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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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A long-chain saturated fatty acid; a major component of cocoa butter and has also been found in beef fat and vegetable oils; does not induce hypercholesterolemia or raise LDL-cholesterol unlike many long-chain saturated fatty acids
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A bioactive fatty acid; accumulates in PMA-stimulated primary human monocytes and neutrophils as well as murine neutrophils; induces DNA release from primary human neutrophils
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SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. It exhibits anti-COVID-19 activity by targeting Mpro (IC50 of 30 nM).
Orally active inhibitor of IL-1β converting enzyme and caspase-1
Exhibits anti-COVID-19 activity
Potently reduces carrageenin-induced paw oedema
Displays analgesic activity in the Randall-Selitto yeast-inflamed paw pressure test
For research use only
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Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. AU-224 is an orally available benzamide derivative that is a potent gastrointestinal prokinetic. Purity 98.08%
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MD-224 is a highly potent and effective degrader of the Human murine double minute 2 (MDM2) protein the main cellular inhibitor of the tumor suppressor p53 It strongly inhibits cell growth in leukemia cell lines with wild-type p53 and induces complete and lasting tumor regression in the RS4 11 xenograft tumor model
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