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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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Dimethyl pentadecanedioate is the dimethyl ester of pentadecanedioic acid used as a research reagent and synthetic intermediate. It is supplied as a solid with CAS number 36575-82-3 and a GC-reported purity of 98.95% (COA). Typical applications include use as a building block in organic synthesis and materials research.
High purity suitable for research applications (GC purity 98.9%).
Dimethyl ester functionality useful as a synthetic intermediate.
Solid form with a melting point near 43-44 °C for easy handling.
Soluble in common organic solvents such as ethanol and chloroform.
Available in laboratory pack sizes including 25 G.
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Dynole 2-24 is an indole-based dynamin GTPase inhibitor with an IC₅₀ of 0.56 μM for dynamin I. This compound is non-toxic and demonstrates increased potency against dynamin I and II both in vitro and within cells, with an IC₅₀ (CME) of 1.9 μM. It exhibits a 4.4-fold selectivity for dynamin I. Dynole 2-24 acts as an active in-cell inhibitor of clathrin-mediated endocytosis (CME).
Indole-based dynamin GTPase inhibitor.
IC₅₀ of 0.56 μM for dynamin I.
Nontoxic.
Increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM).
Shows 4.4-fold selectivity for dynamin I.
Active in-cell inhibitor of clathrin-mediated endocytosis.
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Pentadecane is a floral volatile antimalarial agent with anti-inflammatory, analgesic, and antipyretic activities. It is a colorless to off-white liquid that can inhibit the growth of parasites such as Leishmania and avoid infection of macrophages. Store this product at room temperature for up to 3 years.
Inhibits growth of parasites such as Leishmania
Avoids infection of macrophages
Possesses anti-inflammatory, analgesic, and antipyretic activities
Ships at room temperature
Store at room temperature for 3 years
Store in solvent at -80°C for 2 years, or -20°C for 1 year
Keep container tightly sealed in a cool, well-ventilated area
Keep away from direct sunlight and sources of ignition
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Dynole 2-24 is an indole-based dynamin GTPase inhibitor. It is nontoxic and demonstrates increased potency against dynamin I and II both in vitro and within cells. This compound also exhibits selective inhibition of dynamin I and is an active in-cell inhibitor of clathrin-mediated endocytosis.
Indole-based dynamin GTPase inhibitor.
Has an IC50 of 0.56 μM for dynamin I.
Nontoxic.
Shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM).
Displays 4.4-fold selectivity for dynamin I.
Functions as an active in-cell inhibitor of clathrin-mediated endocytosis.
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MD-224 is a proteolysis-targeting chimera (PROTAC) that potently degrades murine double minute 2 (MDM2). It is used as a research compound to probe the MDM2-p53 pathway and evaluate MDM2-targeted degradation in oncology and cell biology studies.
Potent MDM2 degrader active at sub-nanomolar concentrations
Suitable for cellular and biochemical studies of p53 signaling
Provided as a high-purity solid for research use
Available in laboratory-scale pack sizes, including 25 mg
Molecular formula C48H43Cl2FN6O6; molecular weight 889.80
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Dodecane (Ba 51-090453) is an ester product Dodecane is an aliphatic hydrocarbon Dodecane can result in a high TNF- expression and transepidermal waterloss (TEWL)[1]
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I-287 is an orally active, selective PAR2 inhibitor that acts as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant (CFA)-induced inflammation in mice and can be utilized for inflammation/immunology research.
Inhibits PAR2-mediated activation of Gαq and Gα12/13.
No effect on PAR2-mediated recruitment of βarrestin2 or receptor internalization.
Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells.
Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells.
Reduces CFA-induced inflammation in C57BL/6J mice.
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TPI-287 is a brain-penetrant taxane-class microtubule stabilizer intended for preclinical oncology research. It stabilizes microtubules, shows antineoplastic activity in models of metastatic breast cancer to the brain, and is supplied as a research-grade small molecule for laboratory investigation.
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N-Heptadecane (heptadecane) is a straight-chain saturated hydrocarbon (C17H36) used as a reagent and analytical standard in research and analytical laboratories. It is supplied for laboratory use only and is available in multiple pack sizes, including a 1 kg package.
Straight-chain alkane suitable as an analytical standard.
High purity, 97.2%, for consistent analytical results.
Nonpolar and hydrophobic, useful in chromatography and method development.
Available in multiple pack sizes to support both small-scale and bulk use.
Provided with SDS and COA documentation for handling and quality verification.
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