Recommended storage as solid at -20°C under inert atmosphere for stability.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Ac-Endothelin-1 16-21 human is a selective agonist targeting the ETB subtype of G protein-coupled endothelin receptors It is designed to activate ETB receptors thereby modulating phospholipase C-mediated signaling pathways and vascular function Ac-Endothelin-1 16-21 human exerts its biological activity primarily through selective ETB receptor activation leading to vasoconstrictive effects Based on these pharmacological properties Ac-Endothelin-1 16-21 human holds research potential in studies analyzing vascular function as well as investigations of cardiovascular and renal pathophysiology
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More